Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell–Mediated Cytotoxicity Against Hepatocellular Carcinoma von Hage, Carina, Hoves, Sabine, Strauss, Léanne, Bissinger, Stefan, Prinz, Ylva, Pöschinger, Thomas, Kiessling, Fabian, Ries, Carola H.

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Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab von Pickl, M, Ries, C H

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In vitro generation of monocyte-derived macrophages under serum-free conditions improves their tumor promoting functions von Rey-Giraud, Flora, Hafner, Mathias, Ries, Carola H

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Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy von Cannarile, Michael A, Weisser, Martin, Jacob, Wolfgang, Jegg, Anna-Maria, Ries, Carola H, Rüttinger, Dominik

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Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles von Cianciaruso, Chiara, Beltraminelli, Tim, Duval, Florent, Nassiri, Sina, Hamelin, Romain, Mozes, André, Gallart-Ayala, Hector, Ceada Torres, Gerardo, Torchia, Bruno, Ries, Carola H, Ivanisevic, Julijana, De Palma, Michele

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Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy von Ries, Carola H., Cannarile, Michael A., Hoves, Sabine, Benz, Jörg, Wartha, Katharina, Runza, Valeria, Rey-Giraud, Flora, Pradel, Leon P., Feuerhake, Friedrich, Klaman, Irina, Jones, Tobin, Jucknischke, Ute, Scheiblich, Stefan, Kaluza, Klaus, Gorr, Ingo H., Walz, Antje, Abiraj, Keelara, Cassier, Philippe A., Sica, Antonio, Gomez-Roca, Carlos, de Visser, Karin E., Italiano, Antoine, Le Tourneau, Christophe, Delord, Jean-Pierre, Levitsky, Hyam, Blay, Jean-Yves, Rüttinger, Dominik

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Fibroblasts Influence Survival and Therapeutic Response in a 3D Co-Culture Model von Majety, Meher, Pradel, Leon P, Gies, Manuela, Ries, Carola H

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Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response von Salvagno, Camilla, Ciampricotti, Metamia, Tuit, Sander, Hau, Cheei-Sing, van Weverwijk, Antoinette, Coffelt, Seth B., Kersten, Kelly, Vrijland, Kim, Kos, Kevin, Ulas, Thomas, Song, Ji-Ying, Ooi, Chia-Huey, Rüttinger, Dominik, Cassier, Philippe A., Jonkers, Jos, Schultze, Joachim L., Ries, Carola H., de Visser, Karin E.

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Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity von Hoves, Sabine, Ooi, Chia-Huey, Wolter, Carsten, Sade, Hadassah, Bissinger, Stefan, Schmittnaegel, Martina, Ast, Oliver, Giusti, Anna M, Wartha, Katharina, Runza, Valeria, Xu, Wei, Kienast, Yvonne, Cannarile, Michael A, Levitsky, Hyam, Romagnoli, Solange, De Palma, Michele, Rüttinger, Dominik, Ries, Carola H

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Exploring the experiences of siblings of adults with intellectual/developmental disabilities during the COVID‐19 pandemic von Redquest, B. K., Tint, A., Ries, H., Lunsky, Y.

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Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy von Kashyap, Abhishek S., Schmittnaegel, Martina, Rigamonti, Nicolò, Pais-Ferreira, Daniela, Mueller, Philipp, Buchi, Melanie, Ooi, Chia-Huey, Kreuzaler, Matthias, Hirschmann, Petra, Guichard, Alan, Rieder, Natascha, Bill, Ruben, Herting, Frank, Kienast, Yvonne, Dirnhofer, Stefan, Klein, Christian, Hoves, Sabine, Ries, Carola H., Corse, Emily, De Palma, Michele, Zippelius, Alfred

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T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells von Marigo, Ilaria, Zilio, Serena, Desantis, Giacomo, Mlecnik, Bernhard, Agnellini, Andrielly H.R., Ugel, Stefano, Sasso, Maria Stella, Qualls, Joseph E., Kratochvill, Franz, Zanovello, Paola, Molon, Barbara, Ries, Carola H., Runza, Valeria, Hoves, Sabine, Bilocq, Amélie M., Bindea, Gabriela, Mazza, Emilia M.C., Bicciato, Silvio, Galon, Jérôme, Murray, Peter J., Bronte, Vincenzo

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Macrophage Susceptibility to Emactuzumab (RG7155) Treatment von Pradel, Leon P, Ooi, Chia-Huey, Romagnoli, Solange, Cannarile, Michael A, Sade, Hadassah, Rüttinger, Dominik, Ries, Carola H

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The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models von Maser, Ilona-Petra, Hoves, Sabine, Bayer, Christa, Heidkamp, Gordon, Nimmerjahn, Falk, Eckmann, Jan, Ries, Carola H.

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Characterizing responsive and refractory orthotopic mouse models of hepatocellular carcinoma in cancer immunotherapy von Hage, Carina, Hoves, Sabine, Ashoff, Mailin, Schandl, Veronika, Hört, Stefan, Rieder, Natascha, Heichinger, Christian, Berrera, Marco, Ries, Carola H, Kiessling, Fabian, Pöschinger, Thomas

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Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression von Galletti, Giovanni, Scielzo, Cristina, Barbaglio, Federica, Rodriguez, Tania Véliz, Riba, Michela, Lazarevic, Dejan, Cittaro, Davide, Simonetti, Giorgia, Ranghetti, Pamela, Scarfò, Lydia, Ponzoni, Maurilio, Rocchi, Martina, Corti, Angelo, Anselmo, Achille, van Rooijen, Nico, Klein, Christian, Ries, Carola H., Ghia, Paolo, De Palma, Michele, Caligaris-Cappio, Federico, Bertilaccio, Maria Teresa Sabrina

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Tumor-Microenvironment Characterization of the MB49 Non-Muscle-Invasive Bladder-Cancer Orthotopic Model towards New Therapeutic Strategies von Domingos-Pereira, Sonia, Sathiyanadan, Karthik, Polak, Lenka, Haefliger, Jacques-Antoine, Schmittnaegel, Martina, Ries, Carola H, Jichlinski, Patrice, Roth, Beat, Derré, Laurent, Nardelli-Haefliger, Denise

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T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells von Marigo, Ilaria, Zilio, Serena, Desantis, Giacomo, Mlecnik, Bernhard, Agnellini, Andrielly H.R., Ugel, Stefano, Sasso, Maria Stella, Qualls, Joseph E., Kratochvill, Franz, Zanovello, Paola, Molon, Barbara, Ries, Carola H., Runza, Valeria, Hoves, Sabine, Bilocq, Amélie M., Bindea, Gabriela, Mazza, Emilia M.C., Bicciato, Silvio, Galon, Jérôme, Murray, Peter J., Bronte, Vincenzo

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Periostin Limits Tumor Response to VEGFA Inhibition von Keklikoglou, Ioanna, Kadioglu, Ece, Bissinger, Stefan, Langlois, Benoît, Bellotti, Axel, Orend, Gertraud, Ries, Carola H., De Palma, Michele

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Tumor-associated macrophages promote intratumoral conversion of conventional CD4+ T cells into regulatory T cells via PD-1 signalling von Kos, Kevin, Salvagno, Camilla, Wellenstein, Max D., Aslam, Muhammad A., Meijer, Denize A., Hau, Cheei-Sing, Vrijland, Kim, Kaldenbach, Daphne, Raeven, Elisabeth A.M., Schmittnaegel, Martina, Ries, Carola H., de Visser, Karin E.

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