Passive immunization reduces behavioral and neuropathological deficits in an alpha-synuclein transgenic model of Lewy body disease von Masliah, Eliezer, Rockenstein, Edward, Mante, Michael, Crews, Leslie, Spencer, Brian, Adame, Anthony, Patrick, Christina, Trejo, Margarita, Ubhi, Kiren, Rohn, Troy T, Mueller-Steiner, Sarah, Seubert, Peter, Barbour, Robin, McConlogue, Lisa, Buttini, Manuel, Games, Dora, Schenk, Dale

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AL amyloid imaging and therapy with a monoclonal antibody to a cryptic epitope on amyloid fibrils von Wall, Jonathan S, Kennel, Stephen J, Williams, Angela, Richey, Tina, Stuckey, Alan, Huang, Ying, Macy, Sallie, Donnell, Robert, Barbour, Robin, Seubert, Peter, Schenk, Dale

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Red Blood Cells Are the Major Source of Alpha-Synuclein in Blood von Barbour, Robin, Kling, Kristin, Anderson, John P., Banducci, Kelly, Cole, Tracy, Diep, Linnea, Fox, Michael, Goldstein, Jason M., Soriano, Ferdie, Seubert, Peter, Chilcote, Tamie J.

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Epitope and Isotype Specificities of Antibodies to β-Amyloid Peptide for Protection against Alzheimer's Disease-like Neuropathology von Bard, Frédérique, Barbour, Robin, Cannon, Catherine, Carretto, Robert, Fox, Michael, Games, Dora, Guido, Teresa, Hoenow, Kathleen, Hu, Kang, Johnson-Wood, Kelly, Khan, Karen, Kholodenko, Dora, Lee, Celeste, Lee, Mike, Motter, Ruth, Nguyen, Minh, Reed, Amanda, Schenk, Dale, Tang, Pearl, Vasquez, Nicki, Seubert, Peter, Yednock, Ted

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Anti-Mcam Monoclonal Antibody PRX003 Inhibits the Unique Migratory Potential of Pathogenic IL-17–Producing T Cells von Flanagan, Kenneth, Tam, Stephen J, Li, Lauri, Dolan, Philip J, Barbour, Robin M, Higaki, Jeffrey N, Liu, Yue, Nijjar, Tarlochan, Skov, Michael, Zago, Wagner, Yednock, Ted A, Kinney, Gene F, Ness, Dan

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Dual Amyloid Beta/Tau Vaccine PRX123 Surrogate Results in Robust Clearance of Amyloid Plaques in Brains of Aggressive APP/PS1 Mouse Model (P7-9.015) von Barbour, Robin, Tourino, Clara, Trumble, Alyssa, Louie, LeeAnn, Kinney, Gene, Zago, Wagner, Campbell, Brian

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Systematic Assessment of 10 Biomarker Candidates Focusing on α‐Synuclein‐Related Disorders von Schulz, Isabel, Kruse, Niels, Gera, Roland G., Kremer, Thomas, Cedarbaum, Jesse, Barbour, Robin, Zago, Wagner, Schade, Sebastian, Otte, Birgit, Bartl, Michael, Hutten, Samantha J., Trenkwalder, Claudia, Mollenhauer, Brit

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Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models von Games, Dora, Valera, Elvira, Spencer, Brian, Rockenstein, Edward, Mante, Michael, Adame, Anthony, Patrick, Christina, Ubhi, Kiren, Nuber, Silke, Sacayon, Patricia, Zago, Wagner, Seubert, Peter, Barbour, Robin, Schenk, Dale, Masliah, Eliezer

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Detection of Phosphorylated Ser in Fetal Tau, Adult Tau, and Paired Helical Filament Tau von Peter Seubert, Madhumalti Mawal-Dewan, Robin Barbour, Ross Jakes, Michel Goedert, Gail V. W. Johnson, Joel M. Litersky, Dale Schenk, Ivan Lieberburg, John Q. Trojanowski, Virginia M.-Y. Lee

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Immunological response to dual Aβ/Tau vaccine PRX123 surrogate and effects on brain amyloid plaques in rapidly depositing transgenic animal model von Tourino, Clara, Trumble, Alyssa, Louie, LeeAnn, Barbour, Robin M., Kinney, Gene G., Campbell, Brian, Zago, Wagner M.

