Abstract P2-11-05: Generating real-world external comparators for randomized clinical trials (RCTs) in metastatic breast cancer (mBC) using electronic health records (EHRs) von Amiri-Kordestani, Laleh, Gao, Xin, Baxi, Shrujal, Bloomquist, Erik, Bryan, Jonathan, Howie, Lynn, Keane, Catherine, Kluetz, Paul G., Osgood, Christy, Paliwal, Prashni, Rivera, Donna R., Roose, James, Schneider, Julie, Singh, Harpreet, Tang, Shenghui, Zhang, Lijun, Beaver, Julia A.

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Abstract 5248: CDK4/6 inhibition (CDK4/6i) is effective in the real-world setting for hormone receptor-positive metastatic breast cancer (HR+ MBC) with ESR1 mutations and fusions von Brett, Jamie O., Weipert, Caroline M., Ritterhouse, Lauren L., Zhang, Nicole, Yu, Junhua, Ryan, Lianne Y., Spring, Laura M., Rivera, Miguel N., Lennerz, Jochen K., Dias-Santagata, Dora, Ellisen, Leif W., Bardia, Aditya, Wander, Seth A.

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Mutations of the catalytic domain of PI3 kinase and correlation with clinical outcome in trastuzumab-treated metastatic breast cancer (MBC) von Cook, J. W., Paxinos, E., Goodman, L. J., Ali, S. M., Leitzel, K., Koestler, W., Rivera, A., Weidler, J. M., Huang, W., Sperinde, J., Williams, S. J., Bates, M., Lipton, A.

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Weekly versus 3-weekly docetaxel (D2) plus doxorubicin (D4) for first-line treatment of metastatic breast cancer (MBC) von Stemmler, H., Harbeck, N., Groell der Rivera, I., Vehling-Kaiser, U., Rauthe, G., Abenhardt, W., Sommer, H., Meerpohl, H., Kiechle, M., Heinemann, V.

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Progression-free survival (PFS) in patient subgroups in RIBBON-2, a phase III trial of chemotherapy (chemo) plus or minus bevacizumab (BV) for second-line treatment of HER2-negative, locally recurrent or metastatic breast cancer (MBC) von Brufsky, A., Rivera, R. R., Hurvitz, S. A., Bondarenko, I. N., Smirnov, V., Valero, V., Rugo, H. S., Swamy, R., Mu, H., Perez, E. A.

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Phase I trial of escalating doses of weekly everolimus (RAD001) in combination with docetaxel for the treatment of metastatic breast cancer (MBC) von Moulder, S. L., Rivera, E., Ensor, J., Gonzalez-Angulo, A., Christofanilli, M., Booser, D., Giordano, S., Brewster, A., Hortobagyi, G., Tran, H.

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PCN63 DIFFERENT TREATMENT PATTERNS COSTS IN METASTATIC BREAST CANCER (MBC) EXPOSED TO ANTHRACYCLINHES AND TAXANES (AT) IN 3 DIFFERENT MEXICAN PUBLIC HOSPITALS von Juarez-Garcia, A, Hernandez-Rivera, G, Gómez-Roel, X, Uc-Coyoc, R, Rangel, S, Vargas-Valencia, JJ, Martínez-Fonseca, J, Donato, BM, Litalien, G

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