De Novo Gene Disruptions in Children on the Autistic Spectrum von Iossifov, Ivan, Ronemus, Michael, Levy, Dan, Wang, Zihua, Hakker, Inessa, Rosenbaum, Julie, Yamrom, Boris, Lee, Yoon-ha, Narzisi, Giuseppe, Leotta, Anthony, Kendall, Jude, Grabowska, Ewa, Ma, Beicong, Marks, Steven, Rodgers, Linda, Stepansky, Asya, Troge, Jennifer, Andrews, Peter, Bekritsky, Mitchell, Pradhan, Kith, Ghiban, Elena, Kramer, Melissa, Parla, Jennifer, Demeter, Ryan, Fulton, Lucinda L., Fulton, Robert S., Magrini, Vincent J., Ye, Kenny, Darnell, Jennifer C., Darnell, Robert B., Mardis, Elaine R., Wilson, Richard K., Schatz, Michael C., McCombie, W. Richard, Wigler, Michael

Volltext

Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia von Klco, Jeffery M., Spencer, David H., Miller, Christopher A., Griffith, Malachi, Lamprecht, Tamara L., O’Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Fulton, Robert S., Eades, William C., Link, Daniel C., Graubert, Timothy A., Walter, Matthew J., Mardis, Elaine R., Dipersio, John F., Wilson, Richard K., Ley, Timothy J.

Volltext

High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy von Gubin, Matthew M., Esaulova, Ekaterina, Ward, Jeffrey P., Malkova, Olga N., Runci, Daniele, Wong, Pamela, Noguchi, Takuro, Arthur, Cora D., Meng, Wei, Alspach, Elise, Medrano, Ruan F.V., Fronick, Catrina, Fehlings, Michael, Newell, Evan W., Fulton, Robert S., Sheehan, Kathleen C.F., Oh, Stephen T., Schreiber, Robert D., Artyomov, Maxim N.

Volltext

Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification von Lalli, Matthew A, Langmade, Joshua S, Chen, Xuhua, Fronick, Catrina C, Sawyer, Christopher S, Burcea, Lauren C, Wilkinson, Michael N, Fulton, Robert S, Heinz, Michael, Buchser, William J, Head, Richard D, Mitra, Robi D, Milbrandt, Jeffrey

Volltext

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly von Schneider, Valerie A, Graves-Lindsay, Tina, Howe, Kerstin, Bouk, Nathan, Chen, Hsiu-Chuan, Kitts, Paul A, Murphy, Terence D, Pruitt, Kim D, Thibaud-Nissen, Françoise, Albracht, Derek, Fulton, Robert S, Kremitzki, Milinn, Magrini, Vincent, Markovic, Chris, McGrath, Sean, Steinberg, Karyn Meltz, Auger, Kate, Chow, William, Collins, Joanna, Harden, Glenn, Hubbard, Timothy, Pelan, Sarah, Simpson, Jared T, Threadgold, Glen, Torrance, James, Wood, Jonathan M, Clarke, Laura, Koren, Sergey, Boitano, Matthew, Peluso, Paul, Li, Heng, Chin, Chen-Shan, Phillippy, Adam M, Durbin, Richard, Wilson, Richard K, Flicek, Paul, Eichler, Evan E, Church, Deanna M

Volltext

A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation von Hsiao, Hsi-Min, Sapinoro, Ramil E, Thatcher, Thomas H, Croasdell, Amanda, Levy, Elizabeth P, Fulton, Robert A, Olsen, Keith C, Pollock, Stephen J, Serhan, Charles N, Phipps, Richard P, Sime, Patricia J

Volltext

Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes von Soh, Y Q Shirleen, Alföldi, Jessica, Pyntikova, Tatyana, Brown, Laura G, Graves, Tina, Minx, Patrick J, Fulton, Robert S, Kremitzki, Colin, Koutseva, Natalia, Mueller, Jacob L, Rozen, Steve, Hughes, Jennifer F, Owens, Elaine, Womack, James E, Murphy, William J, Cao, Qing, de Jong, Pieter, Warren, Wesley C, Wilson, Richard K, Skaletsky, Helen, Page, David C

