Optimization of a Collagen-Targeted PET Probe for Molecular Imaging of Pulmonary Fibrosis von Désogère, Pauline, Tapias, Luis F, Rietz, Tyson A, Rotile, Nicholas, Blasi, Francesco, Day, Helen, Elliott, Justin, Fuchs, Bryan C, Lanuti, Michael, Caravan, Peter

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Fragment-based screening of programmed death ligand 1 (PD-L1) von Perry, Evan, Mills, Jonathan J., Zhao, Bin, Wang, Feng, Sun, Qi, Christov, Plamen P., Tarr, James C., Rietz, Tyson A., Olejniczak, Edward T., Lee, Taekyu, Fesik, Stephen

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Fragment-Based Discovery of Small Molecules Bound to T‑Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3) von Rietz, Tyson A, Teuscher, Kevin B, Mills, Jonathan J, Gogliotti, Rocco D, Lepovitz, Lance T, Scaggs, W. Rush, Yoshida, Keisuke, Luong, Kelvin, Lee, Taekyu, Fesik, Stephen W

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Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization von Teuscher, Kevin B, Meyers, Kenneth M, Wei, Qiangqiang, Mills, Jonathan J, Tian, Jianhua, Alvarado, Joseph, Sai, Jiqing, Van Meveren, Mayme, South, Taylor M, Rietz, Tyson A, Zhao, Bin, Moore, William J, Stott, Gordon M, Tansey, William P, Lee, Taekyu, Fesik, Stephen W

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Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core von Tian, Jianhua, Teuscher, Kevin B, Aho, Erin R, Alvarado, Joseph R, Mills, Jonathan J, Meyers, Kenneth M, Gogliotti, Rocco D, Han, Changho, Macdonald, Jonathan D, Sai, Jiqing, Shaw, J. Grace, Sensintaffar, John L, Zhao, Bin, Rietz, Tyson A, Thomas, Lance R, Payne, William G, Moore, William J, Stott, Gordon M, Kondo, Jumpei, Inoue, Masahiro, Coffey, Robert J, Tansey, William P, Stauffer, Shaun R, Lee, Taekyu, Fesik, Stephen W

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Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats von Blasi, Francesco, Oliveira, Bruno L, Rietz, Tyson A, Rotile, Nicholas J, Naha, Pratap C, Cormode, David P, Izquierdo-Garcia, David, Catana, Ciprian, Caravan, Peter

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3D molecular MR imaging of liver fibrosis and response to rapamycin therapy in a bile duct ligation rat model von Farrar, Christian T, DePeralta, Danielle K, Day, Helen, Rietz, Tyson A, Wei, Lan, Lauwers, Gregory Y, Keil, Boris, Subramaniam, Arun, Sinskey, Anthony J, Tanabe, Kenneth K, Fuchs, Bryan C, Caravan, Peter

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Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models von Teuscher, Kevin B, Chowdhury, Somenath, Meyers, Kenneth M, Tian, Jianhua, Sai, Jiqing, Van Meveren, Mayme, South, Taylor M, Sensintaffar, John L, Rietz, Tyson A, Goswami, Soumita, Wang, Jing, Grieb, Brian C, Lorey, Shelly L, Howard, Gregory C, Liu, Qi, Moore, William J, Stott, Gordon M, Tansey, William P, Lee, Taekyu, Fesik, Stephen W

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Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111In- and 68Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats von Oliveira, Bruno L, Blasi, Francesco, Rietz, Tyson A, Rotile, Nicholas J, Day, Helen, Caravan, Peter

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Fragment-Based Screen of SARS-CoV‑2 Papain-like Protease (PLpro) von Taylor, Ashley J., Amporndanai, Kangsa, Rietz, Tyson A., Zhao, Bin, Thiruvaipati, Anusha, Wei, Qiangqiang, South, Taylor M., Crow, Mackenzie M., Apakama, Chideraa, Sensintaffar, John L., Phan, Jason, Lee, Taekyu, Fesik, Stephen W.

