Optimization of 3,5-Dimethylisoxazole Derivatives as Potent Bromodomain Ligands von Hewings, David S, Fedorov, Oleg, Filippakopoulos, Panagis, Martin, Sarah, Picaud, Sarah, Tumber, Anthony, Wells, Christopher, Olcina, Monica M, Freeman, Katherine, Gill, Andrew, Ritchie, Alison J, Sheppard, David W, Russell, Angela J, Hammond, Ester M, Knapp, Stefan, Brennan, Paul E, Conway, Stuart J

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Enabling better end of life communication in residential aged care von Clayton, Josephine M, Ritchie, Alison J, Butow, Phyllis N

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A New Apo-Caspase-6 Crystal Form Reveals the Active Conformation of the Apoenzyme von Müller, Ilka, Lamers, Marieke B.A.C., Ritchie, Alison J., Park, Hyunsun, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Maillard, Michel, Kiselyov, Alex

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Structure of human caspase-6 in complex with Z-VAD-FMK: New peptide binding mode observed for the non-canonical caspase conformation von Müller, Ilka, Lamers, Marieke B.A.C., Ritchie, Alison J., Dominguez, Celia, Munoz-Sanjuan, Ignacio, Kiselyov, Alex

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Rational Design of Peptide-Based HIV Proteinase Inhibitors von Roberts, Noel A., Martin, Joseph A., Kinchington, Derek, Broadhurst, Anne V., Craig, J. Charles, Duncan, Ian B., Galpin, Sarah A., Handa, Balraj K., Kay, John, Kröhn, Antonin, Lambert, Robert W., Merrett, John H., Mills, John S., Kevin E. B. Parkes, Redshaw, Sally, Ritchie, Alison J., Taylor, Debra L., Thomas, Gareth J., Machin, Peter J.

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Herpes simplex virus type 1 gene UL13 encodes a phosphoprotein that is a component of the virion von Overton, Hilary A., McMillan, David J., Klavinskis, Linda S., Hope, Louise, Ritchie, Alison J., Wong-Kai-In, Philippe

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Hydrolysis of synthetic chromogenic substrates by HIV-1 and HIV-2 proteinases von Phylip, Lowri H., Richards, Anthony D., Kay, John, Konvalinka, Jan, Strop, Peter, Blana, Ivo, Velek, Jiri, Kostka, Vladimir, Ritchie, Alison J., Broadhurst, Anne V., Farmerie, William G., Scarborough, Paula E., Dunn, Ben M.

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Inhibition of the aspartic proteinase from HIV-2 von Richards, Anthony D., Broadhurst, Anne V., Ritchie, Alison J., Dunn, Ben M., Kay, John

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Assay of HIV-1 proteinase: A colorimetric method using small peptide substrates von Broadhurst, Anne V., Roberts, Noel A., Ritchie, Alison J., Handa, Balraj K., Kay, Corinne

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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial von Folegatti, Pedro M, Bibi, Sagida, Chappell, Harry, Fedosyuk, Sofiya, Gbesemete, Diane, Kelly, Elizabeth J, Makinson, Rebecca, Rawlinson, Thomas, Ross-Russell, Amy L, Saich, Stephen, Smith, Catherine C, Tarrant, Richard, Thomas, Kelly M, Warren, Sarah C, Lambe, Teresa, Adams, Kelly, Ali, Aabidah, Allen, Lauren, Baker, Natalie, Barrett, Kelly, Bellamy, Duncan, Berg, Adam, Beveridge, Amy, Bewley, Kevin, Bijker, Else M., Boland, Elena, Bormans, Daan, Bower, Thomas, Boyd, Amy, Brenner, Tanja, Buttigieg, Karen R., Cao, Michelangelo, Chapman, David, Chelysheva, Irina, Cifuentes, Liliana, Collins, Sarah, Conlon, Christopher P., Davis, Judith, Dong, Tao, Drake, Jonathan, Fisher, Richard, Garlant, Harriet, Gavrila, Madita, Gibbons, Felicity, Gill, Hardeep, Hart, Thomas C., Hartnell, Birgit, Haskell, Louise, Hawkins, Sophia, Hermosin Herrera, Macarena, Hill, David, Hill, Jennifer, Howes, Jessica, Jackson, Susan, Joshi, Amar, Kelly, Dearbhla M., King, Lloyd D.W., Knott, Daniel, Lee, Kim Y.N., Leung, Stephanie, Liu, Shuchang, Loew, Lisa, Madhavan, Meera, Marius, Phedra, Marshall, Julia L., Martin, Jane, Moore, Maria, Morris, Susan J., O'Reilly, Peter John, Owino, Nelly, Patel, Bhumika, Patrick-Smith, Maia, Perring, James, Phillips, Daniel J., Poulton, Ian, Presland, Laura, Pulido, David, Rajapaska, Durga, Ramos Lopez, Fernando, Rollier, Christine S., Romani, Rossana, Sedik, Cynthia, Seddiqi, Samiullah, Segireddy, Rameswara R., Sharpe, Hannah R., Silva-Reyes, Laura, Smith, David J., Smith, Daniel C., Smith, Nicholas, Stockley, David, Summerton, Eloise, Szigeti, Anna, Taylor, Ursula, Tonks, Susan, Tree, Julian A., Truby, Adam, Varughese, Rachel, Woodyer, Mark, Worth, Andrew T., Yao, Xin Li

