Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells von Remsing Rix, L L, Rix, U, Colinge, J, Hantschel, O, Bennett, K L, Stranzl, T, Müller, A, Baumgartner, C, Valent, P, Augustin, M, Till, J H, Superti-Furga, G

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Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site von Hadzijusufovic, E, Albrecht-Schgoer, K, Huber, K, Hoermann, G, Grebien, F, Eisenwort, G, Schgoer, W, Herndlhofer, S, Kaun, C, Theurl, M, Sperr, W R, Rix, U, Sadovnik, I, Jilma, B, Schernthaner, G H, Wojta, J, Wolf, D, Superti-Furga, G, Kirchmair, R, Valent, P

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Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth von Peter, B, Winter, G E, Blatt, K, Bennett, K L, Stefanzl, G, Rix, U, Eisenwort, G, Hadzijusufovic, E, Gridling, M, Dutreix, C, Hoermann, G, Schwaab, J, Radia, D, Roesel, J, Manley, P W, Reiter, A, Superti-Furga, G, Valent, P

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A chemical biology approach identifies AMPK as a modulator of melanoma oncogene MITF von Borgdorff, V, Rix, U, Winter, G E, Gridling, M, Müller, A C, Breitwieser, F P, Wagner, C, Colinge, J, Bennett, K L, Superti-Furga, G, Wagner, S N

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A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells von Rix, U, Remsing Rix, L L, Terker, A S, Fernbach, N V, Hantschel, O, Planyavsky, M, Breitwieser, F P, Herrmann, H, Colinge, J, Bennett, K L, Augustin, M, Till, J H, Heinrich, M C, Valent, P, Superti-Furga, G

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Immunosuppression and atypical infections in CML patients treated with dasatinib at 140 mg daily von Sillaber, C., Herrmann, H., Bennett, K., Rix, U., Baumgartner, C., Böhm, A., Herndlhofer, S., Tschachler, E., Superti-Furga, G., Jäger, U., Valent, P.

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Polypharmacology-based ceritinib repurposing using integrated functional proteomics von Kuenzi, Brent M, Remsing Rix, Lily L, Stewart, Paul A, Fang, Bin, Kinose, Fumi, Bryant, Annamarie T, Boyle, Theresa A, Koomen, John M, Haura, Eric B, Rix, Uwe

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Dissecting the landscape of CAF-mediated drug resistance mechanisms in ALK-rearranged NSCLC von Hu, Q., Rix, L.L. Remsing, Li, X., Welsh, E.A., Fang, B., Yun, S., Kroeger, J., Lawrence, H.R., Marusyk, A., Koomen, J.M., Haura, E.B., Rix, U.

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Deploying ibrutinib to lung cancer: another step in the quest towards drug repurposing von Haura, Eric B, Rix, Uwe

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B40 IGF-Binding Protein-Mediated Sensitization of EGFR-Mutant NSCLC Cells to Osimertinib by Cancer-Associated Fibroblast von Remsing Rix, L.L., Sumi, N.J., Bryant, A.T., Desai, B., Li, X., Welsh, E.A., Fang, B., Kuenzi, B.M., Antonia, S.J., Lovly, C.M., Koomen, J.M., Marusyk, A., Haura, E.B., Rix, U.

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The Dynamic Structure of Jadomycin B and the Amino Acid Incorporation Step of Its Biosynthesis von Rix, Uwe, Zheng, Jianting, Remsing Rix, Lily L, Greenwell, Lisa, Yang, Keqian, Rohr, Jürgen

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Modification of post-PKS tailoring steps through combinatorial biosynthesis von Rix, Uwe, Fischer, Carsten, Remsing, Lily L, Rohr, Jürgen

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Repurposing Ceritinib Using Systems Polypharmacology von Kuenzi, B., Remsing Rix, L., Stewart, P., Fang, B., Kinose, F., Bryant, A., Boyle, T., Koomen, J., Haura, E., Rix, U.

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Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics von Gridling, Manuela, Ficarro, Scott B, Breitwieser, Florian P, Song, Lanxi, Parapatics, Katja, Colinge, Jacques, Haura, Eric B, Marto, Jarrod A, Superti-Furga, Giulio, Bennett, Keiryn L, Rix, Uwe

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Oxidative Ring Cleavage in Jadomycin Biosynthesis: A Multistep Oxygenation Cascade in a Biosynthetic Black Box von Rix, Uwe, Wang, Chenchen, Chen, Yihua, Lipata, Fredilyn M, Remsing Rix, Lily L, Greenwell, Lisa M, Vining, Leo C, Yang, Keqian, Rohr, Jürgen

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Systems biology analysis of protein-drug interactions von Colinge, Jacques, Rix, Uwe, Bennett, Keiryn L., Superti-Furga, Giulio

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Functional Analyses of Oxygenases in Jadomycin Biosynthesis and Identification of JadH as a Bifunctional Oxygenase/Dehydrase von Chen, Yi-Hua, Wang, Chen-Chen, Greenwell, Lisa, Rix, Uwe, Hoffmeister, Dirk, Vining, Leo C., Rohr, Jürgen, Yang, Ke-Qian

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Mithramycin SK, A Novel Antitumor Drug with Improved Therapeutic Index, Mithramycin SA, and Demycarosyl-mithramycin SK:  Three New Products Generated in the Mithramycin Producer St... von REMSING, Lily L., GONZáLEZ, Ana M., NUR-E-ALAM, Mohammad, FERNáNDEZ-LOZANO, M. José, BRAñA, Alfredo F., RIX, Uwe, OLIVEIRA, Marcos A., MéNDEZ, Carmen, SALAS, José A., ROHR, Jürgen

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Identification of the Function of Gene lndM2 Encoding a Bifunctional Oxygenase-Reductase Involved in the Biosynthesis of the Antitumor Antibiotic Landomycin E by Streptomyces globi... von ZHU, Lili, OSTASH, Bohdan, RIX, Uwe, NUR-E-ALAM, Mohammad, MAYERS, Almuth, LUZHETSKYY, Andriy, MENDEZ, Carmen, SALAS, Jose A., BECHTHOLD, Andreas, FEDORENKO, Victor, ROHR, Jürgen

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Rationally Designed Glycosylated Premithramycins:  Hybrid Aromatic Polyketides Using Genes from Three Different Biosynthetic Pathways von Trefzer, Axel, Blanco, Gloria, Remsing, Lily, Künzel, Eva, Rix, Uwe, Lipata, Fredilyn, Braña, Alfredo F, Méndez, Carmen, Rohr, Jürgen, Bechthold, Andreas, Salas, José A

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