Hypermutation in human cancer genomes: footprints and mechanisms von Roberts, Steven A., Gordenin, Dmitry A.

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Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions von Roberts, Steven A., Sterling, Joan, Thompson, Cole, Harris, Shawn, Mav, Deepak, Shah, Ruchir, Klimczak, Leszek J., Kryukov, Gregory V., Malc, Ewa, Mieczkowski, Piotr A., Resnick, Michael A., Gordenin, Dmitry A.

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APOBEC3A is a prominent cytidine deaminase in breast cancer von Cortez, Luis M, Brown, Amber L, Dennis, Madeline A, Collins, Christopher D, Brown, Alexander J, Mitchell, Debra, Mertz, Tony M, Roberts, Steven A

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Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks von Wyatt, David W., Feng, Wanjuan, Conlin, Michael P., Yousefzadeh, Matthew J., Roberts, Steven A., Mieczkowski, Piotr, Wood, Richard D., Gupta, Gaorav P., Ramsden, Dale A.

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Mechanistic basis for microhomology identification and genome scarring by polymerase theta von Carvajal-Garcia, Juan, Cho, Jang-Eun, Carvajal-Garcia, Pablo, Feng, Wanjuan, Wood, Richard D., Sekelsky, Jeff, Gupta, Gaorav P., Roberts, Steven A., Ramsden, Dale A.

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Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution von Mao, Peng, Smerdon, Michael J., Roberts, Steven A., Wyrick, John J.

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Analysis of Drosophila STING Reveals an Evolutionarily Conserved Antimicrobial Function von Martin, Marina, Hiroyasu, Aoi, Guzman, R. Marena, Roberts, Steven A., Goodman, Alan G.

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APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication von Hoopes, James I., Cortez, Luis M., Mertz, Tony M., Malc, Ewa P., Mieczkowski, Piotr A., Roberts, Steven A.

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An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers von Chan, Kin, Roberts, Steven A, Klimczak, Leszek J, Sterling, Joan F, Saini, Natalie, Malc, Ewa P, Kim, Jaegil, Kwiatkowski, David J, Fargo, David C, Mieczkowski, Piotr A, Getz, Gad, Gordenin, Dmitry A

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ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma von Mao, Peng, Brown, Alexander J., Esaki, Shingo, Lockwood, Svetlana, Poon, Gregory M. K., Smerdon, Michael J., Roberts, Steven A., Wyrick, John J.

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Characterization of sequence contexts that favor alternative end joining at Cas9-induced double-strand breaks von Hanscom, Terrence, Woodward, Nicholas, Batorsky, Rebecca, Brown, Alexander J, Roberts, Steven A, McVey, Mitch

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Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis von Sakofsky, Cynthia J., Roberts, Steven A., Malc, Ewa, Mieczkowski, Piotr A., Resnick, Michael A., Gordenin, Dmitry A., Malkova, Anna

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Nucleosome positions establish an extended mutation signature in melanoma von Brown, Alexander J, Mao, Peng, Smerdon, Michael J, Wyrick, John J, Roberts, Steven A

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Single-stranded DNA binding proteins influence APOBEC3A substrate preference von Brown, Amber L., Collins, Christopher D., Thompson, Secily, Coxon, Margo, Mertz, Tony M., Roberts, Steven A.

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Microfabricated blood vessels undergo neoangiogenesis von DiVito, Kyle A, Daniele, Michael A, Roberts, Steven A, Ligler, Frances S, Adams, André A

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The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts von Saini, Natalie, Roberts, Steven A, Klimczak, Leszek J, Chan, Kin, Grimm, Sara A, Dai, Shuangshuang, Fargo, David C, Boyer, Jayne C, Kaufmann, William K, Taylor, Jack A, Lee, Eunjung, Cortes-Ciriano, Isidro, Park, Peter J, Schurman, Shepherd H, Malc, Ewa P, Mieczkowski, Piotr A, Gordenin, Dmitry A

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Sweet Substrate: A Polysaccharide Nanocomposite for Conformal Electronic Decals von Daniele, Michael A., Knight, Adrian J., Roberts, Steven A., Radom, Kathryn, Erickson, Jeffrey S.

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Contributions of replicative and translesion DNA polymerases to mutagenic bypass of canonical and atypical UV photoproducts von Vandenberg, Brittany N., Laughery, Marian F., Cordero, Cameron, Plummer, Dalton, Mitchell, Debra, Kreyenhagen, Jordan, Albaqshi, Fatimah, Brown, Alexander J., Mieczkowski, Piotr A., Wyrick, John J., Roberts, Steven A.

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APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions von Kazanov, Marat D., Roberts, Steven A., Polak, Paz, Stamatoyannopoulos, John, Klimczak, Leszek J., Gordenin, Dmitry A., Sunyaev, Shamil R.

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Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent von Chan, Kin, Sterling, Joan F, Roberts, Steven A, Bhagwat, Ashok S, Resnick, Michael A, Gordenin, Dmitry A

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