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The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy von Moors, Tim E., Maat, Christina A., Niedieker, Daniel, Mona, Daniel, Petersen, Dennis, Timmermans-Huisman, Evelien, Kole, Jeroen, El-Mashtoly, Samir F., Spycher, Liz, Zago, Wagner, Barbour, Robin, Mundigl, Olaf, Kaluza, Klaus, Huber, Sylwia, Hug, Melanie N., Kremer, Thomas, Ritter, Mirko, Dziadek, Sebastian, Geurts, Jeroen J. G., Gerwert, Klaus, Britschgi, Markus, van de Berg, Wilma D. J.

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Axonopathy in an α -Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α -Synuclein von Games, Dora, Seubert, Peter, Rockenstein, Edward, Patrick, Christina, Trejo, Margarita, Ubhi, Kiren, Ettle, Benjamin, Ghassemiam, Majid, Barbour, Robin, Schenk, Dale, Nuber, Silke, Masliah, Eliezer

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Development of a dual Aβ‐tau vaccine for the prevention of Alzheimer’s disease von Barbour, Robin M, Bard, Frederique, Elmaarouf, Abderrahman, Louie, LeeAnn, Prill, Heather, Thomas, Kimberly, Kinney, Gene G, Zago, Wagner M

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Phosphorylation of Ser-129 Is the Dominant Pathological Modification of α-Synuclein in Familial and Sporadic Lewy Body Disease von Anderson, John P., Walker, Donald E., Goldstein, Jason M., de Laat, Rian, Banducci, Kelly, Caccavello, Russell J., Barbour, Robin, Huang, Jiping, Kling, Kristin, Lee, Michael, Diep, Linnea, Keim, Pamela S., Shen, Xiaofeng, Chataway, Tim, Schlossmacher, Michael G., Seubert, Peter, Schenk, Dale, Sinha, Sukanto, Gai, Wei Ping, Chilcote, Tamie J.

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Online monitoring and control of upstream cell culture process using 1D and 2D‐LC with SegFlow interface von Chemmalil, Letha, Wasalathanthri, Dhanuka P., Zhang, Xin, Kuang, June, Shao, Chun, Barbour, Robin, Bhavsar, Sohil, Prabhakar, Tanushree, Knihtila, Ryan, West, Jay, Puri, Neha, McHugh, Kyle, Rehmann, Matthew S., He, Qin, Xu, Jianlin, Borys, Michael C., Ding, Julia, Li, Zhengjian

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Anti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy von Spencer, Brian, Valera, Elvira, Rockenstein, Edward, Overk, Cassia, Mante, Michael, Adame, Anthony, Zago, Wagner, Seubert, Peter, Barbour, Robin, Schenk, Dale, Games, Dora, Rissman, Robert A, Masliah, Eliezer

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Immunotherapy reduces vascular amyloid-beta in PDAPP mice von Schroeter, Sally, Khan, Karen, Barbour, Robin, Doan, Minhtam, Chen, Ming, Guido, Terry, Gill, Davinder, Basi, Guriqbal, Schenk, Dale, Seubert, Peter, Games, Dora

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Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease von Bard, Frédérique, Cannon, Catherine, Barbour, Robin, Burke, Rae-Lyn, Games, Dora, Grajeda, Henry, Guido, Teresa, Hu, Kang, Huang, Jiping, Johnson-Wood, Kelly, Khan, Karen, Kholodenko, Dora, Lee, Mike, Lieberburg, Ivan, Motter, Ruth, Nguyen, Minh, Soriano, Ferdie, Vasquez, Nicki, Weiss, Kim, Welch, Brent, Seubert, Peter, Schenk, Dale, Yednock, Ted

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Abstract 464: Novel Anti-Medin Antibodies Detect Medin Amyloid Deposits in the Aorta of Patients with Thoracic Aneurysms or Marfan Syndrome von Shughrue, Paul, Alexander, Lana, Higaki, Jeffrey, Barbour, Robin, Salmans, Joshua, Schenk, Dale, Kinney, Gene G.

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Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease von Buttini, Manuel, Masliah, Eliezer, Barbour, Robin, Grajeda, Henry, Motter, Ruth, Johnson-Wood, Kelly, Khan, Karen, Seubert, Peter, Freedman, Stephen, Schenk, Dale, Games, Dora

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