Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma von Coy, Shannon, Wang, Shu, Stopka, Sylwia A., Lin, Jia-Ren, Yapp, Clarence, Ritch, Cecily C., Salhi, Lisa, Baker, Gregory J., Rashid, Rumana, Baquer, Gerard, Regan, Michael, Khadka, Prasidda, Cole, Kristina A., Hwang, Jaeho, Wen, Patrick Y., Bandopadhayay, Pratiti, Santi, Mariarita, De Raedt, Thomas, Ligon, Keith L., Agar, Nathalie Y. R., Sorger, Peter K., Touat, Mehdi, Santagata, Sandro

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Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors von Burger, Megan L., Cruz, Amanda M., Crossland, Grace E., Gaglia, Giorgio, Ritch, Cecily C., Blatt, Sarah E., Bhutkar, Arjun, Canner, David, Kienka, Tamina, Tavana, Sara Z., Barandiaran, Alexia L., Garmilla, Andrea, Schenkel, Jason M., Hillman, Michelle, de los Rios Kobara, Izumi, Li, Amy, Jaeger, Alex M., Hwang, William L., Westcott, Peter M.K., Manos, Michael P., Holovatska, Marta M., Hodi, F. Stephen, Regev, Aviv, Santagata, Sandro, Jacks, Tyler

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Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma von Gaglia, Giorgio, Burger, Megan L., Ritch, Cecily C., Rammos, Danae, Dai, Yang, Crossland, Grace E., Tavana, Sara Z., Warchol, Simon, Jaeger, Alex M., Naranjo, Santiago, Coy, Shannon, Nirmal, Ajit J., Krueger, Robert, Lin, Jia-Ren, Pfister, Hanspeter, Sorger, Peter K., Jacks, Tyler, Santagata, Sandro

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Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity von Zhang, Xue, Pant, Shishir M., Ritch, Cecily C., Tang, Hsin-Yao, Shao, Hongguang, Dweep, Harsh, Gong, Yao-Yu, Brooks, Rebekah, Brafford, Patricia, Wolpaw, Adam J., Lee, Yool, Weeraratna, Ashani, Sehgal, Amita, Herlyn, Meenhard, Kossenkov, Andrew, Speicher, David, Sorger, Peter K., Santagata, Sandro, Dang, Chi V.

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Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data von Warchol, Simon, Krueger, Robert, Nirmal, Ajit Johnson, Gaglia, Giorgio, Jessup, Jared, Ritch, Cecily C., Hoffer, John, Muhlich, Jeremy, Burger, Megan L., Jacks, Tyler, Santagata, Sandro, Sorger, Peter K., Pfister, Hanspeter

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Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data von Jessup, Jared, Krueger, Robert, Warchol, Simon, Hoffer, John, Muhlich, Jeremy, Ritch, Cecily C., Gaglia, Giorgio, Coy, Shannon, Chen, Yu-An, Lin, Jia-Ren, Santagata, Sandro, Sorger, Peter K., Pfister, Hanspeter

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Abstract P010: Antigen dominance hierarchies shape CD8 T cell phenotypes and immunotherapy response in tumors von Burger, Megan L., Cruz, Amanda M., Crossland, Grace E., Gaglia, Giorgio, Ritch, Cecily C., Blatt, Sarah E., Bhutkar, Arjun, Tavana, Sara Z., Santagata, Sandro, Jacks, Tyler

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Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data von Jessup, Jared, Krueger, Robert, Warchol, Simon, Hoffer, John, Muhlich, Jeremy, Ritch, Cecily C, Gaglia, Giorgio, Coy, Shannon, Yu-An, Chen, Jia-Ren, Lin, Santagata, Sandro, Sorger, Peter K, Pfister, Hanspeter

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labsyspharm/Melanoma_BMAL1_Plasticity: v1.0.0 von Zhang, Xue, Pant, Shishir, Ritch, Cecily, Tang, Hsin-Yao, Shao, Hongguang, Dweep, Harsh, Gong, Yao-Yu, Brooks, Rebekah, Brattford, Patricia, Wolpaw, Adam, Lee, Yool, Weeraratna, Ashani, Sehgal, Amita, Herlyn, Meenhard, Kossenkov, Andrew, Speicher, David W., Sorger, Peter, Santagata, Sandro, Dang, Chi V.

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Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer von Herberts, Cameron, Annala, Matti, Sipola, Joonatan, Ng, Sarah W. S., Chen, Xinyi E., Nurminen, Anssi, Korhonen, Olga V., Munzur, Aslı D., Beja, Kevin, Schönlau, Elena, Bernales, Cecily Q., Ritch, Elie, Bacon, Jack V. W., Lack, Nathan A., Nykter, Matti, Aggarwal, Rahul, Small, Eric J., Gleave, Martin E., Quigley, David A., Feng, Felix Y., Chi, Kim N., Wyatt, Alexander W.

