Combining ibrutinib and checkpoint blockade improves CD8+ T-cell function and control of chronic lymphocytic leukemia in Em-TCL1 mice von Hanna, Bola S, Yazdanparast, Haniyeh, Demerdash, Yasmin, Roessner, Philipp M, Schulz, Ralph, Lichter, Peter, Stilgenbauer, Stephan, Seiffert, Martina

Volltext

Phosphoinositide 3-Kinase Signaling in the Tumor Microenvironment: What Do We Need to Consider When Treating Chronic Lymphocytic Leukemia With PI3K Inhibitors? von Aydin, Ebru, Faehling, Sebastian, Saleh, Mariam, Llao Cid, Laura, Seiffert, Martina, Roessner, Philipp M.

Volltext

Interleukin-27 potentiates CD8+ T-cell-mediated antitumor immunity in chronic lymphocytic leukemia von Pagano, Giulia, Botana, Iria Fernandez, Wierz, Marina, Roessner, Philipp M., Ioannou, Nikolaos, Zhou, Xiangda, Al-Hity, Gheed, Borne, Coralie, Gargiulo, Ernesto, Gonder, Susanne, Qu, Bin, Stamatopoulos, Basile, Ramsay, Alan G., Seiffert, Martina, Largeot, Anne, Moussay, Etienne, Paggetti, Jerome

Volltext

T-cells in chronic lymphocytic leukemia: Guardians or drivers of disease? von Roessner, Philipp M., Seiffert, Martina

Volltext

Sequential therapy for the locally advanced larynx and hypopharynx cancer subgroup in TAX 324: survival, surgery, and organ preservation von Posner, M.R., Norris, C.M., Wirth, L.J., Shin, D.M., Cullen, K.J., Winquist, E.W., Blajman, C.R., Mickiewicz, E.A., Frenette, G.P., Plinar, L.F., Cohen, R.B., Steinbrenner, L.M., Freue, J.M., Gorbunova, V.A., Tjulandin, S.A., Raez, L.E., Adkins, D.R., Tishler, R.B., Roessner, M.R., Haddad, R.I.

Volltext

Rejection of adoptively transferred Eµ-TCL1 chronic lymphocytic leukemia cells in C57BL/6 substrains or knockout mouse lines von Öztürk, Selcen, Roessner, Philipp M., Schulze-Edinghausen, Lena, Yazdanparast, Haniyeh, Kalter, Verena, Lichter, Peter, Hanna, Bola S., Seiffert, Martina

Volltext

Simultaneous Inhibition of PI3Kgamma and PI3Kdelta Deteriorates T‐cell Function With Implications for Chronic Lymphocytic Leukemia von Faehling, Sebastian, Coelho, Mariana, Floerchinger, Alessia, Schneider, Christof, Stilgenbauer, Stephan, Lichter, Peter, Seiffert, Martina, Roessner, Philipp M.

Volltext

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL von Wierzbinska, Justyna A., Toth, Reka, Ishaque, Naveed, Rippe, Karsten, Mallm, Jan-Philipp, Klett, Lara C., Mertens, Daniel, Zenz, Thorsten, Hielscher, Thomas, Seifert, Marc, Kuppers, Ralf, Assenov, Yassen, Lutsik, Pavlo, Stilgenbauer, Stephan, Roessner, Philipp M., Seiffert, Martina, Byrd, John, Oakes, Christopher C., Plass, Christoph, Lipka, Daniel B.

Volltext

Publisher Correction: T cells in chronic lymphocytic leukemia: guardians or drivers of disease? von Roessner, Philipp M., Seiffert, Martina

Volltext

Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity von Hanna, Bola S., Llaó-Cid, Laura, Iskar, Murat, Roessner, Philipp M., Klett, Lara C., Wong, John K.L., Paul, Yashna, Ioannou, Nikolaos, Öztürk, Selcen, Mack, Norman, Kalter, Verena, Colomer, Dolors, Campo, Elías, Bloehdorn, Johannes, Stilgenbauer, Stephan, Dietrich, Sascha, Schmidt, Manfred, Gabriel, Richard, Rippe, Karsten, Feuerer, Markus, Ramsay, Alan G., Lichter, Peter, Zapatka, Marc, Seiffert, Martina

