The SWI/SNF complex in cancer — biology, biomarkers and therapy von Mittal, Priya, Roberts, Charles W. M.

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SWI/SNF nucleosome remodellers and cancer von Roberts, Charles W. M, Wilson, Boris G

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Molecular Pathways: SWI/SNF (BAF) Complexes Are Frequently Mutated in Cancer—Mechanisms and Potential Therapeutic Insights von XIAOFENG WANG, HASWELL, Jeffrey R, ROBERTS, Charles W. M

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ARID1B is a specific vulnerability in ARID1A-mutant cancers von Helming, Katherine C, Wang, Xiaofeng, Wilson, Boris G, Vazquez, Francisca, Haswell, Jeffrey R, Manchester, Haley E, Kim, Youngha, Kryukov, Gregory V, Ghandi, Mahmoud, Aguirre, Andrew J, Jagani, Zainab, Wang, Zhong, Garraway, Levi A, Hahn, William C, Roberts, Charles W M

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BRD9 defines a SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors von Wang, Xiaofeng, Wang, Su, Troisi, Emma C., Howard, Thomas P., Haswell, Jeffrey R., Wolf, Bennett K., Hawk, William H., Ramos, Pilar, Oberlick, Elaine M., Tzvetkov, Evgeni P., Ross, Aaron, Vazquez, Francisca, Hahn, William C., Park, Peter J., Roberts, Charles W. M.

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Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation von Wilson, Boris G., Helming, Katherine C., Wang, Xiaofeng, Kim, Youngha, Vazquez, Francisca, Jagani, Zainab, Hahn, William C., Roberts, Charles W. M.

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Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters von Tolstorukov, Michael Y., Sansam, Courtney G., Lu, Ping, Koellhoffer, Edward C., Helming, Katherine C., Alver, Burak H., Tillman, Erik J., Evans, Julia A., Wilson, Boris G., Park, Peter J., Roberts, Charles W. M.

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PHF6 cooperates with SWI/SNF complexes to facilitate transcriptional progression von Mittal, Priya, Myers, Jacquelyn A., Carter, Raymond D., Radko-Juettner, Sandi, Malone, Hayden A., Rosikiewicz, Wojciech, Robertson, Alexis N., Zhu, Zhexin, Narayanan, Ishwarya V., Hansen, Baranda S., Parrish, Meadow, Bhanu, Natarajan V., Mobley, Robert J., Rehg, Jerold E., Xu, Beisi, Drosos, Yiannis, Pruett-Miller, Shondra M., Ljungman, Mats, Garcia, Benjamin A., Wu, Gang, Partridge, Janet F., Roberts, Charles W. M.

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Chromatin remodellers as therapeutic targets von Malone, Hayden A., Roberts, Charles W. M.

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The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers von Alver, Burak H., Kim, Kimberly H., Lu, Ping, Wang, Xiaofeng, Manchester, Haley E., Wang, Weishan, Haswell, Jeffrey R., Park, Peter J., Roberts, Charles W. M.

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Mutational processes shape the landscape of TP53 mutations in human cancer von Giacomelli, Andrew O., Yang, Xiaoping, Lintner, Robert E., McFarland, James M., Duby, Marc, Kim, Jaegil, Howard, Thomas P., Takeda, David Y., Ly, Seav Huong, Kim, Eejung, Gannon, Hugh S., Hurhula, Brian, Sharpe, Ted, Goodale, Amy, Fritchman, Briana, Steelman, Scott, Vazquez, Francisca, Tsherniak, Aviad, Aguirre, Andrew J., Doench, John G., Piccioni, Federica, Roberts, Charles W. M., Meyerson, Matthew, Getz, Gad, Johannessen, Cory M., Root, David E., Hahn, William C.

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Developmental origins shape the paediatric cancer genome von Chen, Xiaolong, Yang, Wentao, Roberts, Charles W. M., Zhang, Jinghui

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Author Correction: Developmental origins shape the paediatric cancer genome von Chen, Xiaolong, Yang, Wentao, Roberts, Charles W. M., Zhang, Jinghui

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SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation von Wang, Xiaofeng, Lee, Ryan S, Alver, Burak H, Haswell, Jeffrey R, Wang, Su, Mieczkowski, Jakub, Drier, Yotam, Gillespie, Shawn M, Archer, Tenley C, Wu, Jennifer N, Tzvetkov, Evgeni P, Troisi, Emma C, Pomeroy, Scott L, Biegel, Jaclyn A, Tolstorukov, Michael Y, Bernstein, Bradley E, Park, Peter J, Roberts, Charles W M

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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma von Perry, Jennifer A, Kiezun, Adam, Tonzi, Peter, Van Allen, Eliezer M, Carter, Scott L, Baca, Sylvan C, Cowley, Glenn S, Bhatt, Ami S, Rheinbay, Esther, Pedamallu, Chandra Sekhar, Helman, Elena, Taylor-Weiner, Amaro, McKenna, Aaron, DeLuca, David S, Lawrence, Michael S, Ambrogio, Lauren, Sougnez, Carrie, Sivachenko, Andrey, Walensky, Loren D, Wagle, Nikhil, Mora, Jaume, de Torres, Carmen, Lavarino, Cinzia, Dos Santos Aguiar, Simone, Yunes, Jose Andres, Brandalise, Silvia Regina, Mercado-Celis, Gabriela Elisa, Melendez-Zajgla, Jorge, Cárdenas-Cardós, Rocío, Velasco-Hidalgo, Liliana, Roberts, Charles W M, Garraway, Levi A, Rodriguez-Galindo, Carlos, Gabriel, Stacey B, Lander, Eric S, Golub, Todd R, Orkin, Stuart H, Getz, Gad, Janeway, Katherine A

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Atypical teratoid/rhabdoid tumors-current concepts, advances in biology, and potential future therapies von Frühwald, Michael C, Biegel, Jaclyn A, Bourdeaut, Franck, Roberts, Charles W M, Chi, Susan N

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Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers von Hoffman, Gregory R., Rahal, Rami, Buxton, Frank, Xiang, Kay, McAllister, Gregory, Frias, Elizabeth, Bagdasarian, Linda, Huber, Janina, Lindeman, Alicia, Chen, Dongshu, Romero, Rodrigo, Ramadan, Nadire, Phadke, Tanushree, Haas, Kristy, Jaskelioff, Mariela, Wilson, Boris G., Meyer, Matthew J., Saenz-Vash, Veronica, Zhai, Huili, Myer, Vic E., Porter, Jeffrey A., Keen, Nicholas, McLaughlin, Margaret E., Mickanin, Craig, Roberts, Charles W. M., Stegmeier, Frank, Jagani, Zainab

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Metagene projection for cross-platform, cross-species characterization of global transcriptional states von Tamayo, Pablo, Scanfeld, Daniel, Ebert, Benjamin L, Gillette, Michael A, Roberts, Charles W.M, Mesirov, Jill P

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Targeting EZH2 in cancer von Kim, Kimberly H, Roberts, Charles W M

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Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity von Yin, Jie, Leavenworth, Jianmei W., Li, Yang, Luo, Qi, Xie, Huafeng, Liu, Xinhua, Huang, Shan, Yan, Han, Fu, Zheng, Zhang, Liyun Y., Zhang, Litao, Hao, Junwei, Wu, Xudong, Deng, Xianming, Roberts, Charles W. M., Orkin, Stuart H., Cantor, Harvey, Wang, Xi

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