Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties von Richter, Hans G.F., Benson, G.M., Bleicher, K.H., Blum, D., Chaput, E., Clemann, N., Feng, S., Gardes, C., Grether, U., Hartman, P., Kuhn, B., Martin, R.E., Plancher, J.-M., Rudolph, M.G., Schuler, F., Taylor, S.

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Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes von Richter, Hans G.F., Benson, Gregory M., Blum, Denise, Chaput, Evelyne, Feng, Song, Gardes, Christophe, Grether, Uwe, Hartman, Peter, Kuhn, Bernd, Martin, Rainer E., Plancher, Jean-Marc, Rudolph, Markus G., Schuler, Franz, Taylor, Sven, Bleicher, Konrad H.

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2-Phenoxy-nicotinamides are Potent Agonists at the Bile Acid Receptor GPBAR1 (TGR5) von Martin, Rainer E., Bissantz, Caterina, Gavelle, Olivier, Kuratli, Christoph, Dehmlow, Henrietta, Richter, Hans G. F., Obst Sander, Ulrike, Erickson, Shawn D., Kim, Kyungjin, Pietranico-Cole, Sherrie Lynn, Alvarez-Sánchez, Rubén, Ullmer, Christoph

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Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists von Dehmlow, Henrietta, Alvarez Sánchez, Rubén, Bachmann, Stephan, Bissantz, Caterina, Bliss, Fritz, Conde-Knape, Karin, Graf, Martin, Martin, Rainer E., Obst Sander, Ulrike, Raab, Susanne, Richter, Hans G.F., Sewing, Sabine, Sprecher, Urs, Ullmer, Christoph, Mattei, Patrizio

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Cover Picture: 2-Phenoxy-nicotinamides are Potent Agonists at the Bile Acid Receptor GPBAR1 (TGR5) (ChemMedChem 4/2013) von Martin, Rainer E., Bissantz, Caterina, Gavelle, Olivier, Kuratli, Christoph, Dehmlow, Henrietta, Richter, Hans G. F., Obst Sander, Ulrike, Erickson, Shawn D., Kim, Kyungjin, Pietranico-Cole, Sherrie Lynn, Alvarez-Sánchez, Rubén, Ullmer, Christoph

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Design, Synthesis, and Evaluation of 2β-Alkenyl Penam Sulfone Acids as Inhibitors of β-Lactamases von Richter, Hans G. F, Angehrn, Peter, Hubschwerlen, Christian, Kania, Malgosia, Page, Malcolm G. P, Specklin, Jean-Luc, Winkler, Fritz K

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Synthesis and Structure−Activity Relationship of (Lactamylvinyl)cephalosporins Exhibiting Activity against Staphylococci, Pneumococci, and Enterococci von Heinze-Krauss, Ingrid, Angehrn, Peter, Guerry, Philippe, Hebeisen, Paul, Hubschwerlen, Christian, Kompis, Ivan, Page, Malcolm G. P, Richter, Hans G. F, Runtz, Valérie, Stalder, Henri, Weiss, Urs, Wei, Chung-Chen

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Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2 -a]pyrazines as potent and selective 5-HT2C receptor agonists von RICHTER, Hans G. F, ADAMS, D. R, KNIGHT, A. R, MALCOLM, C. S, MATTEI, P, MISRA, A, MIZRAHI, J, MONCK, N. J. T, PLANCHER, J.-M, ROEVER, S, ROFFEY, J. R. A, TAYLOR, S, BENARDEAU, A, VICKERS, S. P, BICKERDIKE, M. J, BENTLEY, J. M, BLENCH, T. J, CLIFFE, I. A, DOURISH, C, HEBEISEN, P, KENNETT, G. A

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Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists von Richter, Hans G F, Adams, D R, Benardeau, A, Bickerdike, M J, Bentley, J M, Blench, T J, Cliffe, I A, Dourish, C, Hebeisen, P, Kennett, G A, Knight, A R, Malcolm, C S, Mattei, P, Misra, A, Mizrahi, J, Monck, N J T, Plancher, J-M, Roever, S, Roffey, J R A, Taylor, S, Vickers, S P

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Synthesis and biological evaluation of novel hexahydro- pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT sub(2C) receptor agonists von Richter, Hans GF, Adams, DR, Benardeau, A, Bickerdike, MJ, Bentley, J M, Blench, T J, Cliffe, IA, Dourish, C, Hebeisen, P, Kennett, G A, Knight, A R, Malcolm, C S, Mattei, P, Misra, A, Mizrahi, J, Monck, NJT, Plancher, J-M, Roever, S, Roffey, JRA, Taylor, S, Vickers, S P

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Vinylpyrrolidinone cephalosporin derivatives von ANGEHRN PETER, HEINZE-KRAUSS INGRID, RICHTER HANS G. F

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Vinylpyrrolidone cephalosporin derivatives von ANGEHRN PETER, HEINZE-KRAUSS INGRID, RICHTER, HANS, G. F

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VINYL-PIRROLIDINONE-CEPHALOSPORIN DERIVATIVES von ANGEHRN,PETER, HEINZE-KRAUSS,INGRID, RICHTER,HANS G. F

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Derivado de cefalosporina vinilpirrolidinona von PETER ANGEHRN, INGRID HEINZE-KRAUSS, HANS G. F. RICHTER

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DERIVADOS DE VINILPIRROLIDINON-CEFALOSPORINA von HEINZE-KRAUSS, INGRID, RICHTER, HANS G. F, ANGEHRN, PETER

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3-[2-OXO-N-HETEROCYCL-3-YLIDENEMETHYL]-CEPHALOSPORIN DERIVATIVES von HEINZE-KRAUSS, INGRID, ANGEHRN, PETER, RICHTER, HANS G F

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Propenyl cephalosporin derivatives and process for the manufacture thereof von ANGEHRN PETER, HEINZE-KRAUSS INGRID, GOETSCHI ERWIN, RICHTER HANS G. F

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Propenyl cephalosporin derivatives and process for the manufacture thereof von Angehrn, Peter, Götschi, Erwin, Heinze-Krauss, Ingrid, Richter, Hans G. F

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VINYLPYRROLIDINONE CEPHALOSPORIN DERIVATIVES von ANGEHRN PETER, HEINZE-KRAUSS INGRID, RICHTER HANS G F

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Vinylpyrrolidinon cephalosporin derivatives von PETER ANGEHRN, HANS G. F. RICHTER, INGRID HINZE-KRAUSS

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