Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death von Jo, Hakryul, Mondal, Subhanjan, Tan, Dewar, Nagata, Eiichiro, Takizawa, Shunya, Sharma, Alok K, Hou, Qingming, Shanmugasundaram, Kumaran, Prasad, Amit, Tung, Joe K, Tejeda, Alexander O, Man, Hengye, Rigby, Alan C, Luo, Hongbo R

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Pilot Study of Extracorporeal Removal of Soluble Fms-Like Tyrosine Kinase 1 in Preeclampsia von THADHANI, Ravi, KISNER, Tuelay, HEMPHILL, Linda, RIGBY, Alan C, KHEDKAR, Santosh, LINDNER, Tom H, MALLMANN, Peter, STEPAN, Holger, ANANTH KARUMANCHI, S, BENZING, Thomas, HAGMANN, Henning, BOSSUNG, Verena, NOACK, Stefanie, SCHAARSCHMIDT, Wiebke, JANK, Alexander, KRIBS, Angela, COMELY, Oliver A, KREYSSIG, Claudia

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RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription von Gerald, Damien, Adini, Irit, Shechter, Sharon, Perruzzi, Carole, Varnau, Joseph, Hopkins, Benjamin, Kazerounian, Shiva, Kurschat, Peter, Blachon, Stephanie, Khedkar, Santosh, Bagchi, Mandrita, Sherris, David, Prendergast, George C., Klagsbrun, Michael, Stuhlmann, Heidi, Rigby, Alan C., Nagy, Janice A., Benjamin, Laura E.

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Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders von Bezzerides, Vassilios J., Zhang, Aifeng, Xiao, Ling, Simonson, Bridget, Khedkar, Santosh A., Baba, Shiro, Ottaviano, Filomena, Lynch, Stacey, Hessler, Katherine, Rigby, Alan C., Milan, David, Das, Saumya, Rosenzweig, Anthony

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Shikonin, a natural product from the root of Lithospermum erythrorhizon, is a cytotoxic DNA-binding agent von Chen, Changmin, Shanmugasundaram, Kumaran, Rigby, Alan C., Kung, Andrew L.

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Optimization of a Novel Mandelamide-Derived Pyrrolopyrimidine Series of PERK Inhibitors von Stokes, Michael E, Surman, Matthew D, Calvo, Veronica, Surguladze, David, Li, An-Hu, Gasparek, Jennifer, Betzenhauser, Matthew, Zhu, Guangyu, Du, Hongwen, Rigby, Alan C, Mulvihill, Mark J

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Familial Alzheimer's disease mutations alter the stability of the amyloid β-protein monomer folding nucleus von Grant, Marianne A, Lazo, Noel D, Lomakin, Aleksey, Condron, Margaret M, Arai, Hiromi, Yamin, Ghiam, Rigby, Alan C, Teplow, David B

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Identification of Novel Non-secosteroidal Vitamin D Receptor Agonists with Potent Cardioprotective Effects and devoid of Hypercalcemia von Khedkar, Santosh A., Samad, Mohammed A., Choudhury, Sangita, Lee, Ji Yoo, Zhang, Dongsheng, Thadhani, Ravi I., Karumanchi, S. Ananth, Rigby, Alan C., Kang, Peter M.

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Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins von Furie, Barbara C, Huang, Mingdong, Rigby, Alan C, Morelli, Xavier, Grant, Marianne A, Huang, Guiqing, Furie, Bruce, Seaton, Barbara

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Solution Structure of the Guanine Nucleotide-binding STAS Domain of SLC26-related SulP Protein Rv1739c from Mycobacterium tuberculosis von Sharma, Alok K., Ye, Liwen, Baer, Christina E., Shanmugasundaram, Kumaran, Alber, Tom, Alper, Seth L., Rigby, Alan C.

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PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors von Stokes, Michael E, Calvo, Veronica, Fujisawa, Sho, Dudgeon, Crissy, Huang, Sharon, Ballal, Nupur, Shen, Leyi, Gasparek, Jennifer, Betzenhauser, Matthew, Taylor, Simon J, Staschke, Kirk A, Rigby, Alan C, Mulvihill, Mark J, Bose, Nandita, Lightcap, Eric S, Surguladze, David

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Discovery of HC-7366: An Orally Bioavailable and Efficacious GCN2 Kinase Activator von Thomson, Christopher G., Aicher, Thomas D., Cheng, Weiwei, Du, Hongwen, Dudgeon, Crissy, Li, An-Hu, Li, Baozhong, Lightcap, Eric, Luo, Diheng, Mulvihill, Mark, Pan, Pengwei, Rahemtulla, Benjamin F., Rigby, Alan C., Sherborne, Bradley, Sood, Sanjeev, Surguladze, David, Talbot, Eric P. A., Tameire, Feven, Taylor, Simon, Wang, Yi, Wojnarowicz, Paulina, Xiao, Fenfen, Ramurthy, Savithri

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Netropsin improves survival from endotoxaemia by disrupting HMGA1 binding to the NOS2 promoter von Grant, Marianne A, Baron, Rebecca M, Macias, Alvaro A, Layne, Matthew D, Perrella, Mark A, Rigby, Alan C

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Critical role for the Ets transcription factor ELF-1 in the development of tumor angiogenesis von Huang, Xuling, Brown, Courtney, Ni, Weihua, Maynard, Elizabeth, Rigby, Alan C., Oettgen, Peter

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STAS Domain Structure and Function von Sharma, Alok K., Rigby, Alan C., Alper, Seth L.

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Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors von Calvo, Veronica, Surguladze, David, Li, An-Hu, Surman, Matthew D., Malibhatla, Srikanth, Bandaru, Madhavarao, Jonnalagadda, Suresh Krishna, Adarasandi, Ravi, Velmala, Madhusudhan, Singireddi, Durga Rama Prasad, Velpuri, Mahendar, Nareddy, Bhaskar Reddy, Sastry, Visweswara, Mandati, Chiranjeevi, Guguloth, Rambabu, Siddiqui, Shapi, Patil, Basanagoud S., Chad, Elena, Wolfley, Jennifer, Gasparek, Jennifer, Feldman, Kirsten, Betzenhauser, Matthew, Wiens, Brent, Koszelak-Rosenblum, Mary, Zhu, Guangyu, Du, Hongwen, Rigby, Alan C., Mulvihill, Mark J.

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Heparin-induced cis- and trans-Dimerization Modes of the Thrombospondin-1 N-terminal Domain von Tan, Kemin, Duquette, Mark, Liu, Jin-huan, Shanmugasundaram, Kumaran, Joachimiak, Andrzej, Gallagher, John T., Rigby, Alan C., Wang, Jia-huai, Lawler, Jack

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On the nucleation of amyloid β‐protein monomer folding von Lazo, Noel D., Grant, Marianne A., Condron, Margaret C., Rigby, Alan C., Teplow, David B.

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Discovery of small molecule inhibitors to Krüppel-like factor 10 (KLF10): implications for modulation of T regulatory cell differentiation von Khedkar, Santosh A, Sun, Xinghui, Rigby, Alan C, Feinberg, Mark W

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Withanolide A and Asiatic Acid Modulate Multiple Targets Associated with Amyloid-β Precursor Protein Processing and Amyloid-β Protein Clearance von Patil, Sachin P, Maki, Sarah, Khedkar, Santosh A, Rigby, Alan C, Chan, Christina

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