G Protein-Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus von Riddy, Darren M, Delerive, Philippe, Summers, Roger J, Sexton, Patrick M, Langmead, Christopher J

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Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research von Riddy, Darren M, Goy, Emily, Delerive, Philippe, Summers, Roger J, Sexton, Patrick M, Langmead, Christopher J

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New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery von Park, Julia, Langmead, Christopher J, Riddy, Darren M

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Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates von Rinne, Maiju K., Urvas, Lauri, Mandrika, Ilona, Fridmanis, Dāvids, Riddy, Darren M., Langmead, Christopher J., Kukkonen, Jyrki P., Xhaard, Henri

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Investigating the molecular mechanisms through which FTY720‐P causes persistent S1P1 receptor internalization von Sykes, David A, Riddy, Darren M, Stamp, Craig, Bradley, Michelle E, McGuiness, Neil, Sattikar, Afrah, Guerini, Danilo, Rodrigues, Ines, Glaenzel, Albrecht, Dowling, Mark R, Mullershausen, Florian, Charlton, Steven J

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Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms von Riddy, Darren M, Kammoun, Helene L, Murphy, Andrew J, Bosnyak-Gladovic, Sanja, De la Fuente Gonzalez, Rocio, Merlin, Jon, Ziemann, Mark, Fabb, Stewart, Pierce, Tracie L, Diepenhorst, Natalie, Rueda, Patricia, El-Osta, Assam, Gautier, Jean-Francois, Venteclef, Nicolas, Charman, William N, Christopoulos, Arthur, Sexton, Patrick M, Summers, Roger J, Febbraio, Mark A, Delerive, Philippe, Langmead, Christopher J

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Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors von Merlin, Jon, Park, Julia, Vandekolk, Teresa H, Fabb, Stewart A, Allinne, Jeanne, Summers, Roger J, Langmead, Christopher J, Riddy, Darren M

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Acetylcholine Muscarinic M4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents von Walker, Leigh C., Berizzi, Alice E., Chen, Nicola A., Rueda, Patricia, Perreau, Victoria M., Huckstep, Katherine, Srisontiyakul, Jirawoot, Govitrapong, Piyarat, Xiaojian, Jia, Lindsley, Craig W., Jones, Carrie K., Riddy, Darren M., Christopoulos, Arthur, Langmead, Christopher J., Lawrence, Andrew J.

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Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy von Sykes, David A, Bradley, Michelle E, Riddy, Darren M, Willard, Elizabeth, Reilly, John, Miah, Asadh, Bauer, Carsten, Watson, Simon J, Sandham, David A, Dubois, Gerald, Charlton, Steven J

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Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H3 receptor antagonists von Riddy, Darren M., Cook, Anna E., Shackleford, David M., Pierce, Tracie L., Mocaer, Elisabeth, Mannoury la Cour, Clotilde, Sors, Aurore, Charman, William N., Summers, Roger J., Sexton, Patrick M., Christopoulos, Arthur, Langmead, Christopher J.

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Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H 3 receptor antagonists von Riddy, Darren M, Cook, Anna E, Shackleford, David M, Pierce, Tracie L, Mocaer, Elisabeth, Mannoury la Cour, Clotilde, Sors, Aurore, Charman, William N, Summers, Roger J, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J

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Isoform-Specific Biased Agonism of Histamine H3 Receptor Agonists von Riddy, Darren M, Cook, Anna E, Diepenhorst, Natalie A, Bosnyak, Sanja, Brady, Ryan, Mannoury la Cour, Clotilde, Mocaer, Elisabeth, Summers, Roger J, Charman, William N, Sexton, Patrick M, Christopoulos, Arthur, Langmead, Christopher J

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Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor Antagonists von Riddy, Darren M, Valant, Celine, Rueda, Patricia, Charman, William N, Sexton, Patrick M, Summers, Roger J, Christopoulos, Arthur, Langmead, Christopher J

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Isoform-Specific Biased Agonism of Histamine H 3 Receptor Agonists von Riddy, Darren M., Cook, Anna E., Diepenhorst, Natalie A., Bosnyak, Sanja, Brady, Ryan, Mannoury la Cour, Clotilde, Mocaer, Elisabeth, Summers, Roger J., Charman, William N., Sexton, Patrick M., Christopoulos, Arthur, Langmead, Christopher J.

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Bone marrow transplantation and RNAseq analysis of Gpr21−/− monocytes reveals reduced migratory function and downregulation of inflammatory genes von Riddy, Darren M., Kammoun, Helene, Bosnyak-Gladovic, Sanja, Ziemann, Mark, Summers, Roger J., Sexton, Patrick M., Murphy, Andrew J., Langmead, Chris J.

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Acetylcholine Muscarinic M 4 Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents von Walker, Leigh C, Berizzi, Alice E, Chen, Nicola A, Rueda, Patricia, Perreau, Victoria M, Huckstep, Katherine, Srisontiyakul, Jirawoot, Govitrapong, Piyarat, Xiaojian, Jia, Lindsley, Craig W, Jones, Carrie K, Riddy, Darren M, Christopoulos, Arthur, Langmead, Christopher J, Lawrence, Andrew J

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Investigating the molecular mechanisms through which FTY 720‐ P causes persistent S1P 1 receptor internalization von Sykes, David A, Riddy, Darren M, Stamp, Craig, Bradley, Michelle E, McGuiness, Neil, Sattikar, Afrah, Guerini, Danilo, Rodrigues, Ines, Glaenzel, Albrecht, Dowling, Mark R, Mullershausen, Florian, Charlton, Steven J

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