International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors von Panula, Pertti, Chazot, Paul L., Cowart, Marlon, Gutzmer, Ralf, Leurs, Rob, Liu, Wai L.S., Stark, Holger, Thurmond, Robin L., Haas, Helmut L.

Volltext

The Landscape of Atypical and Eukaryotic Protein Kinases von Kanev, Georgi K., de Graaf, Chris, de Esch, Iwan J.P., Leurs, Rob, Würdinger, Thomas, Westerman, Bart A., Kooistra, Albert J.

Volltext

The clinical pharmacology of non-sedating antihistamines von Yanai, Kazuhiko, Yoshikawa, Takeo, Yanai, Ai, Nakamura, Tadaho, Iida, Tomomitsu, Leurs, Rob, Tashiro, Manabu

Volltext

KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space von van Linden, Oscar P. J., Kooistra, Albert J., Leurs, Rob, de Esch, Iwan J. P., de Graaf, Chris

Volltext

Structural Optimization of BIPPO Analogs as Potent Antimalarials von Zheng, Yang, Matheeussen, An, Maes, Louis, Caljon, Guy, Sterk, Geert Jan, Leurs, Rob

Volltext

KLIFS: a structural kinase-ligand interaction database von Kooistra, Albert J, Kanev, Georgi K, van Linden, Oscar P J, Leurs, Rob, de Esch, Iwan J P, de Graaf, Chris

Volltext

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time von Schuetz, Doris A., de Witte, Wilhelmus Egbertus Arnout, Wong, Yin Cheong, Knasmueller, Bernhard, Richter, Lars, Kokh, Daria B., Sadiq, S. Kashif, Bosma, Reggie, Nederpelt, Indira, Heitman, Laura H., Segala, Elena, Amaral, Marta, Guo, Dong, Andres, Dorothee, Georgi, Victoria, Stoddart, Leigh A., Hill, Steve, Cooke, Robert M., De Graaf, Chris, Leurs, Rob, Frech, Matthias, Wade, Rebecca C., de Lange, Elizabeth Cunera Maria, IJzerman, Adriaan P., Müller-Fahrnow, Anke, Ecker, Gerhard F.

Volltext

Structural basis of ligand recognition and design of antihistamines targeting histamine H4 receptor von Xia, Ruixue, Shi, Shuang, Xu, Zhenmei, Vischer, Henry F., Windhorst, Albert D., Qian, Yu, Duan, Yaning, Liang, Jiale, Chen, Kai, Zhang, Anqi, Guo, Changyou, Leurs, Rob, He, Yuanzheng

Volltext

Synthesis and Pharmacological Characterization of New Photocaged Agonists for Histamine H3 and H4 Receptors von Zheng, Yang, Gao, Meichun, Wijtmans, Maikel, Vischer, Henry F., Leurs, Rob

Volltext

CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells von Jähnichen, Sven, Blanchetot, Christophe, Maussang, David, Gonzalez-Pajuelo, Maria, Chow, Ken Y., Bosch, Leontien, De Vrieze, Sindi, Serruys, Benedikte, Ulrichts, Hans, Vandevelde, Wesly, Saunders, Michael, De Haard, Hans J., Schols, Dominique, Leurs, Rob, Vanlandschoot, Peter, Verrips, Theo, Smit, Martine J., Wells, James A.

Volltext

Development of novel fluorescent histamine H1-receptor antagonists to study ligand-binding kinetics in living cells von Stoddart, Leigh A., Vernall, Andrea J., Bouzo-Lorenzo, Monica, Bosma, Reggie, Kooistra, Albert J., de Graaf, Chris, Vischer, Henry F., Leurs, Rob, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.

Volltext

The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth von Heukers, Raimond, Fan, Tian Shu, de Wit, Raymond H., van Senten, Jeffrey R., De Groof, Timo W. M., Bebelman, Maarten P., Lagerweij, Tonny, Vieira, Joao, de Munnik, Sabrina M., Smits-de Vries, Laura, van Offenbeek, Jody, Rahbar, Afsar, van Hoorick, Diane, Söderberg-Naucler, Cecilia, Würdinger, Thomas, Leurs, Rob, Siderius, Marco, Vischer, Henry F., Smit, Martine J.

Volltext

Histamine H3 Receptor Isoforms: Insights from Alternative Splicing to Functional Complexity von Gao, Meichun, Ooms, Jasper F., Leurs, Rob, Vischer, Henry F.

Volltext

The histamine H3 receptor: from gene cloning to H3 receptor drugs von Leurs, Rob, Bakker, Remko A., Timmerman, Henk, de Esch, Iwan J. P.

Volltext

Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks von Kanev, Georgi K, Zhang, Yaran, Kooistra, Albert J, Bender, Andreas, Leurs, Rob, Bailey, David, Würdinger, Thomas, de Graaf, Chris, de Esch, Iwan J. P, Westerman, Bart A

Volltext

Histamine downregulates monocyte CCL2 production through the histamine H4 receptor von Dijkstra, Dorothea, MSc, Leurs, Rob, PhD, Chazot, Paul, PhD, Shenton, Fiona C., MSc, Stark, Holger, PhD, Werfel, Thomas, MD, Gutzmer, Ralf, MD

Volltext

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors von Ferrada, Carla, Moreno, Estefanía, Casadó, Vicent, Bongers, Gerold, Cortés, Antoni, Mallol, Josefa, Canela, Enric I, Leurs, Rob, Ferré, Sergi, Lluís, Carme, Franco, Rafael

Volltext

Short- and Long-Term Social Recognition Memory Are Differentially Modulated by Neuronal Histamine von Rani, Barbara, Silva-Marques, Bruna, Leurs, Rob, Passani, Maria Beatrice, Blandina, Patrizio, Provensi, Gustavo

Volltext

Ligand efficiency as a guide in fragment hit selection and optimization von Schultes, Sabine, de Graaf, Chris, Haaksma, Eric E.J., de Esch, Iwan J.P., Leurs, Rob, Krämer, Oliver

Volltext

Ubiquitination of CXCR7 controls receptor trafficking von Canals, Meritxell, Scholten, Danny J, de Munnik, Sabrina, Han, Mitchell K L, Smit, Martine J, Leurs, Rob

Volltext