Atomic Structure of PDE4: Insights into Phosphodiesterase Mechanism and Specificity von Xu, Robert X., Hassell, Anne M., Vanderwall, Dana, Lambert, Millard H., Holmes, William D., Luther, Michael A., Rocque, Warren J., Milburn, Michael V., Zhao, Yingdong, Ke, Hengming, Nolte, Robert T.

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Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis von Bramson, H. Neal, Corona, John, Davis, Stephen T, Dickerson, Scott H, Edelstein, Mark, Frye, Stephen V, Gampe, Robert T, Harris, Phil A, Hassell, Anne, Holmes, William D, Hunter, Robert N, Lackey, Karen E, Lovejoy, Brett, Luzzio, Michael J, Montana, Val, Rocque, Warren J, Rusnak, David, Shewchuk, Lisa, Veal, James M, Walker, Duncan H, Kuyper, Lee F

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Crystal Structures of the Catalytic Domain of Phosphodiesterase 4B Complexed with AMP, 8-Br-AMP, and Rolipram von Xu, Robert X, Rocque, Warren J, Lambert, Millard H, Vanderwall, Dana E, Luther, Michael A, Nolte, Robert T

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Binding Mode of the 4-Anilinoquinazoline Class of Protein Kinase Inhibitor:  X-ray Crystallographic Studies of 4-Anilinoquinazolines Bound to Cyclin-Dependent Kinase 2 and p38 Kina... von Shewchuk, Lisa, Hassell, Anne, Wisely, Bruce, Rocque, Warren, Holmes, William, Veal, James, Kuyper, Lee F

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Crystallization of protein-ligand complexes von Hassell, Anne M., An, Gang, Bledsoe, Randy K., Bynum, Jane M., Carter III, H. Luke, Deng, Su-Jun J., Gampe, Robert T., Grisard, Tamara E., Madauss, Kevin P., Nolte, Robert T., Rocque, Warren J., Wang, Liping, Weaver, Kurt L., Williams, Shawn P., Wisely, G. Bruce, Xu, Robert, Shewchuk, Lisa M.

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Crystal Structure of the Catalytic Domain of the Human Cell Cycle Control Phosphatase, Cdc25A von Fauman, Eric B., Cogswell, John P., Lovejoy, Brett, Rocque, Warren J., Holmes, William, Montana, Valerie G., Piwnica-Worms, Helen, Rink, Martin J., Saper, Mark A.

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Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors von Davis, Stephen T., Benson, Bill G., Bramson, H. Neal, Chapman, Dennis E., Dickerson, Scott H., Dold, Karen M., Eberwein, Derek J., Edelstein, Mark, Frye, Stephen V., Gampe, Robert T., Griffin, Robert J., Harris, Philip A., Hassell, Anne M., Holmes, William D., Hunter, Robert N., Knick, Victoria B., Lackey, Karen, Lovejoy, Brett, Luzzio, Michael J., Murray, Doris, Parker, Patricia, Rocque, Warren J., Shewchuk, Lisa, Veal, James M., Walker, Duncan H., Kuyper, Lee F.

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Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library von Rowley, Ann M., Yao, Gang, Andrews, Logan, Bedermann, Aaron, Biddulph, Ross, Bingham, Ryan, Brady, Jennifer J., Buxton, Rachel, Cecconie, Ted, Cooper, Rona, Csakai, Adam, Gao, Enoch N., Grenier-Davies, Melissa C., Lawler, Meghan, Lian, Yiqian, Macina, Justyna, Macphee, Colin, Marcaurelle, Lisa, Martin, John, McCormick, Patricia, Pindoria, Rekha, Rauch, Martin, Rocque, Warren, Shen, Yingnian, Shewchuk, Lisa M., Squire, Michael, Stebbeds, Will, Tear, Westley, Wang, Xin, Ward, Paris, Xiao, Shouhua

