Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors von Sykes, David A., Moore, Holly, Stott, Lisa, Holliday, Nicholas, Javitch, Jonathan A., Lane, J. Robert, Charlton, Steven J.

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A kinetic view of GPCR allostery and biased agonism von Lane, J Robert, May, Lauren T, Parton, Robert G, Sexton, Patrick M, Christopoulos, Arthur

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Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists von Gillis, Alexander, Gondin, Arisbel B, Kliewer, Andrea, Sanchez, Julie, Lim, Herman D, Alamein, Claudia, Manandhar, Preeti, Santiago, Marina, Fritzwanker, Sebastian, Schmiedel, Frank, Katte, Timothy A, Reekie, Tristan, Grimsey, Natasha L, Kassiou, Michael, Kellam, Barrie, Krasel, Cornelius, Halls, Michelle L, Connor, Mark, Lane, J Robert, Schulz, Stefan, Christie, Macdonald J, Canals, Meritxell

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The role of kinetic context in apparent biased agonism at GPCRs von Klein Herenbrink, Carmen, Sykes, David A., Donthamsetti, Prashant, Canals, Meritxell, Coudrat, Thomas, Shonberg, Jeremy, Scammells, Peter J., Capuano, Ben, Sexton, Patrick M., Charlton, Steven J., Javitch, Jonathan A., Christopoulos, Arthur, Lane, J. Robert

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New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling von Mann, Anika, Keen, Alastair C., Mark, Hanka, Dasgupta, Pooja, Javitch, Jonathan A., Canals, Meritxell, Schulz, Stefan, Robert Lane, J.

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Bridging the gap: bitopic ligands of G-protein-coupled receptors von Lane, J. Robert, Sexton, Patrick M, Christopoulos, Arthur

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Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10 von Lim, Herman D, Lane, J Robert, Canals, Meritxell, Stone, Martin J

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Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs von Dror, Ron O., Green, Hillary F., Valant, Celine, Borhani, David W., Valcourt, James R., Pan, Albert C., Arlow, Daniel H., Canals, Meritxell, Lane, J. Robert, Rahmani, Raphaël, Baell, Jonathan B., Sexton, Patrick M., Christopoulos, Arthur, Shaw, David E.

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Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivation von Donthamsetti, Prashant, Gallo, Eduardo F., Buck, David C., Stahl, Edward L., Zhu, Ying, Lane, J. Robert, Bohn, Laura M., Neve, Kim A., Kellendonk, Christoph, Javitch, Jonathan A.

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The Best of Both Worlds? Bitopic Orthosteric/Allosteric Ligands of G Protein―Coupled Receptors von VALANT, Celine, ROBERT LANE, J, SEXTON, Patrick M, CHRISTOPOULOS, Arthur

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Biased Agonism at G Protein-Coupled Receptors: The Promise and the Challenges-A Medicinal Chemistry Perspective von Shonberg, Jeremy, Lopez, Laura, Scammells, Peter J., Christopoulos, Arthur, Capuano, Ben, Lane, J. Robert

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Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1 von Sanchez, Julie, e Huma, Zil, Lane, J. Robert, Liu, Xuyu, Bridgford, Jessica L., Payne, Richard J., Canals, Meritxell, Stone, Martin J.

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β2 -adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer von Chang, Aeson, Le, Caroline P, Walker, Adam K, Creed, Sarah J, Pon, Cindy K, Albold, Sabine, Carroll, Dominic, Halls, Michelle L, Robert Lane, J, Riedel, Bernhard, Ferrari, Davide, Sloan, Erica K

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A new mechanism of allostery in a G protein–coupled receptor dimer von Lane, J Robert, Donthamsetti, Prashant, Shonberg, Jeremy, Draper-Joyce, Christopher J, Dentry, Samuel, Michino, Mayako, Shi, Lei, López, Laura, Scammells, Peter J, Capuano, Ben, Sexton, Patrick M, Javitch, Jonathan A, Christopoulos, Arthur

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Influence of Chemokine N-Terminal Modification on Biased Agonism at the Chemokine Receptor CCR1 von Sanchez, Julie, Lane, J Robert, Canals, Meritxell, Stone, Martin J

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Mechanistic Insights into Allosteric Structure-Function Relationships at the M1 Muscarinic Acetylcholine Receptor von Abdul-Ridha, Alaa, Lane, J.Robert, Mistry, Shailesh N., López, Laura, Sexton, Patrick M., Scammells, Peter J., Christopoulos, Arthur, Canals, Meritxell

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The differential actions of clozapine and other antipsychotic drugs on the translocation of dopamine D2 receptors to the cell surface von Schrader, Joseph M., Irving, Craig M., Octeau, J. Christopher, Christian, Joseph A., Aballo, Timothy J., Kareemo, Dean J., Conti, Joseph, Camberg, Jodi L., Lane, J. Robert, Javitch, Jonathan A., Kovoor, Abraham

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A Structure–Activity Analysis of Biased Agonism at the Dopamine D2 Receptor von Shonberg, Jeremy, Herenbrink, Carmen Klein, López, Laura, Christopoulos, Arthur, Scammells, Peter J, Capuano, Ben, Lane, J. Robert

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Enantioenriched Positive Allosteric Modulators Display Distinct Pharmacology at the Dopamine D1 Receptor von Fyfe, Tim J., Scammells, Peter J., Lane, J. Robert, Capuano, Ben

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Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor von Thompson, Georgina L., Lane, J. Robert, Coudrat, Thomas, Sexton, Patrick M., Christopoulos, Arthur, Canals, Meritxell

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