Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation von ROACH, P. L, CLIFTON, I. J, HENSGENS, C. M. H, SHIBATA, N, SCHOFIELD, C. J, HAJDU, J, BALDWIN, J. E

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Inhibition of Yersinia pestis DNA adenine methyltransferase in vitro by a stibonic acid compound: identification of a potential novel class of antimicrobial agents von McKelvie, JC, Richards, MI, Harmer, JE, Milne, TS, Roach, PL, Oyston, PCF

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The reaction cycle of isopenicillin N synthase observed by X-ray diffraction von Baldwin, Jack E, Burzlaff, Nicolai I, Rutledge, Peter J, Clifton, Ian J, Hensgens, Charles M. H, Pickford, Michael, Adlington, Robert M, Roach, Peter L

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Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes von Roach, Peter L, Clifton, Ian J, Fülöp, Vilmos, Harlos, Karl, Barton, Geoffrey J, Hajdu, Janos, Andersson, Inger, Schofield, Christopher J, Baldwin, Jack E

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X-ray Crystal Structure of Escherichia coli Taurine/α-Ketoglutarate Dioxygenase Complexed to Ferrous Iron and Substrates von Elkins, Jonathan M, Ryle, Matthew J, Clifton, Ian J, Dunning Hotopp, Julie C, Lloyd, John S, Burzlaff, Nicolai I, Baldwin, Jack E, Hausinger, Robert P, Roach, Peter L

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Multiplexed suspension array platform for high-throughput protein assays von Birtwell, S. W., Broder, G. R., Roach, P. L., Morgan, H.

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Thiamine biosynthesis in Escherichia coli: isolation and initial characterisation of the ThiGH complex von Leonardi, Roberta, Fairhurst, Shirley A, Kriek, Marco, Lowe, David J, Roach, Peter L

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Bead-based immunoassays using a micro-chip flow cytometer von Holmes, David, She, Joseph K, Roach, Peter L, Morgan, Hywel

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Investigations into the post-translational modification and mechanism of isopenicillin N-acyl-CoA acyltransferase using electrospray mass spectrometry von APLIN, R. T, BALDWIN, J. E, ROACH, P. L, ROBINSON, C. V, SCHOFIELD, C. J

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Crystallization and preliminary X‐ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans von Roach, Peter L., Schofield, Christopher J., Baldwin, Jack E., Clifton, Ian J., Hajdu, Janos

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Mutagenesis of the proposed iron-sulfur cluster binding ligands in Escherichia coli biotin synthase von Hewitson, Kirsty S, Baldwin, Jack E, Shaw, Nicholas M, Roach, Peter L

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MioC is an FMN-binding protein that is essential for Escherichia coli biotin synthase activity in vitro von Birch, O M, Hewitson, K S, Fuhrmann, M, Burgdorf, K, Baldwin, J E, Roach, P L, Shaw, N M

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Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans von Sami, Malkit, Brown, Toby J.N, Roach, Peter L, Schofield, Christosper J, Baldwin, Jack E

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Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity von Leonardi, Roberta, Roach, Peter L

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Thiamine Biosynthesis in Escherichia coli: In vutro reconstitution of the thiazole synthase activity von Leonardi, R, Roach, P L

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An analysis of the feasibility of short read sequencing von Whiteford, Nava, Haslam, Niall, Weber, Gerald, Prügel-Bennett, Adam, Essex, Jonathan W., Roach, Peter L., Bradley, Mark, Neylon, Cameron

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Structure of a specific acyl-enzyme complex formed between β-casomorphin-7 and porcine pancreatic elastase von Wilmouth, Rupert C, Clifton, Ian J, Robinson, Carol V, Roach, Peter L, Aplin, Robin T, Westwood, Nicholas J, Hajdu, Janos, Schofield, Christopher J

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The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate von Bryant, Penny, Kriek, Marco, Wood, Robert J., Roach, Peter L.

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Structural Studies on the Reaction of Isopenicillin N Synthase with the Truncated Substrate Analogues δ-(l-α-aminoadipoyl)-l-cysteinyl-glycine and δ-(l-α-aminoadipoyl)-l-cysteinyl-... von Long, Alexandra J, Clifton, Ian J, Roach, Peter L, Baldwin, Jack E, Rutledge, Peter J, Schofield, Christopher J

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Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate von Long, Alexandra J, Clifton, Ian J, Roach, Peter L, Baldwin, Jack E, Schofield, Christopher J, Rutledge, Peter J

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