Cloning, mechanistic and functional analysis of a fungal sterol C24-methyltransferase implicated in brassicasterol biosynthesis von Pereira, Maristela, Song, Zhihong, Santos-Silva, Ludier Kesser, Richards, Mathew H., Nguyen, Thi Thuy Minh, Liu, JiaLin, de Almeida Soares, Celia Maria, da Silva Cruz, Aline Helena, Ganapathy, Kulothungan, Nes, W. David

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The challenge of unprecedented floods and droughts in risk management von Kreibich, H, Van Loon, AF, Schroeter, K, Ward, PJ, Mazzoleni, M, Sairam, N, Abeshu, GW, Agafonova, S, AghaKouchak, A, Aksoy, H, Alvarez-Garreton, C, Aznar, B, Balkhi, L, Barendrecht, MH, Biancamaria, S, Bos-Burgering, L, Bradley, C, Budiyono, Y, Buytaert, W, Capewell, L, Carlson, H, Cavus, Y, Couasnon, A, Coxon, G, Daliakopoulos, I, De Ruiter, MC, Delus, C, Erfurt, M, Esposito, G, Francois, D, Frappart, F, Freer, J, Frolova, N, Gain, AK, Grillakis, M, Grima, JO, Guzman, DA, Huning, LS, Ionita, M, Kharlamov, M, Khoi, DN, Kieboom, N, Kireeva, M, Koutroulis, A, Lavado-Casimiro, W, Li, H-Y, LLasat, MC, Macdonald, D, Mard, J, Mathew-Richards, H, McKenzie, A, Mejia, A, Mendiondo, EM, Mens, M, Mobini, S, Mohor, GS, Nagavciuc, V, Thanh, N-D, Thi, TNH, Pham, TTN, Petrucci, O, Hong, QN, Quintana-Segui, P, Razavi, S, Ridolfi, E, Riegel, J, Sadik, MS, Savelli, E, Sazonov, A, Sharma, S, Sorensen, J, Souza, FAA, Stahl, K, Steinhausen, M, Stoelzle, M, Szalinska, W, Tang, Q, Tian, F, Tokarczyk, T, Tovar, C, Tran, TVT, Van Huijgevoort, MHJ, Van Vliet, MTH, Vorogushyn, S, Wagener, T, Wang, Y, Wendt, DE, Wickham, E, Yang, L, Zambrano-Bigiarini, M, Bloschl, G, Di Baldassarre, G

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Dose-Adjusted EPOCH-R Compared With R-CHOP as Frontline Therapy for Diffuse Large B-Cell Lymphoma: Clinical Outcomes of the Phase III Intergroup Trial Alliance/CALGB 50303 von Bartlett, Nancy L, Wilson, Wyndham H, Jung, Sin-Ho, Hsi, Eric D, Maurer, Matthew J, Pederson, Levi D, Polley, Mei-Yin C, Pitcher, Brandelyn N, Cheson, Bruce D, Kahl, Brad S, Friedberg, Jonathan W, Staudt, Louis M, Wagner-Johnston, Nina D, Blum, Kristie A, Abramson, Jeremy S, Reddy, Nishitha M, Winter, Jane N, Chang, Julie E, Gopal, Ajay K, Chadburn, Amy, Mathew, Susan, Fisher, Richard I, Richards, Kristy L, Schöder, Heiko, Zelenetz, Andrew D, Leonard, John P

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Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension von Hutchinson, Peter J, Kolias, Angelos G, Timofeev, Ivan S, Corteen, Elizabeth A, Czosnyka, Marek, Timothy, Jake, Anderson, Ian, Bulters, Diederik O, Belli, Antonio, Eynon, C. Andrew, Wadley, John, Mendelow, A. David, Mitchell, Patrick M, Wilson, Mark H, Critchley, Giles, Sahuquillo, Juan, Unterberg, Andreas, Servadei, Franco, Teasdale, Graham M, Pickard, John D, Menon, David K, Murray, Gordon D, Kirkpatrick, Peter J