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A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomes von Ritch, Elie J., Herberts, Cameron, Warner, Evan W., Ng, Sarah W. S., Kwan, Edmond M., Bacon, Jack V. W., Bernales, Cecily Q., Schönlau, Elena, Fonseca, Nicolette M., Giri, Veda N., Maurice-Dror, Corinne, Vandekerkhove, Gillian, Jones, Steven J. M., Chi, Kim N., Wyatt, Alexander W.

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Multiregion sampling of de novo metastatic prostate cancer reveals complex polyclonality and augments clinical genotyping von Warner, Evan W, Van der Eecken, Kim, Murtha, Andrew J, Kwan, Edmond M, Herberts, Cameron, Sipola, Joonatan, Ng, Sarah W S, Chen, Xinyi E, Fonseca, Nicolette M, Ritch, Elie, Schönlau, Elena, Bernales, Cecily Q, Donnellan, Gráinne, Munzur, Aslı D, Parekh, Karan, Beja, Kevin, Wong, Amanda, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, De Laere, Bram, Annala, Matti, Vandekerkhove, Gillian, Ost, Piet, Wyatt, Alexander W

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Genomic Features of Lung-Recurrent Hormone-Senstive Prostate Cancer von Fonseca, Nicolette M, Van der Eecken, Kim, Herberts, Cameron, Verbeke, Sofie, Ng, Sarah W.S, Lumen, Nicolaas, Ritch, Elie, Murtha, Andrew J, Bernales, Cecily Q, Schonlau, Elena, Moris, Lisa, Van Dorpe, Jo, Annala, Matti, Wyatt, Alexander W, Ost, Piet

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Abstract IA006: Overcoming complex polyclonality for accurate clinical genotyping in metastatic prostate cancer von Wyatt, Alexander W., Murtha, Andrew J., Warner, Evan, Van der Eecken, Kim, Kwan, Edmond M., Herberts, Cameron, Sipola, Joonatan, Ng, Sarah W.S., Chen, Xinyi E., Fonseca, Nicolette M., Ritch, Elie, Schönlau, Elena, Bernales, Cecily Q., Donnellan, Gráinne, Beja, Kevin, Wong, Amanda, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, De Laere, Bram, Annala, Matti, Vandekerkhove, Gillian, Ost, Piet

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Abstract 3625: Clonal architecture and evolution of treatment-resistant prostate cancer via deep whole-genome ctDNA sequencing von Herberts, Cameron, Annala, Matti, Sipola, Joonatan, Ng, Sarah W., Chen, Xinyi E., Nurminen, Anssi, Korhonen, Olga, Munzur, Aslı D., Beja, Kevin, Schönlau, Elena, Bernales, Cecily Q., Ritch, Elie, Bacon, Jack V., Lack, Nathan A., Nykter, Matti, Aggarwal, Rahul, Small, Eric J., Gleave, Martin E., Quigley, David A., Feng, Felix Y., Chi, Kim N., Wyatt, Alexander W.

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Abstract 41: Multi-focal genomic dissection of synchronous primary and metastatic tissue from de novo metastatic prostate cancer von Warner, Evan, Van der Eecken, Kim, Murtha, Andrew J., Kwan, Edmond M., Ng, Sarah W., Chen, Xinyi E., Bernales, Cecily Q., Donnellan, Grainne, Schonlau, Elena, Verbeke, Sofie, Lumen, Nicolaas, Van Dorpe, Jo, Vandekerkhove, Gillian, Ritch, Elie, Annala, Matti, De Laere, Bram, Ost, Piet, Wyatt, Alexander W.

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The African Descent and Glaucoma Evaluation Study (ADAGES): Design and Baseline Data von Sample, Pamela A, Girkin, Christopher A, Zangwill, Linda M, Jain, Sonia, Racette, Lyne, Becerra, Lida M, Weinreb, Robert N, Medeiros, Felipe A, Wilson, M. Roy, De León-Ortega, Julio, Tello, Celso, Bowd, Christopher, Liebmann, Jeffrey M

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Clinical and genomic indolence in lung-recurrent metastatic hormone-sensitive prostate cancer von Fonseca, Nicolette, Van der Eecken, Kim, Herberts, Cameron, Verbeke, Sofie, Ng, Sarah, Lumen, Nicolaas, Ritch, Elie, Murtha, Andrew, Bernales, Cecily, Schönlau, Elena, Moris, Lisa, Van Dorpe, Jo, Annala, Matti, Wyatt, Alexander, Ost, Piet

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Genomic features of lung-recurrent hormone sensitive prostate cancer von Van der Eecken, Kim, Fonseca, Nicolette, Herberts, Cameron, Verbeke, Sofie, Ng, Sarah, Lumen, Nicolaas, Ritch, Elie, Murtha, Andrew, Bernales, Cecily, Schönlau, Elena, Moris, Lisa, Van Dorpe, Jo, Annala, Matti, Wyatt, Alexander, Ost, Piet

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