New Approaches to Sepsis: Molecular Diagnostics and Biomarkers von REINHART, Konrad, BAUER, Michael, RIEDEMANN, Niels C, HARTOG, Christiane S

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The late phase of sepsis is characterized by an increased microbiological burden and death rate von Otto, Gordon P, Sossdorf, Maik, Claus, Ralf A, Rödel, Jürgen, Menge, Katja, Reinhart, Konrad, Bauer, Michael, Riedemann, Niels C

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Evaluation of a polymerase chain reaction assay for pathogen detection in septic patients under routine condition: an observational study von Bloos, Frank, Sachse, Svea, Kortgen, Andreas, Pletz, Mathias W, Lehmann, Marc, Straube, Eberhard, Riedemann, Niels C, Reinhart, Konrad, Bauer, Michael

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Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-con... von Vlaar, Alexander P J, Witzenrath, Martin, van Paassen, Pieter, Heunks, Leo M A, Mourvillier, Bruno, de Bruin, Sanne, Lim, Endry H T, Brouwer, Matthijs C, Tuinman, Pieter R, Saraiva, José F K, Marx, Gernot, Lobo, Suzana M, Boldo, Rodrigo, Simon-Campos, Jesus A, Cornet, Alexander D, Grebenyuk, Anastasia, Engelbrecht, Johannes M, Mukansi, Murimisi, Jorens, Philippe G, Zerbib, Robert, Rückinger, Simon, Pilz, Korinna, Guo, Renfeng, van de Beek, Diederik, Riedemann, Niels C

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Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis von Recknagel, Peter, Gonnert, Falk A, Westermann, Martin, Lambeck, Sandro, Lupp, Amelie, Rudiger, Alain, Dyson, Alex, Carré, Jane E, Kortgen, Andreas, Krafft, Christoph, Popp, Jürgen, Sponholz, Christoph, Fuhrmann, Valentin, Hilger, Ingrid, Claus, Ralf A, Riedemann, Niels C, Wetzker, Reinhard, Singer, Mervyn, Trauner, Michael, Bauer, Michael

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The anti‐C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID‐19 von Vlaar, Alexander P. J., Lim, Endry H. T., Bruin, Sanne, Rückinger, Simon, Pilz, Korinna, Brouwer, Matthijs C., Guo, Ren‐Feng, Heunks, Leo M. A., Busch, Matthias H., Paassen, Pieter, Riedemann, Niels C., Beek, Diederik

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Controlling the anaphylatoxin C5a in diseases requires a specifically targeted inhibition von Riedemann, Niels C, Habel, Maria, Ziereisen, Jana, Hermann, Marlen, Schneider, Conny, Wehling, Cyrill, Kirschfink, Michael, Kentouche, Karim, Guo, Renfeng

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Renal effects of synthetic colloids and crystalloids in patients with severe sepsis: A prospective sequential comparison von Bayer, Ole, Reinhart, Konrad, Sakr, Yasser, Kabisch, Bjoern, Kohl, Matthias, Riedemann, Niels C, Bauer, Michael, Settmacher, Utz, Hekmat, Khosro, Hartog, Christiane S

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Family satisfaction in the intensive care unit: a quantitative and qualitative analysis von Schwarzkopf, Daniel, Behrend, Susanne, Skupin, Helga, Westermann, Isabella, Riedemann, Niels C., Pfeifer, Rüdiger, Günther, Albrecht, Witte, Otto W., Reinhart, Konrad, Hartog, Christiane S.

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Perioperative Fluid Therapy With Tetrastarch and Gelatin in Cardiac Surgery—A Prospective Sequential Analysis von Bayer, Ole, Schwarzkopf, Daniel, Doenst, Torsten, Cook, Deborah, Kabisch, Bjoern, Schelenz, Christoph, Bauer, Michael, Riedemann, Niels C, Sakr, Yasser, Kohl, Matthias, Reinhart, Konrad, Hartog, Christiane S

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The enigma of sepsis von Riedemann, Niels C, Guo, Ren-Feng, Ward, Peter A

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Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys von Sun, Shihui, Zhao, Guangyu, Liu, Chenfeng, Fan, Wei, Zhou, Xiaojun, Zeng, Lin, Guo, Yan, Kou, Zhihua, Yu, Hong, Li, Junfeng, Wang, Renxi, Li, Yan, Schneider, Conny, Habel, Maria, Riedemann, Niels C., Du, Lanying, Jiang, Shibo, Guo, Renfeng, Zhou, Yusen

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Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled tr... von Vlaar, Alexander P J, de Bruin, Sanne, Busch, Matthias, Timmermans, Sjoerd A M E G, van Zeggeren, Ingeborg E, Koning, Rutger, ter Horst, Liora, Bulle, Esther B, van Baarle, Frank E H P, van de Poll, Marcel C G, Kemper, E Marleen, van der Horst, Iwan C C, Schultz, Marcus J, Horn, Janneke, Paulus, Frederique, Bos, Lieuwe D, Wiersinga, W Joost, Witzenrath, Martin, Rueckinger, Simon, Pilz, Korinna, Brouwer, Matthijs C, Guo, Ren-Feng, Heunks, Leo, van Paassen, Pieter, Riedemann, Niels C, van de Beek, Diederik

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Novel strategies for the treatment of sepsis von Ward, Peter A, Riedemann, Niels C, Guo, Ren-Feng

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Heterogeneity of treatment effect of vilobelimab in COVID-19: a secondary analysis of a randomised controlled trial von van Amstel, Rombout B E, Slim, Marleen A, Lim, Endry H T, Rückinger, Simon, Seymour, Christopher W, Burnett, Bruce P, Bos, Lieuwe D J, van Vught, Lonneke A, Riedemann, Niels C, van de Beek, Diederik, Vlaar, Alexander P J

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A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a von Hünniger, Kerstin, Bieber, Kristin, Martin, Ronny, Lehnert, Teresa, Figge, Marc Thilo, Löffler, Jürgen, Guo, Ren-Feng, Riedemann, Niels C, Kurzai, Oliver

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End-of-life care in the intensive care unit: A patient-based questionnaire of intensive care unit staff perception and relatives’ psychological response von Hartog, Christiane S, Schwarzkopf, Daniel, Riedemann, Niels C, Pfeifer, Ruediger, Guenther, Albrecht, Egerland, Kati, Sprung, Charles L, Hoyer, Heike, Gensichen, Jochen, Reinhart, Konrad

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Protective Effects of IL-6 Blockade in Sepsis Are Linked to Reduced C5a Receptor Expression von Riedemann, Niels C, Neff, Thomas A, Guo, Ren-Feng, Bernacki, Kurt D, Laudes, Ines J, Sarma, J. Vidya, Lambris, John D, Ward, Peter A

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Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill,  invasively mechanically ventilated COVID-19 patien... von Lim, Endry H. T., Vlaar, Alexander P. J., de Bruin, Sanne, Rückinger, Simon, Thielert, Claus, Habel, Maria, Guo, Renfeng, Burnett, Bruce P., Dickinson, James, Brouwer, Matthijs C., Riedemann, Niels C., van de Beek, Diederik

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Regulatory Effects of iNOS on Acute Lung Inflammatory Responses in Mice von Speyer, Cecilia L., Neff, Thomas A., Warner, Roscoe L., Guo, Ren-Feng, Sarma, J. Vidya, Riedemann, Niels C., Murphy, Megan E., Murphy, Hedwig S., Ward, Peter A.

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