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Epigenetic prediction of complex traits and death von McCartney, Daniel L, Hillary, Robert F, Stevenson, Anna J, Ritchie, Stuart J, Walker, Rosie M, Zhang, Qian, Morris, Stewart W, Bermingham, Mairead L, Campbell, Archie, Murray, Alison D, Whalley, Heather C, Gale, Catharine R, Porteous, David J, Haley, Chris S, McRae, Allan F, Wray, Naomi R, Visscher, Peter M, McIntosh, Andrew M, Evans, Kathryn L, Deary, Ian J, Marioni, Riccardo E

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GWAS on family history of Alzheimer’s disease von Marioni, Riccardo E., Harris, Sarah E., Zhang, Qian, McRae, Allan F., Hagenaars, Saskia P., Hill, W. David, Davies, Gail, Ritchie, Craig W., Gale, Catharine R., Starr, John M., Goate, Alison M., Porteous, David J., Yang, Jian, Evans, Kathryn L., Deary, Ian J., Wray, Naomi R., Visscher, Peter M.

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Late Ebola virus relapse causing meningoencephalitis: a case report von Jacobs, Michael, Dr, Rodger, Alison, FRCP, Bell, David J, MRCP, Bhagani, Sanjay, FRCP, Cropley, Ian, FRCP, Filipe, Ana, PhD, Gifford, Robert J, PhD, Hopkins, Susan, FRCP, Hughes, Joseph, PhD, Jabeen, Farrah, FRCR, Johannessen, Ingolfur, FRCPath, Karageorgopoulos, Drosos, MRCP, Lackenby, Angie, PhD, Lester, Rebecca, MRCP, Liu, Rebecca S N, FRCP, MacConnachie, Alisdair, MRCP, Mahungu, Tabitha, MRCP, Martin, Daniel, FRCA, Marshall, Neal, MRPharmS, Mepham, Stephen, FRCPath, Orton, Richard, PhD, Palmarini, Massimo, Prof, Patel, Monika, MSc, Perry, Colin, FRCP, Peters, S Erica, MRCP, Porter, Duncan, MD, Ritchie, David, FRCR, Ritchie, Neil D, MRCP, Seaton, R Andrew, FRCP, Sreenu, Vattipally B, PhD, Templeton, Kate, FRCPath, Warren, Simon, FRCPath, Wilkie, Gavin S, PhD, Zambon, Maria, FRCPath, Gopal, Robin, PhD, Thomson, Emma C, FRCP

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Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial von Parker, Christopher C, James, Nicholas D, Brawley, Christopher D, Clarke, Noel W, Hoyle, Alex P, Ali, Adnan, Ritchie, Alastair W S, Attard, Gerhardt, Chowdhury, Simon, Cross, William, Dearnaley, David P, Gillessen, Silke, Gilson, Clare, Jones, Robert J, Langley, Ruth E, Malik, Zafar I, Mason, Malcolm D, Matheson, David, Millman, Robin, Russell, J Martin, Thalmann, George N, Amos, Claire L, Alonzi, Roberto, Bahl, Amit, Birtle, Alison, Din, Omar, Douis, Hassan, Eswar, Chinnamani, Gale, Joanna, Gannon, Melissa R, Jonnada, Sai, Khaksar, Sara, Lester, Jason F, O'Sullivan, Joe M, Parikh, Omi A, Pedley, Ian D, Pudney, Delia M, Sheehan, Denise J, Srihari, Narayanan Nair, Tran, Anna T H, Parmar, Mahesh K B, Sydes, Matthew R

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Safety profile of autologous macrophage therapy for liver cirrhosis von Moroni, Francesca, Dwyer, Benjamin J., Graham, Catriona, Pass, Chloe, Bailey, Laura, Ritchie, Lisa, Mitchell, Donna, Glover, Alison, Laurie, Audrey, Doig, Stuart, Hargreaves, Emily, Fraser, Alasdair R., Turner, Marc L., Campbell, John D. M., McGowan, Neil W. A., Barry, Jacqueline, Moore, Joanna K., Hayes, Peter C., Leeming, Diana J., Nielsen, Mette J., Musa, Kishwar, Fallowfield, Jonathan A., Forbes, Stuart J.