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Fibrin-Targeted PET Probes for the Detection of Thrombi von Ciesienski, Katie L, Yang, Yan, Ay, Ilknur, Chonde, Daniel B, Loving, Galen S, Rietz, Tyson A, Catana, Ciprian, Caravan, Peter

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Effect of Chelate Type and Radioisotope on the Imaging Efficacy of 4 Fibrin-Specific PET Probes von Blasi, Francesco, Oliveira, Bruno L, Rietz, Tyson A, Rotile, Nicholas J, Day, Helen, Looby, Richard J, Ay, Ilknur, Caravan, Peter

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In vivo molecular imaging of thrombosis and thrombolysis using a fibrin-binding positron emission tomographic probe von Ay, Ilknur, Blasi, Francesco, Rietz, Tyson A, Rotile, Nicholas J, Kura, Sreekanth, Brownell, Anna Liisa, Day, Helen, Oliveira, Bruno L, Looby, Richard J, Caravan, Peter

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Hexameric Mn(II) dendrimer as MRI contrast agent von Zhu, Jiang, Gale, Eric M, Atanasova, Iliyana, Rietz, Tyson A, Caravan, Peter

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Hexameric MnII Dendrimer as MRI Contrast Agent von Zhu, Jiang, Gale, Eric M., Atanasova, Iliyana, Rietz, Tyson A., Caravan, Peter

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Radiation Dosimetry of the Fibrin-Binding Probe ⁶⁴Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats von Blasi, Francesco, Oliveira, Bruno L, Rietz, Tyson A, Rotile, Nicholas J, Day, Helen, Naha, Pratap C, Cormode, David P, Izquierdo-Garcia, David, Catana, Ciprian, Caravan, Peter

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Hexameric Mn II Dendrimer as MRI Contrast Agent von Zhu, Jiang, Gale, Eric M., Atanasova, Iliyana, Rietz, Tyson A., Caravan, Peter

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Combined magnetic resonance elastography and collagen molecular magnetic resonance imaging accurately stage liver fibrosis in a rat model von Zhu, Bo, Wei, Lan, Rotile, Nicholas, Day, Helen, Rietz, Tyson, Farrar, Christian T., Lauwers, Gregory Y., Tanabe, Kenneth K., Rosen, Bruce, Fuchs, Bryan C., Caravan, Peter

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Fragment-based screening and discovery of small molecule ligands for TIGIT and TIM-3 von Rietz, Tyson Alexander

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A potent pan-sarbecovirus neutralizing antibody resilient to epitope diversification von Rosen, Laura E, Tortorici, M Alejandra, De Marco, Anna, Pinto, Dora, Foreman, William B, Taylor, Ashley L, Park, Young-Jun, Bohan, Dana, Rietz, Tyson, Errico, John M, Hauser, Kevin, Dang, Ha V, Chartron, Justin W, Giurdanella, Martina, Cusumano, Giuseppe, Saliba, Christian, Zatta, Fabrizia, Sprouse, Kaitlin R, Addetia, Amin, Zepeda, Samantha K, Brown, Jack, Lee, Jimin, Dellota, Jr, Exequiel, Rajesh, Anushka, Noack, Julia, Tao, Qiqing, DaCosta, Yvonne, Tsu, Brian, Acosta, Rima, Subramanian, Sambhavi, de Melo, Guilherme Dias, Kergoat, Lauriane, Zhang, Ivy, Liu, Zhuoming, Guarino, Barbara, Schmid, Michael A, Schnell, Gretja, Miller, Jessica L, Lempp, Florian A, Czudnochowski, Nadine, Cameroni, Elisabetta, Whelan, Sean P J, Bourhy, Hervé, Purcell, Lisa A, Benigni, Fabio, di Iulio, Julia, Pizzuto, Matteo Samuele, Lanzavecchia, Antonio, Telenti, Amalio, Snell, Gyorgy, Corti, Davide, Veesler, David, Starr, Tyler N

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