PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer von Spalinger, Marianne R., Manzini, Roberto, Hering, Larissa, Riggs, Julianne B., Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Fettelschoss, Antonia, Olomski, Florian, Kündig, Thomas M., Fried, Michael, McCole, Declan F., Rogler, Gerhard, Scharl, Michael

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Optimized Detection of Acute MHV68 Infection With a Reporter System Identifies Large Peritoneal Macrophages as a Dominant Target of Primary Infection von Riggs, Julianne B, Medina, Eva M, Perrenoud, Loni J, Bonilla, Diana L, Clambey, Eric T, van Dyk, Linda F, Berg, Leslie J

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Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup von Weckel, Antonin, Dhariwala, Miqdad O., Ly, Kevin, Tran, Victoria M., Ojewumi, Oluwasunmisola T., Riggs, Julianne B., Gonzalez, Jeanmarie R., Dwyer, Laura R., Okoro, Joy N., Leech, John M., Bacino, Margot S., Cho, Grace D., Merana, Geil, Anandasabapathy, Niroshana, Kumamoto, Yosuke, Scharschmidt, Tiffany C.

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Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N2 in Dendritic Cells to Protect from Elevated Colitis von Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Niechcial, Anna, Riggs, Julianne B., Wawrzyniak, Marcin, Atrott, Kirstin, van de Sande, Marnix, Lang, Silvia, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R.

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Loss of PTPN2 in Dendritic Cells Affects Expression of Pro-Inflammatory Cytokines but has no Major Role in the Intestine von Hering, Larissa, Riggs, Julianne B, Lang, Silvia, Atrott, Kirstin, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael M, Spalinger, Marianne

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PTPN2 Controls Intestinal Inflammation and Promotes Colitis-Associated Tumour Formation via Control of Inflammasome Activation and IL-1α Release von Spalinger, Marianne, Hering, Larissa, Manzini, Roberto, Riggs, Julianne B, Gottier, Claudia, Atrott, Kirstin, Fettelschoss, Antonia, Kündig, Thomas M, Fried, Michael, Rogler, Gerhard, Scharl, Michael M

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Macrophages Compensate for Loss of Protein Tyrosine Phosphatase N 2 in Dendritic Cells to Protect from Elevated Colitis von Hering, Larissa, Katkeviciute, Egle, Schwarzfischer, Marlene, Niechcial, Anna, Riggs, Julianne B, Wawrzyniak, Marcin, Atrott, Kirstin, van de Sande, Marnix, Lang, Silvia, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael, Spalinger, Marianne R

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Mo1706 - Loss of PTPN2 in Dendritic Cells Affects Expression of Pro-Inflammatory Cytokines but has no Major Role in the Intestine von Hering, Larissa, Riggs, Julianne B., Lang, Silvia, Atrott, Kirstin, Becher, Burkhard, Rogler, Gerhard, Scharl, Michael M., Spalinger, Marianne

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370 - PTPN2 Controls Intestinal Inflammation and Promotes Colitis-Associated Tumour Formation via Control of Inflammasome Activation and IL-1α Release von Spalinger, Marianne, Hering, Larissa, Manzini, Roberto, Riggs, Julianne B., Gottier, Claudia, Atrott, Kirstin, Fettelschoss, Antonia, Kündig, Thomas M., Fried, Michael, Rogler, Gerhard, Scharl, Michael M.

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PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer von Spalinger, Marianne R, Manzini, Roberto, Hering, Larissa, Riggs, Julianne B, Gottier, Claudia, Lang, Silvia, Atrott, Kirstin, Fettelschoss, Antonia, Olomski, Florian, Kündig, Thomas M, Fried, Michael, McCole, Declan F, Rogler, Gerhard, Scharl, Michael

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Evaluating the Clinical Validity of Gene-Disease Associations: An Evidence-Based Framework Developed by the Clinical Genome Resource von Strande, Natasha T., Riggs, Erin Rooney, Buchanan, Adam H., Ceyhan-Birsoy, Ozge, DiStefano, Marina, Dwight, Selina S., Goldstein, Jenny, Ghosh, Rajarshi, Seifert, Bryce A., Sneddon, Tam P., Wright, Matt W., Milko, Laura V., Cherry, J. Michael, Giovanni, Monica A., Murray, Michael F., O’Daniel, Julianne M., Ramos, Erin M., Santani, Avni B., Scott, Alan F., Plon, Sharon E., Rehm, Heidi L., Martin, Christa L., Berg, Jonathan S.

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ClinGen Variant Curation Interface: a variant classification platform for the application of evidence criteria from ACMG/AMP guidelines von Preston, Christine G, Wright, Matt W, Madhavrao, Rao, Harrison, Steven M, Goldstein, Jennifer L, Luo, Xi, Wand, Hannah, Wulf, Bryan, Cheung, Gloria, Mandell, Mark E, Tong, Howard, Cheng, Shaung, Iacocca, Michael A, Pineda, Arturo Lopez, Popejoy, Alice B, Dalton, Karen, Zhen, Jimmy, Dwight, Selina S, Babb, Lawrence, DiStefano, Marina, O'Daniel, Julianne M, Lee, Kristy, Riggs, Erin R, Zastrow, Diane B, Mester, Jessica L, Ritter, Deborah I, Patel, Ronak Y, Subramanian, Sai Lakshmi, Milosavljevic, Aleksander, Berg, Jonathan S, Rehm, Heidi L, Plon, Sharon E, Cherry, J Michael, Bustamante, Carlos D, Costa, Helio A

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STRONG STAR and the Consortium to Alleviate PTSD: Shaping the future of combat PTSD and related conditions in military and veteran populations von Peterson, Alan L., Young-McCaughan, Stacey, Roache, John D., Mintz, Jim, Litz, Brett T., Williamson, Douglas E., Resick, Patricia A., Foa, Edna B., McGeary, Donald D., Dondanville, Katherine A., Taylor, Daniel J., Wachen, Jennifer Schuster, Fox, Peter T., Bryan, Craig J., McLean, Carmen P., Pruiksma, Kristi E., Yarvis, Jeffrey S., Niles, Barbara L., Abdallah, Chadi G., Averill, Lynnette A., Back, Sudie E., Baker, Monty T., Blount, Tabatha H., Borah, Adam M., Borah, Elisa V., Brock, Matthew S., Brown, Lily A., Burg, Matthew M., Cigrang, Jeffrey A., DeBeer, Bryann B., DeVoe, Ellen R., Fina, Brooke A., Flanagan, Julianne C., Fredman, Steffany J., Gardner, Cubby L., Gatchel, Robert R., Goodie, Jeffrey L., Gueorguieva, Ralitza, Higgs, Jay B., Jacoby, Vanessa M., Kelly, Kevin M., Krystal, John H., Lapiz-Bluhm, M. Danet, López-Roca, Argelio L., Marx, Brian P., Maurer, Douglas M., McDevitt-Murphy, Meghan E., McGeary, Cindy A., Meyer, Eric C., Miles, Shannon R., Monson, Candice M., Morilak, David A., Moring, John C., Mysliwiec, Vincent, Nicholson, Karin L., Rauch, Sheila A.M., Riggs, David S., Rosen, Craig S., Rudd, M. David, Schobitz, Richard P., Schrader, Christian C., Shinn, Antoinette M., Shiroma, Paulo R., Sloan, Denise M., Stern, Stephen L., Strong, Randy, Vannoy, Steven D., Young, Keith A., Keane, Terence M.

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