Monomer-on-Monomer (MoM) Mitsunobu Reaction: Facile Purification Utilizing Surface-Initiated Sequestration von Maity, Pradip K, Rolfe, Alan, Samarakoon, Thiwanka B, Faisal, Saqib, Kurtz, Ryan D, Long, Toby R, Schätz, Alexander, Flynn, Daniel L, Grass, Robert N, Stark, Wendelin J, Reiser, Oliver, Hanson, Paul R

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High-Load, Oligomeric Dichlorotriazine: A Versatile ROMP-Derived Reagent and Scavenger von Rolfe, Alan, Probst, Donald A, Volp, Kelly A, Omar, Iman, Flynn, Daniel L, Hanson, Paul R

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Exploring chemical diversity via a modular reaction pairing strategy von Loh, Joanna K, Yoon, Sun Young, Samarakoon, Thiwanka B, Rolfe, Alan, Porubsky, Patrick, Neuenswander, Benjamin, Lushington, Gerald H, Hanson, Paul R

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Abstract 2467: Heme-CMap: Generation and characterization of ~20K L1000 profiles across 11 hematologic malignant lines von Huang, Chia-Ling, Yang, Andrew, Natoli, Ted, Litichevskiy, Lev, Vaillancourt, Frederic, Rolfe, Alan, Xiao, Yonghong, Subramanian, Aravind, Yu, Lihua

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The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity von Nguyen, Tuong-Vi, Yao, Shihua, Wang, Yahong, Rolfe, Alan, Selvaraj, Anand, Darman, Rachel, Ke, Jiyuan, Warmuth, Markus, Smith, Peter G., Larsen, Nicholas A., Yu, Lihua, Zhu, Ping, Fekkes, Peter, Vaillancourt, Frédéric H., Bolduc, David M.

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Formal [4+3] Epoxide Cascade Reaction via a Complementary Ambiphilic Pairing Strategy von Rolfe, Alan, Samarakoon, Thiwanka B, Hanson, Paul R

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Domino Heck–Aza‐Michael Reactions: A One‐Pot, Sequential Three‐Component Approach to 1,1‐Dioxido‐1,2‐benzisothiazoline‐3‐acetic Acid von Rolfe, Alan, Young, Kyle, Hanson, Paul R.

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Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket von Yao, Shihua, Nguyen, Tuong-Vi, Rolfe, Alan, Agrawal, Anant A., Ke, Jiyuan, Peng, Shouyong, Colombo, Federico, Yu, Sean, Bouchard, Patricia, Wu, Jiayi, Huang, Kuan-Chun, Bao, Xingfeng, Omoto, Kiyoyuki, Selvaraj, Anand, Yu, Lihua, Ioannidis, Stephanos, Vaillancourt, Frédéric H., Zhu, Ping, Larsen, Nicholas A., Bolduc, David M.

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α-Haloarylsulfonamides: multiple cyclization pathways to skeletally diverse benzofused sultams von Rayabarapu, Dinesh Kumar, Zhou, Aihua, Jeon, Kyu Ok, Samarakoon, Thiwanka, Rolfe, Alan, Siddiqui, Hina, Hanson, Paul R.

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Abstract 2334: Discovery of selective inhibitors of carbamoyl phosphate synthetase I (CPS1) to modulate cancer relevant metabolic pathways von Yao, Shihua, Nguyen, Tuong-Vi, Rolfe, Alan, Agrawal, Anant A., Ke, Jiyuan, Peng, Shouyong, Colombo, Federico, Yu, Sean, Bouchard, Patricia, Wu, Jiayi, Huang, Kuan-Chun, Bao, Xingfeng, Omoto, Kiyoyuki, Selvaraj, Anand, Yu, Lihua, Ioannidis, Stephanos, Vaillancourt, Frédéric H., Zhu, Ping, Larsen, Nicholas A., Bolduc, David M.

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Multi-purpose deployer for ITER in-vessel maintenance von Choi, Chang-Hwan, Tesini, Alessandro, Subramanian, Rajendran, Rolfe, Alan, Mills, Simon, Scott, Robin, Froud, Tim, Haist, Bernhard, McCarron, Eddie

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Microwave-assisted sequential one-pot protocol to benzothiadiazin-3-one-1,1-dioxides via a copper-catalyzed N-arylation strategy von Rolfe, Alan, Hanson, Paul R.

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Scaling Out by Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS): Multi-Gram Synthesis of Bromo- and Fluoro-benzofused Sultams Benzthiaoxazepine-1,1-dioxides von Ullah, Farman, Samarakoon, Thiwanka, Rolfe, Alan, Kurtz, Ryan D., Hanson, Paul R., Organ, Michael G.

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Silica-Supported Oligomeric Benzyl Phosphate (Si-OBP) and Triazole Phosphate (Si-OTP) Alkylating Reagents von Maity, Pradip K, Faisal, Saqib, Rolfe, Alan, Stoianova, Diana, Hanson, Paul R

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Synthesis of High-Load, Hybrid Silica-Immobilized Heterocyclic Benzyl Phosphate (Si–OHBP) and Triazolyl Phosphate (Si–OHTP) Alkylating Reagents von Faisal, Saqib, Maity, Pradip K., Zang, Qin, Rolfe, Alan, Hanson, Paul R.

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Discovery of 2,6-Dimethylpiperazines as Allosteric Inhibitors of CPS1 von Rolfe, Alan, Yao, Shihua, Toung-Vi Nguyen, Omoto, Kiyoyuki, Colombo, Federico, Virrankoski, Milena, Vaillancourt, Frederic H., Yu, Lihua, Cook, Andrew, Reynolds, Dominic, Ioannidis, Stephanos, Zhu, Ping, Larsen, Nicholas A., Bolduc, David M.

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Reagent based DOS: a "Click, Click, Cyclize" strategy to probe chemical space von Rolfe, Alan, Lushington, Gerald H, Hanson, Paul R

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High-Load, Hybrid Si-ROMP Reagents von Rolfe, Alan, Loh, Joanna K, Maity, Pradip K, Hanson, Paul R

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Metathesis cascade strategies (ROM–RCM–CM): a DOS approach to skeletally diverse sultams von Jeon, Kyu Ok, Rayabarapu, Dinesh, Rolfe, Alan, Volp, Kelly, Omar, Iman, Hanson, Paul R.

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A Modular Reaction Pairing Approach to the Diversity-Oriented Synthesis of Fused- and Bridged-Polycyclic Sultams von Samarakoon, Thiwanka B, Loh, Joanna K, Rolfe, Alan, Le, Lisa S, Yoon, Sun Young, Lushington, Gerald H, Hanson, Paul. R

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