General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis von Baxter, Nicholas J., Laws, Andrew P., Rigoreau, Laurent J. H., Page, Michael I.

Volltext

Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2 von Caldwell, John J, Welsh, Emma J, Matijssen, Cornelis, Anderson, Victoria E, Antoni, Laurent, Boxall, Kathy, Urban, Frederique, Hayes, Angela, Raynaud, Florence I, Rigoreau, Laurent J. M, Raynham, Tony, Aherne, G. Wynne, Pearl, Laurence H, Oliver, Antony W, Garrett, Michelle D, Collins, Ian

Volltext

Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4 von Myers, Stephanie M., Miller, Duncan C., Molyneux, Lauren, Arasta, Mercedes, Bawn, Ruth H., Blackburn, Timothy J., Cook, Simon J., Edwards, Noel, Endicott, Jane A., Golding, Bernard T., Griffin, Roger J., Hammonds, Tim, Hardcastle, Ian R., Harnor, Suzannah J., Heptinstall, Amy B., Lochhead, Pamela A., Martin, Mathew P., Martin, Nick C., Newell, David R., Owen, Paul J., Pang, Leon C., Reuillon, Tristan, Rigoreau, Laurent J.M., Thomas, Huw D., Tucker, Julie A., Wang, Lan-Zhen, Wong, Ai-Ching, Noble, Martin E.M., Wedge, Stephen R., Cano, Celine

Volltext

High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors von Myers, Stephanie M, Bawn, Ruth H, Bisset, Louise C, Blackburn, Timothy J, Cottyn, Betty, Molyneux, Lauren, Wong, Ai-Ching, Cano, Celine, Clegg, William, Harrington, Ross. W, Leung, Hing, Rigoreau, Laurent, Vidot, Sandrine, Golding, Bernard T, Griffin, Roger J, Hammonds, Tim, Newell, David R, Hardcastle, Ian R

Volltext

Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4 von Tucker, Julie Ann, Myers, Stephanie M, Miller, Duncan C, Molyneux, Lauren, Arasta, Mercedes, Bawn, Ruth H, Blackburn, Timothy J, Cook, Simon J, Edwards, Noel, Endicott, Jane A, Golding, Bernard T, Griffin, Roger J, Hammonds, Tim, Hardcastle, Ian R, Harnor, Suzannah J, Heptinstall, Amy B, Lochhead, Pamela A, Martin, Mathew P, Martin, Nick C, Newell, David R, Owen, Paul J, Pang, Leon C, Reuillon, Tristan, Rigoreau, Laurent J.M, Thomas, Huw D, Wang, Lan-Zhen, Wong, Ai-Ching, Noble, Martin E.M, Wedge, Stephen R, Cano, Celine

Volltext bestellen