The Role of Intra-Tumoral Heterogeneity and Its Clinical Relevance in Epithelial Ovarian Cancer Recurrence and Metastasis von Roberts, Cai M, Cardenas, Carlos, Tedja, Roslyn

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p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT von Yang-Hartwich, Yang, Tedja, Roslyn, Roberts, Cai M, Goodner-Bingham, Jamie, Cardenas, Carlos, Gurea, Marta, Sumi, Natalia J, Alvero, Ayesha B, Glackin, Carlotta A, Mor, Gil

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Shake It Up Baby Now: The Changing Focus on TWIST1 and Epithelial to Mesenchymal Transition in Cancer and Other Diseases von Mirjat, Dureali, Kashif, Muhammad, Roberts, Cai M

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Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models von Roberts, Cai M, Shahin, Sophia Allaf, Wen, Wei, Finlay, James B, Dong, Juyao, Wang, Ruining, Dellinger, Thanh H, Zink, Jeffrey I, Tamanoi, Fuyuhiko, Glackin, Carlotta A

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Pterostilbene Suppresses Ovarian Cancer Growth via Induction of Apoptosis and Blockade of Cell Cycle Progression Involving Inhibition of the STAT3 Pathway von Wen, Wei, Lowe, Gina, Roberts, Cai M, Finlay, James, Han, Ernest S, Glackin, Carlotta A, Dellinger, Thanh Hue

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Two Plasmid-Based Systems for CRISPR/Cas9 Mediated Knockout of Target Genes von Roberts, Cai M., Ratner, Elena S.

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Placenta-derived interferon-stimulated gene 20 controls ZIKA virus infection von Ding, Jiahui, Aldo, Paulomi, Roberts, Cai M, Stabach, Paul, Liu, Hong, You, Yuan, Qiu, Xuemin, Jeong, Jiwon, Maxwell, Anthony, Lindenbach, Brett, Braddock, Demetrios, Liao, Aihua, Mor, Gil

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RNA-Based TWIST1 Inhibition via Dendrimer Complex to Reduce Breast Cancer Cell Metastasis von Rossi, John J., Loeza, Joana, Lowe, Gina, Roberts, Cai M., Finlay, James, Glackin, Carlotta

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Mesoporous silica nanoparticle delivery of chemically modified siRNA against TWIST1 leads to reduced tumor burden von Finlay, James, DVM, Roberts, Cai M., BS, Dong, Juyao, PhD, Zink, Jeffrey I., PhD, Tamanoi, Fuyuhiko, PhD, Glackin, Carlotta A., PhD

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Protein kinase Cα–mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it von Tedja, Roslyn, Roberts, Cai M., Alvero, Ayesha B., Cardenas, Carlos, Yang-Hartwich, Yang, Spadinger, Sydney, Pitruzzello, Mary, Yin, Gang, Glackin, Carlotta A., Mor, Gil

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CBX7 binds the E-box to inhibit TWIST-1 function and inhibit tumorigenicity and metastatic potential von Li, Juanni, Alvero, Ayesha B., Nuti, Sudhakar, Tedja, Roslyn, Roberts, Cai M., Pitruzzello, Mary, Li, Yimin, Xiao, Qing, Zhang, Sai, Gan, Yaqi, Wu, Xiaoying, Mor, Gil, Yin, Gang

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TWIST1 drives cisplatin resistance and cell survival in an ovarian cancer model, via upregulation of GAS6, L1CAM, and Akt signalling von Roberts, Cai M., Tran, Michelle A., Pitruzzello, Mary C., Wen, Wei, Loeza, Joana, Dellinger, Thanh H., Mor, Gil, Glackin, Carlotta A.

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Transforming Growth Factor Beta and Epithelial to Mesenchymal Transition Alter Homologous Recombination Repair Gene Expression and Sensitize BRCA Wild-Type Ovarian Cancer Cells to... von Roberts, Cai M, Rojas-Alexandre, Mehida, Hanna, Ruth E, Lin, Z Ping, Ratner, Elena S

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Flow Cytometric Analyses of p53-Mediated Cell Cycle Arrest and Apoptosis in Cancer Cells von Al Zouabi, Nour N., Roberts, Cai M., Lin, Z. Ping, Ratner, Elena S.

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Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer von Wen, Wei, Lowe, Gina, Roberts, Cai M., Finlay, James, Han, Ernest S., Glackin, Carlotta A., Dellinger, Thanh H.

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Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target von Roberts, Cai M, Shahin, Sophia A, Loeza, Joana, Dellinger, Thanh H, Williams, John C, Glackin, Carlotta A

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Rad59 regulates association of Rad52 with DNA double‐strand breaks von Pannunzio, Nicholas R., Manthey, Glenn M., Liddell, Lauren C., Fu, Becky Xu Hua, Roberts, Cai M., Bailis, Adam M.

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Abstract TMIM-084: PKCα INDUCES TWIST1 PHOSPHORYLATION AT SERINE 144 AND PROMOTES EMT IN OVARIAN CANCER CELLS von Tedja, Roslyn, Roberts, Cai, Cardenas, Carlos, Alvero, Ayesha B., Pitruzzello, Mary, Yang-Hartwich, Yang, Glackin, Carlotta, Mor, Gil G.

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Abstract A02: CBX7 binds TWIST-1’s E-box to inhibit TWIST-1 function and curtail tumorigenecity and metastatic potential in ovarian cancer von Li, Juanni, Alvero, Ayesha B, Nuti, Sudhakar, Tedja, Roslyn, Roberts, Cai M., Pitruzzello, Mary, Li, Yimin, Xiao, Qing, Zhang, Sai, Gan, Yaqi, Mor, Gil, Yin, Gang

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Abstract 1969: PKCα-induced Twist1 phosphorylation is a novel regulator of Twist1 stabilization von Tedja, Roslyn, Alvero, Ayesha B., Cardenas, Carlos, Pitruzzello, Mary, Yin, Gang, Yang-Hartwich, Yang, Roberts, Cai, Glackin, Carlotta, Mor, Gil G.

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