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A global review of seed enhancement technology use to inform improved applications in restoration von Brown, Vanessa S., Erickson, Todd E., Merritt, David J., Madsen, Matthew D., Hobbs, Richard J., Ritchie, Alison L.

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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four random... von Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Feng, Shuo, Marshall, Richard P, Milan, Eveline P, Pollock, Katrina M, Ramasamy, Maheshi N, Robinson, Hannah, Andrade, Claudia Sala, Barker, Debbie, Bates, Louise, Batten, Alexander, Berzenyi, Daniella, Bird, Adam, Blundell, Susannah R., Budd, William, Cabrera Puig, Ingrid, Calvert, Anna, Carvalho, Yasmin de M., Castro, Thais R.Y., Chiplin, Emily, Cifuentes, Liliana, Danos, Zsofia, Dantas, Maria T.D.C., Davies, Sophie, Desai, Amisha, Drake-Brockman, Rachael, Edwards, Mandy, Edwards, Nick J., El Muhanna, Omar M., Ellison-Handley, Branwen, Fedosyuk, Sofiya, Fisher, Richard, Fofie, Hazel, Franco, Marilia M., Fuskova, Michelle, Godwin, Kerry, Gokani, Karishma, Gonçalves, Maria Luisa Freire, Goodall, Jack, Harris-Wright, Tara A., Howell, Nicola, Humphreys, Jonathan, Iyer, Vidyashankara, Jackson, Susan, Jaumdally, Shameem, Jorge, Marianna Rocha, Kellett Wright, Johanna, Kelly, Elizabeth J., Kelly, Dearbhla M., Kidd, Sarah, Larwood, Jessica P.J., Lees, Emily A., Lelliott, Alice, Leung, Stephanie, Manning, Nicola, Mazur, Olga, McGlashan, Joanna, Megson, Clare, Mesquita, Ana Carolina F., Mitton, Celia, Morrison, Hazel, Morselli, Franca, Oliveira, Catarina, Oosthuizen, Angela, Owen, David R.J., Parracho, Helena M. R.T., Perez, Ana Luiza, Perinpanathan, Tanaraj, Perumal, Rubeshan, Plank, Mary, Proud, Pamela C., Rajeswaran, Thurkka, Rees, Byron, Rhead, Sarah, Richards, Alexander, Roberts, Hannah, Robinson, Ryan E., Rudiansyah, Indra, Saunders, Jack E., Screaton, Gavin R., Sorley, Kim, Spencer, Alexandra J., Spoors, Louise, Stein, Ricardo, Strickland, Louise H., Sturdy, Ann, Sutton, Natalina, Taoushanis, Carol, Thomas, Merin, Tinoco, Lygia Accioly, Tomic, Adriana, Truby, Adam, Underwood, Benjamin R., Vichos, Iason, Watkins, Bridget, Wellbelove, Zoe, White, Caroline, Willingham, Silvia

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Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936 von Dickie, David Alexander, PhD, Ritchie, Stuart J., PhD, Cox, Simon R., PhD, Sakka, Eleni, MSc, Royle, Natalie A., PhD, Aribisala, Benjamin S., PhD, Hernández, Maria del C. Valdés, PhD, Muñoz Maniega, Susana, PhD, Pattie, Alison, BSc, Corley, Janie, MA, Starr, John M., PhD/MD, Bastin, Mark E., PhD, Deary, Ian J., PhD/MD, Wardlaw, Joanna M., PhD/MD

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An epigenetic predictor of death captures multi-modal measures of brain health von Hillary, Robert F., Stevenson, Anna J., Cox, Simon R., McCartney, Daniel L., Harris, Sarah E., Seeboth, Anne, Higham, Jon, Sproul, Duncan, Taylor, Adele M., Redmond, Paul, Corley, Janie, Pattie, Alison, Hernández, Maria del. C. Valdés, Muñoz-Maniega, Susana, Bastin, Mark E., Wardlaw, Joanna M., Horvath, Steve, Ritchie, Craig W., Spires-Jones, Tara L., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J., Marioni, Riccardo E.

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Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial von James, Nicholas D, Prof, Sydes, Matthew R, CSci, Mason, Malcolm D, Prof, Clarke, Noel W, Prof, Anderson, John, MD, Dearnaley, David P, Prof, Dwyer, John, FRIC, Jovic, Gordana, PhD, Ritchie, Alastair WS, FRCSEd, Russell, J Martin, FRCR, Sanders, Karen, BSc, Thalmann, George N, Prof, Bertelli, Gianfilippo, MD, Birtle, Alison J, FRCR, O'Sullivan, Joe M, Prof, Protheroe, Andrew, PhD, Sheehan, Denise, FRCR, Srihari, Narayanan, FRCR, Parmar, Mahesh KB, Prof

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