Combating castration-resistant prostate cancer by co-targeting the epigenetic regulators EZH2 and HDAC von Schade, Amy E, Kuzmickas, Ryan, Rodriguez, Carrie L, Mattioli, Kaia, Enos, Miriam, Gardner, Alycia, Cichowski, Karen

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AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution von Schade, Amy E., Perurena, Naiara, Yang, Yoona, Rodriguez, Carrie L., Krishnan, Anjana, Gardner, Alycia, Loi, Patrick, Xu, Yilin, Nguyen, Van T. M., Mastellone, G. M., Pilla, Natalie F., Watanabe, Marina, Ota, Keiichi, Davis, Rachel A., Mattioli, Kaia, Xiang, Dongxi, Zoeller, Jason J., Lin, Jia-Ren, Morganti, Stefania, Garrido-Castro, Ana C., Tolaney, Sara M., Li, Zhe, Barbie, David A., Sorger, Peter K., Helin, Kristian, Santagata, Sandro, Knott, Simon R. V., Cichowski, Karen

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Combating castration-resistant prostate cancer by co-targeting the epigenetic regulators EZH2 and HDAC von Amy E. Schade, Ryan Kuzmickas, Carrie L. Rodriguez, Kaia Mattioli, Miriam Enos, Alycia Gardner, Karen Cichowski

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Abstract P1-13-06: Loss of emerging tumor and metastasis suppressor RasGAPs mediates therapeutic resistance in HER2+ breast cancer von Perurena, Naiara, Pilla, Natalie, Schade, Amy, Watanabe, Marina, Loi, Patrick, Rodriguez, Carrie L., Gardner, Alycia M., Cichowski, Karen

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Abstract P4-08-11: AKT and EZH2 inhibitors kill TNBCs by hijacking mechanisms of involution von Schade, Amy, Perurena, Naiara, Watanabe, Marina, Rodriguez, Carrie L., Loi, Patrick, Pilla, Natalie, Davis, Rachel A., Mattioli, Kaia, Xiang, Dongxi, Zoeller, Jason J., Li, Zhe, Garrido-Castro, Ana C., Tolaney, Sara, Cichowski, Karen

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miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis von Rosenberger, Carrie M, Podyminogin, Rebecca L, Diercks, Alan H, Treuting, Piper M, Peschon, Jacques J, Rodriguez, David, Gundapuneni, Madhumati, Weiss, Mitchell J, Aderem, Alan

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Risk of cirrhosis-related complications in patients with advanced fibrosis following hepatitis C virus eradication von van der Meer, Adriaan J, Feld, Jordan J, Hofer, Harald, Almasio, Piero L, Calvaruso, Vincenza, Fernández-Rodríguez, Conrado M, Aleman, Soo, Ganne-Carrié, Nathalie, D’Ambrosio, Roberta, Pol, Stanislas, Trapero-Marugan, Maria, Maan, Raoel, Moreno-Otero, Ricardo, Mallet, Vincent, Hultcrantz, Rolf, Weiland, Ola, Rutter, Karoline, Di Marco, Vito, Alonso, Sonia, Bruno, Savino, Colombo, Massimo, de Knegt, Robert J, Veldt, Bart J, Hansen, Bettina E, Janssen, Harry L.A

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Recurrent and functional regulatory mutations in breast cancer von Rheinbay, Esther, Parasuraman, Prasanna, Grimsby, Jonna, Tiao, Grace, Engreitz, Jesse M., Kim, Jaegil, Lawrence, Michael S., Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Cortes, Maria L., Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Gabriel, Stacey B., Meyerson, Matthew, Golub, Todd R., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Lander, Eric S., Getz, Gad

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Discovery, Structure–Activity Relationship, and Biological Characterization of a Novel Series of 6‑((1H‑Pyrazolo[4,3‑b]pyridin-3-yl)amino)-benzo[d]isothiazole-3-carboxamides as Pos... von Bollinger, Sean R, Engers, Darren W, Panarese, Joseph D, West, Mary, Engers, Julie L, Loch, Matthew T, Rodriguez, Alice L, Blobaum, Anna L, Jones, Carrie K, Thompson Gray, Analisa, Conn, P. Jeffrey, Lindsley, Craig W, Niswender, Colleen M, Hopkins, Corey R

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ANCA-associated vasculitis with cardiac valve vegetations in two teenage males: two case reports and a literature review von Theisen, Alexandra, Phillips, Carrie L, Rodriguez, Martha