Volltext

Control of chronic lymphocytic leukemia development by clonally-expanded CD8+ T-cells that undergo functional exhaustion in secondary lymphoid tissues von Hanna, Bola S., Roessner, Philipp M., Yazdanparast, Haniyeh, Colomer, Dolors, Campo, Elias, Kugler, Sabrina, Yosifov, Deyan, Stilgenbauer, Stephan, Schmidt, Manfred, Gabriel, Richard, Lichter, Peter, Seiffert, Martina

Volltext

PI3Kδ inhibition modulates regulatory and effector T-cell differentiation and function in chronic lymphocytic leukemia von Hanna, Bola S., Roessner, Philipp M., Scheffold, Annika, Jebaraj, Billy M. C., Demerdash, Yasmin, Öztürk, Selcen, Lichter, Peter, Stilgenbauer, Stephan, Seiffert, Martina

Volltext

EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia von Llaó-Cid, Laura, Roessner, Philipp M., Chapaprieta, Vicente, Öztürk, Selcen, Roider, Tobias, Bordas, Marie, Izcue, Ana, Colomer, Dolors, Dietrich, Sascha, Stilgenbauer, Stephan, Hanna, Bola, Martín-Subero, José Ignacio, Seiffert, Martina

Volltext

IDO1-Targeted Therapy Does Not Control Disease Development in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia von Öztürk, Selcen, Kalter, Verena, Roessner, Philipp M, Sunbul, Murat, Seiffert, Martina

Volltext

Evaluation of vecabrutinib as a model for noncovalent BTK/ITK inhibition for treatment of chronic lymphocytic leukemia von Jebaraj, Billy Michael Chelliah, Müller, Annika, Dheenadayalan, Rashmi Priyadharshini, Endres, Sascha, Roessner, Philipp M., Seyfried, Felix, Walliser, Claudia, Wist, Martin, Qi, Jialei, Tausch, Eugen, Mertens, Daniel, Fox, Judith A., Debatin, Klaus-Michael, Meyer, Lüder Hinrich, Taverna, Pietro, Seiffert, Martina, Gierschik, Peter, Stilgenbauer, Stephan

Volltext

EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia von Roessner, Philipp M., Llaó Cid, Laura, Lupar, Ekaterina, Roider, Tobias, Bordas, Marie, Schifflers, Christoph, Arseni, Lavinia, Gaupel, Ann-Christin, Kilpert, Fabian, Krötschel, Marit, Arnold, Sebastian J., Sellner, Leopold, Colomer, Dolors, Stilgenbauer, Stephan, Dietrich, Sascha, Lichter, Peter, Izcue, Ana, Seiffert, Martina

Volltext

Interleukin-27 potentiates CD8+ T-cell-mediated anti-tumor immunity in chronic lymphocytic leukemia von Pagano, Giulia, Botana, Iria Fernandez, Wierz, Marina, Roessner, Philipp M, Ioannou, Nikolaos, Zhou, Xiangda, Al-Hity, Gheed, Borne, Coralie, Gargiulo, Ernesto, Gonder, Susanne, Qu, Bin, Stamatopoulos, Basile, Ramsay, Alan G, Seiffert, Martina, Largeot, Anne, Moussay, Etienne, Paggetti, Jerome

Volltext

TBET‐expressing Th1 CD4+ T cells accumulate in chronic lymphocytic leukaemia without affecting disease progression in Eµ‐TCL1 mice von Roessner, Philipp M., Hanna, Bola S., Öztürk, Selcen, Schulz, Ralph, Llaó Cid, Laura, Yazdanparast, Haniyeh, Scheffold, Annika, Colomer, Dolors, Stilgenbauer, Stephan, Lichter, Peter, Seiffert, Martina

Volltext

Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients von Öztürk, Selcen, Paul, Yashna, Afzal, Saira, Gil-Farina, Irene, Jauch, Anna, Bruch, Peter-Martin, Kalter, Verena, Hanna, Bola, Arseni, Lavinia, Roessner, Philipp M., Schmidt, Manfred, Stilgenbauer, Stephan, Dietrich, Sascha, Lichter, Peter, Zapatka, Marc, Seiffert, Martina

Volltext

P598: EBI3/IL‐27 DEPLETED MICROENVIRONMENT FAVOURS TUMOUR PROGRESSION IN CHRONIC LYMPHOCYTIC LEUKAEMIA von Botana, I. C., Pagano, G., Marina, W., Roessner, P. M., Qu, B., Ramsay, A., Stamatopoulos, B., Seiffert, M., Paggetti, J., Moussay, E.

Volltext