MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition von Coll, Rebecca C., Hill, James R., Day, Christopher J., Zamoshnikova, Alina, Boucher, Dave, Massey, Nicholas L., Chitty, Jessica L., Fraser, James A., Jennings, Michael P., Robertson, Avril A. B., Schroder, Kate

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Human Monocytes Engage an Alternative Inflammasome Pathway von Gaidt, Moritz M., Ebert, Thomas S., Chauhan, Dhruv, Schmidt, Tobias, Schmid-Burgk, Jonathan L., Rapino, Francesca, Robertson, Avril A.B., Cooper, Matthew A., Graf, Thomas, Hornung, Veit

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NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5 von Baker, Paul J., Boucher, Dave, Bierschenk, Damien, Tebartz, Christina, Whitney, Paul G., D'Silva, Damian B., Tanzer, Maria C., Monteleone, Mercedes, Robertson, Avril A. B., Cooper, Matthew A., Alvarez‐Diaz, Silvia, Herold, Marco J., Bedoui, Sammy, Schroder, Kate, Masters, Seth L.

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DNA Repair in Mammalian Cells von Robertson, A. B, Klungland, A, Rognes, T, Leiros, I

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Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice von Krishnan, S M, Dowling, J K, Ling, Y H, Diep, H, Chan, C T, Ferens, D, Kett, M M, Pinar, A, Samuel, C S, Vinh, A, Arumugam, T V, Hewitson, T D, Kemp‐Harper, B K, Robertson, A A B, Cooper, M A, Latz, E, Mansell, A, Sobey, C G, Drummond, G R

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Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis von Hill, James R., Robertson, Avril A. B.

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Natural product and natural product derived drugs in clinical trials von Butler, Mark S, Robertson, Avril A B, Cooper, Matthew A

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Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration von Wooff, Yvette, Fernando, Nilisha, Wong, Josephine H. C., Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Robertson, Avril A. B., Doyle, Sarah L., Man, Si Ming, Natoli, Riccardo

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MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice von Perera, Agampodi Promoda, Fernando, Ruchira, Shinde, Tanvi, Gundamaraju, Rohit, Southam, Benjamin, Sohal, Sukhwinder Singh, Robertson, Avril A. B., Schroder, Kate, Kunde, Dale, Eri, Rajaraman

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Author Correction: Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration von Wooff, Yvette, Fernando, Nilisha, Wong, Josephine H. C., Dietrich, Catherine, Aggio-Bruce, Riemke, Chu-Tan, Joshua A., Robertson, Avril A. B., Doyle, Sarah L., Man, Si Ming, Natoli, Riccardo

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases von Coll, Rebecca C, Robertson, Avril A B, Chae, Jae Jin, Higgins, Sarah C, Muñoz-Planillo, Raúl, Inserra, Marco C, Vetter, Irina, Dungan, Lara S, Monks, Brian G, Stutz, Andrea, Croker, Daniel E, Butler, Mark S, Haneklaus, Moritz, Sutton, Caroline E, Núñez, Gabriel, Latz, Eicke, Kastner, Daniel L, Mills, Kingston H G, Masters, Seth L, Schroder, Kate, Cooper, Matthew A, O'Neill, Luke A J

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The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins von Deora, Vandana, Lee, John D., Albornoz, Eduardo A., McAlary, Luke, Jagaraj, Cyril J., Robertson, Avril A. B., Atkin, Julie D., Cooper, Matthew A., Schroder, Kate, Yerbury, Justin J., Gordon, Richard, Woodruff, Trent M.

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Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension von Krishnan, Shalini M, Ling, Yeong H, Huuskes, Brooke M, Ferens, Dorota M, Saini, Narbada, Chan, Christopher T, Diep, Henry, Kett, Michelle M, Samuel, Chrishan S, Kemp-Harper, Barbara K, Robertson, Avril A B, Cooper, Matthew A, Peter, Karlheinz, Latz, Eicke, Mansell, Ashley S, Sobey, Christopher G, Drummond, Grant R, Vinh, Antony

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Characterization and inhibition of inflammasome responses in severe and non-severe asthma von Horvat, Jay C, Kim, Richard Y, Weaver, Natasha, Augood, Christopher, Brown, Alexandra C, Donovan, Chantal, Dupre, Pierrick, Gunawardhana, Lakshitha, Mayall, Jemma R, Hansbro, Nicole G, Robertson, Avril A. B, O'Neill, Luke A. J, Cooper, Matthew A, Holliday, Elizabeth G, Hansbro, Philip M, Gibson, Peter G

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The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype von Basiorka, Ashley A., McGraw, Kathy L., Eksioglu, Erika A., Chen, Xianghong, Johnson, Joseph, Zhang, Ling, Zhang, Qing, Irvine, Brittany A., Cluzeau, Thomas, Sallman, David A., Padron, Eric, Komrokji, Rami, Sokol, Lubomir, Coll, Rebecca C., Robertson, Avril A.B., Cooper, Matthew A., Cleveland, John L., O'Neill, Luke A., Wei, Sheng, List, Alan F.

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Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction von Greenhill, Claire J, Jones, Gareth W, Nowell, Mari A, Newton, Zarabeth, Harvey, Ann K, Moideen, Abdul N, Collins, Fraser L, Bloom, Anja C, Coll, Rebecca C, Robertson, Avril A B, Cooper, Matthew A, Rosas, Marcela, Taylor, Philip R, O'Neill, Luke A, Humphreys, Ian R, Williams, Anwen S, Jones, Simon A

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Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection von Tucey, Timothy M., Verma, Jiyoti, Olivier, Francios A. B., Lo, Tricia L., Robertson, Avril A. B., Naderer, Thomas, Traven, Ana

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NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice von Mridha, Auvro R, Wree, Alexander, Robertson, Avril A.B, Yeh, Matthew M, Johnson, Casey D, Van Rooyen, Derrick M, Haczeyni, Fahrettin, Teoh, Narci C.-H, Savard, Christopher, Ioannou, George N, Masters, Seth L, Schroder, Kate, Cooper, Matthew A, Feldstein, Ariel E, Farrell, Geoffrey C

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Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma von Kim, Richard Y, Pinkerton, James W, Essilfie, Ama T, Robertson, Avril A B, Baines, Katherine J, Brown, Alexandra C, Mayall, Jemma R, Ali, M Khadem, Starkey, Malcolm R, Hansbro, Nicole G, Hirota, Jeremy A, Wood, Lisa G, Simpson, Jodie L, Knight, Darryl A, Wark, Peter A, Gibson, Peter G, O'Neill, Luke A J, Cooper, Matthew A, Horvat, Jay C, Hansbro, Philip M

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Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice von Fuster, José J., MacLauchlan, Susan, Zuriaga, María A., Polackal, Maya N., Ostriker, Allison C., Chakraborty, Raja, Wu, Chia-Ling, Sano, Soichi, Muralidharan, Sujatha, Rius, Cristina, Vuong, Jacqueline, Jacob, Sophia, Muralidhar, Varsha, Robertson, Avril A. B., Cooper, Matthew A., Andrés, Vicente, Hirschi, Karen K., Martin, Kathleen A., Walsh, Kenneth

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