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Replicative DNA polymerase δ but not ε proofreads errors in Cis and in Trans von Flood, Carrie L, Rodriguez, Gina P, Bao, Gaobin, Shockley, Arthur H, Kow, Yoke Wah, Crouse, Gray F

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Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M 5 Muscarinic Acetylcholine Receptor von Li, Jinming, Orsi, Douglas L, Engers, Julie L, Long, Madeline F, Capstick, Rory A, Maurer, Mallory A, Presley, Christopher C, Vinson, Paige N, Rodriguez, Alice L, Han, Allie, Cho, Hyekyung P, Chang, Sichen, Jackson, Megan, Bubser, Michael, Blobaum, Anna L, Boutaud, Olivier, Nader, Michael A, Niswender, Colleen M, Conn, P Jeffrey, Jones, Carrie K, Lindsley, Craig W, Han, Changho

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Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor von Li, Jinming, Orsi, Douglas L., Engers, Julie L., Long, Madeline F., Capstick, Rory A., Maurer, Mallory A., Presley, Christopher C., Vinson, Paige N., Rodriguez, Alice L., Han, Allie, Cho, Hyekyung P., Chang, Sichen, Jackson, Megan, Bubser, Michael, Blobaum, Anna L., Boutaud, Olivier, Nader, Michael A., Niswender, Colleen M., Conn, P. Jeffrey, Jones, Carrie K., Lindsley, Craig W., Han, Changho

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Recommendations for Defining and Reporting Adherence Measured by Biometric Monitoring Technologies: Systematic Review von Olaye, Iredia M, Belovsky, Mia P, Bataille, Lauren, Cheng, Royce, Ciger, Ali, Fortuna, Karen L, Izmailova, Elena S, McCall, Debbe, Miller, Christopher J, Muehlhausen, Willie, Northcott, Carrie A, Rodriguez-Chavez, Isaac R, Pratap, Abhishek, Vandendriessche, Benjamin, Zisman-Ilani, Yaara, Bakker, Jessie P

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Discovery, Characterization, and Antiparkinsonian Effect of Novel Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 von Niswender, Colleen M, Johnson, Kari A, Weaver, C David, Jones, Carrie K, Xiang, Zixiu, Luo, Qingwei, Rodriguez, Alice L, Marlo, Joy E, de Paulis, Tomas, Thompson, Analisa D, Days, Emily L, Nalywajko, Tasha, Austin, Cheryl A, Williams, Michael Baxter, Ayala, Jennifer E, Williams, Richard, Lindsley, Craig W, Conn, P Jeffrey

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Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells von Bendris, Nawal, Stearns, Carrie J S, Reis, Carlos R, Rodriguez-Canales, Jaime, Liu, Hui, Witkiewicz, Agnieszka W, Schmid, Sandra L

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The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes von Ahmed, Mohamed, Casanova, Nancy G, Zaghloul, Nahla, Gupta, Akash, Rodriguez, Marisela, Robbins, Ian R, Kempf, Carrie L, Sun, Xiaoguang, Song, Jin H, Hernon, Vivian Reyes, Sammani, Saad, Camp, Sara M, Moreira, Alvaro, Hsu, Chaur-Dong, Garcia, Joe G N

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Design and Synthesis of N‑Aryl Phenoxyethoxy Pyridinones as Highly Selective and CNS Penetrant mGlu3 NAMs von Engers, Julie L, Bollinger, Katrina A, Weiner, Rebecca L, Rodriguez, Alice L, Long, Madeline F, Breiner, Megan M, Chang, Sichen, Bollinger, Sean R, Bubser, Michael, Jones, Carrie K, Morrison, Ryan D, Bridges, Thomas M, Blobaum, Anna L, Niswender, Colleen M, Conn, P. Jeffrey, Emmitte, Kyle A, Lindsley, Craig W

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Insulin Bidirectionally Alters NAc Glutamatergic Transmission: Interactions between Insulin Receptor Activation, Endogenous Opioids, and Glutamate Release von Fetterly, Tracy L., Oginsky, Max F., Nieto, Allison M., Alonso-Caraballo, Yanaira, Santana-Rodriguez, Zuleirys, Ferrario, Carrie R.

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Challenges in the development of an M 4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides von Tarr, James C, Wood, Michael R, Noetzel, Meredith J, Bertron, Jeanette L, Weiner, Rebecca L, Rodriguez, Alice L, Lamsal, Atin, Byers, Frank W, Chang, Sichen, Cho, Hyekyung P, Jones, Carrie K, Niswender, Colleen M, Wood, Michael W, Brandon, Nicholas J, Duggan, Mark E, Conn, P Jeffrey, Bridges, Thomas M, Lindsley, Craig W

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