Volltext

Evolution of symbiotic bacteria in the distal human intestine von Xu, Jian, Mahowald, Michael A, Ley, Ruth E, Lozupone, Catherine A, Hamady, Micah, Martens, Eric C, Henrissat, Bernard, Coutinho, Pedro M, Minx, Patrick, Latreille, Philippe, Cordum, Holland, Van Brunt, Andrew, Kim, Kyung, Fulton, Robert S, Fulton, Lucinda A, Clifton, Sandra W, Wilson, Richard K, Knight, Robin D, Gordon, Jeffrey I

Volltext

A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing von Petti, Allegra A., Williams, Stephen R., Miller, Christopher A., Fiddes, Ian T., Srivatsan, Sridhar N., Chen, David Y., Fronick, Catrina C., Fulton, Robert S., Church, Deanna M., Ley, Timothy J.

Volltext

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo von Shirai, Cara Lunn, Ley, James N., White, Brian S., Kim, Sanghyun, Tibbitts, Justin, Shao, Jin, Ndonwi, Matthew, Wadugu, Brian, Duncavage, Eric J., Okeyo-Owuor, Theresa, Liu, Tuoen, Griffith, Malachi, McGrath, Sean, Magrini, Vincent, Fulton, Robert S., Fronick, Catrina, O’Laughlin, Michelle, Graubert, Timothy A., Walter, Matthew J.

Volltext

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma von Wu, Gang, Diaz, Alexander K, Paugh, Barbara S, Rankin, Sherri L, Ju, Bensheng, Li, Yongjin, Zhu, Xiaoyan, Qu, Chunxu, Chen, Xiang, Zhang, Junyuan, Easton, John, Edmonson, Michael, Ma, Xiaotu, Lu, Charles, Nagahawatte, Panduka, Hedlund, Erin, Rusch, Michael, Pounds, Stanley, Lin, Tong, Onar-Thomas, Arzu, Huether, Robert, Kriwacki, Richard, Parker, Matthew, Gupta, Pankaj, Becksfort, Jared, Wei, Lei, Mulder, Heather L, Boggs, Kristy, Vadodaria, Bhavin, Yergeau, Donald, Russell, Jake C, Ochoa, Kerri, Fulton, Robert S, Fulton, Lucinda L, Jones, Chris, Boop, Frederick A, Broniscer, Alberto, Wetmore, Cynthia, Gajjar, Amar, Ding, Li, Mardis, Elaine R, Wilson, Richard K, Taylor, Michael R, Downing, James R, Ellison, David W, Zhang, Jinghui, Baker, Suzanne J

Volltext

Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases von Hoadley, Katherine A, Siegel, Marni B, Kanchi, Krishna L, Miller, Christopher A, Ding, Li, Zhao, Wei, He, Xiaping, Parker, Joel S, Wendl, Michael C, Fulton, Robert S, Demeter, Ryan T, Wilson, Richard K, Carey, Lisa A, Perou, Charles M, Mardis, Elaine R

Volltext

C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma von Parker, Matthew, Mohankumar, Kumarasamypet M., Punchihewa, Chandanamali, Weinlich, Ricardo, Dalton, James D., Li, Yongjin, Lee, Ryan, Tatevossian, Ruth G., Phoenix, Timothy N., Thiruvenkatam, Radhika, White, Elsie, Tang, Bo, Orisme, Wilda, Gupta, Kirti, Rusch, Michael, Chen, Xiang, Li, Yuxin, Nagahawhatte, Panduka, Hedlund, Erin, Finkelstein, David, Wu, Gang, Shurtleff, Sheila, Easton, John, Boggs, Kristy, Yergeau, Donald, Vadodaria, Bhavin, Mulder, Heather L., Becksfort, Jared, Gupta, Pankaj, Huether, Robert, Ma, Jing, Song, Guangchun, Gajjar, Amar, Merchant, Thomas, Boop, Frederick, Smith, Amy A., Ding, Li, Lu, Charles, Ochoa, Kerri, Zhao, David, Fulton, Robert S., Fulton, Lucinda L., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Green, Douglas R., Zhang, Jinghui, Ellison, David W., Gilbertson, Richard J.