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Identification of Peptides That Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein von DENG, Su-Jun, PEARCE, Kenneth H, ALEXANDER, Kenneth A, UNDERWOOD, Mark R, DIXON, Eric P, HARTLEY, Kelly A, STANLEY, Thomas B, LOBE, David C, GARVEY, Edward P, KOST, Thomas A, PETTY, Regina L, ROCQUE, Warren J

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Human Recombinant Phosphodiesterase 4B2B Binds (R)-Rolipram at a Single Site with Two Affinities von Rocque, Warren J, Tian, Gaochao, Wiseman, Jeffrey S, Holmes, William D, Zajac-Thompson, Irene, Willard, Derril H, Patel, Indravaden R, Wisely, G. Bruce, Clay, William C, Kadwell, Sue H, Hoffman, Christine R, Luther, Michael A

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Effects of pH on bacterial porin function von Todt, Jill C, Rocque, Warren J, McGroarty, Estelle J

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Subunit Affinities and Stoichiometries of the Human Papillomavirus Type 11 E1:E2:DNA Complex von Chao, Shih-Fong, Rocque, Warren J, Daniel, Selwyn, Czyzyk, Linda E, Phelps, William C, Alexander, Kenneth A

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Solution Studies of Recombinant Human Stromal-Cell-Derived Factor-1 von Holmes, William D., Consler, Thomas G., Dallas, Walter S., Rocque, Warren J., Willard, Derril H.

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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α von Moss, Marcia L, Jin, S.-L. Catherine, Milla, Marcos E, Burkhart, William, Carter, H. Luke, Chen, Wen-Ji, Clay, William C, Didsbury, John R, Hassler, Daniel, Hoffman, Christine R, Kost, Thomas A, Lambert, Millard H, Leesnitzer, M. Anthony, McCauley, Philip, McGeehan, Gerard, Mitchell, Justin, Moyer, Mary, Pahel, Gregory, Rocque, Warren, Overton, Laurie K, Schoenen, Frank, Seaton, Theresa, Su, Jui-Lan, Warner, Janet, Willard, Derril, Becherer, J. David

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Phosphorylation of a cAMP-specific phosphodiesterase (HSPDE4B2B) by mitogen-activated protein kinase von Lenhard, J M, Kassel, D B, Rocque, W J, Hamacher, L, Holmes, W D, Patel, I, Hoffman, C, Luther, M

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Use of Photoactivatable Peptide Substrates of Saccharomyces cerevisiae Myristoyl-CoA:Protein N-Myristoyltransferase (Nmt1p) to Characterize a Myristoyl-CoA-Nmt1p-Peptide Ternary Co... von Rudnick, D A, Rocque, W J, McWherter, C A, Toth, M V, Jackson-Machelski, E, Gordon, J I

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Crystal Structure and Mutational Analysis of the Human CDK2 Kinase Complex with Cell Cycle–Regulatory Protein CksHs1 von Bourne, Yves, Watson, Mark H, Hickey, Michael J, Holmes, William, Rocque, Warren, Reed, Steven I, Tainer, John A

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Dual Inhibition of Human Type 4 Phosphodiesterase Isostates by (R,R)-(±)-Methyl 3-Acetyl-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-3- methyl-1-pyrrolidinecarboxylate von Tian, Gaochao, Rocque, Warren J, Wiseman, Jeffrey S, Thompson, Irene Z, Holmes, William D, Domanico, Paul L, Stafford, Jeffrey A, Feldman, Paul L, Luther, Michael A

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Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding von Rocque, Warren J., Holmes, William D., Patel, Indravadan R., Dougherty, Robert W., Ittoop, Olivia, Overton, Laurie, Hoffman, Christine R., Wisely, G.Bruce, Willard, Derril H., Luther, Michael A.

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Replication-Associated Activities of Purified Human Papillomavirus Type 11 E1 Helicase von Rocque, Warren J., Porter, David J.T., Barnes, Julie A., Dixon, Eric P., Lobe, David C., Su, Jui-Lan, Willard, Derril H., Gaillard, Richard, Condreay, J.Patrick, Clay, William C., Hoffman, Christine R., Overton, Laurie K., Pahel, Greg, Kost, Thomas A., Phelps, William C.

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