Volltext

Harnessing Expressed Single Nucleotide Variation and Single Cell RNA Sequencing To Define Immune Cell Chimerism in the Rejecting Kidney Transplant von Malone, Andrew F, Wu, Haojia, Fronick, Catrina, Fulton, Robert, Gaut, Joseph P, Humphreys, Benjamin D

Volltext

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas von Zhang, Jinghui, Wu, Gang, Miller, Claudia P, Tatevossian, Ruth G, Dalton, James D, Tang, Bo, Orisme, Wilda, Punchihewa, Chandanamali, Parker, Matthew, Qaddoumi, Ibrahim, Boop, Fredrick A, Lu, Charles, Kandoth, Cyriac, Ding, Li, Lee, Ryan, Huether, Robert, Chen, Xiang, Hedlund, Erin, Nagahawatte, Panduka, Rusch, Michael, Boggs, Kristy, Cheng, Jinjun, Becksfort, Jared, Ma, Jing, Song, Guangchun, Li, Yongjin, Wei, Lei, Wang, Jianmin, Shurtleff, Sheila, Easton, John, Zhao, David, Fulton, Robert S, Fulton, Lucinda L, Dooling, David J, Vadodaria, Bhavin, Mulder, Heather L, Tang, Chunlao, Ochoa, Kerri, Mullighan, Charles G, Gajjar, Amar, Kriwacki, Richard, Sheer, Denise, Gilbertson, Richard J, Mardis, Elaine R, Wilson, Richard K, Downing, James R, Baker, Suzanne J, Ellison, David W

Volltext

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential von Wong, Terrence N., Miller, Christopher A., Jotte, Matthew R. M., Bagegni, Nusayba, Baty, Jack D., Schmidt, Amy P., Cashen, Amanda F., Duncavage, Eric J., Helton, Nichole M., Fiala, Mark, Fulton, Robert S., Heath, Sharon E., Janke, Megan, Luber, Kierstin, Westervelt, Peter, Vij, Ravi, DiPersio, John F., Welch, John S., Graubert, Timothy A., Walter, Matthew J., Ley, Timothy J., Link, Daniel C.

Volltext

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators von Bellott, Daniel W., Hughes, Jennifer F., Skaletsky, Helen, Brown, Laura G., Pyntikova, Tatyana, Cho, Ting-Jan, Koutseva, Natalia, Zaghlul, Sara, Graves, Tina, Rock, Susie, Kremitzki, Colin, Fulton, Robert S., Dugan, Shannon, Ding, Yan, Morton, Donna, Khan, Ziad, Lewis, Lora, Buhay, Christian, Wang, Qiaoyan, Watt, Jennifer, Holder, Michael, Lee, Sandy, Nazareth, Lynne, Alföldi, Jessica, Rozen, Steve, Muzny, Donna M., Warren, Wesley C., Gibbs, Richard A., Wilson, Richard K., Page, David C.

Volltext

Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma von Krysiak, Kilannin, Gomez, Felicia, White, Brian S., Matlock, Matthew, Miller, Christopher A., Trani, Lee, Fronick, Catrina C., Fulton, Robert S., Kreisel, Friederike, Cashen, Amanda F., Carson, Kenneth R., Berrien-Elliott, Melissa M., Bartlett, Nancy L., Griffith, Malachi, Griffith, Obi L., Fehniger, Todd A.

Volltext

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers von Govindan, Ramaswamy, Ding, Li, Griffith, Malachi, Subramanian, Janakiraman, Dees, Nathan D., Kanchi, Krishna L., Maher, Christopher A., Fulton, Robert, Fulton, Lucinda, Wallis, John, Chen, Ken, Walker, Jason, McDonald, Sandra, Bose, Ron, Ornitz, David, Xiong, Donghai, You, Ming, Dooling, David J., Watson, Mark, Mardis, Elaine R., Wilson, Richard K.

Volltext

CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression von Spencer, David H., Russler-Germain, David A., Ketkar, Shamika, Helton, Nichole M., Lamprecht, Tamara L., Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Heath, Sharon E., Shinawi, Marwan, Westervelt, Peter, Payton, Jacqueline E., Wartman, Lukas D., Welch, John S., Wilson, Richard K., Walter, Matthew J., Link, Daniel C., DiPersio, John F., Ley, Timothy J.

Volltext