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Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs von Lee, S Hong, Ripke, Stephan, Neale, Benjamin M, Faraone, Stephen V, Purcell, Shaun M, Perlis, Roy H, Mowry, Bryan J, Thapar, Anita, Goddard, Michael E, Witte, John S, Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A, Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E, Asherson, Philip, Azevedo, Maria H, Backlund, Lena, Badner, Judith A, Bailey, Anthony J, Banaschewski, Tobias, Barchas, Jack D, Barnes, Michael R, Barrett, Thomas B, Bass, Nicholas, Battaglia, Agatino, Bauer, Michael, Bayés, Mònica, Bellivier, Frank, Bergen, Sarah E, Berrettini, Wade, Betancur, Catalina, Bettecken, Thomas, Biederman, Joseph, Binder, Elisabeth B, Black, Donald W, Blackwood, Douglas H R, Bloss, Cinnamon S, Boehnke, Michael, Boomsma, Dorret I, Breen, Gerome, Breuer, René, Bruggeman, Richard, Cormican, Paul, Buccola, Nancy G, Buitelaar, Jan K, Bunney, William E, Buxbaum, Joseph D, Byerley, William F, Byrne, Enda M, Caesar, Sian, Cahn, Wiepke, Cantor, Rita M, Casas, Miguel, Chakravarti, Aravinda, Chambert, Kimberly, Choudhury, Khalid, Cichon, Sven, Cloninger, C Robert, Collier, David A, Cook, Edwin H, Coon, Hilary, Cormand, Bru, Corvin, Aiden, Coryell, William H, Craig, David W, Craig, Ian W, Crosbie, Jennifer, Cuccaro, Michael L, Curtis, David, Czamara, Darina, Datta, Susmita, Dawson, Geraldine, Day, Richard, De Geus, Eco J, Degenhardt, Franziska, Djurovic, Srdjan, Donohoe, Gary J, Doyle, Alysa E, Duan, Jubao, Dudbridge, Frank, Duketis, Eftichia, Ebstein, Richard P, Edenberg, Howard J, Elia, Josephine, Ennis, Sean, Etain, Bruno, Fanous, Ayman, Farmer, Anne E, Ferrier, I Nicol, Flickinger, Matthew, Fombonne, Eric, Foroud, Tatiana, Frank, Josef, Franke, Barbara, Fraser, Christine

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Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer von Ross, L., Eisen, A., Elsafy, F., Fielding, A., Friedman, S., Gianni, L., Phillips, K.-A., Singer, C.F., Toi, M., Park, Y.H., Yang, H., Mailliez, A., Nagy, T., Sonke, G.S., Sun, Q., Colleoni, M.A., Kaufman, B., Cameron, D., Campbell, C., Sevelda, Paul, Öhler, Leopold, Rumpold, Holger, Rautenberg, Beate, Boadle, David, Mackey, John, Niraula, Saroj, Randal d’Hondt, Papadimitriou, Konstantinos, Lazzaro, Mauricio Fernández, Pilnik, Norma, Varela, Mirta, Darsow, Maren, Park-Simon, Tjoung-Won, Terhaag, Jürgen, Salat, Christoph, Dieterich, Max, García Sáenz, José Ángel, Lanza, Angels Arcusa, Quiroga, Vanesa, Jañez, Noelia Martínez, Crusades, Gema Llort, Rodríguez, César, Cretella, Elisabetta, Jegannathen, Apurna, Ishida, Kazushige, Watanabe, Junichiro, Takada, Masahiro, Nakamura, Seigo, Aogi, Kenjiro, Tsugawa, Koichiro, Seaward, Samantha A., Carney, Jennifer Fu, Bobolis, Kristie A., Eisenberg, Peter D., Hofstatter, Erin W., McCarron, Edward C., Herbolsheimer, Pia, Meisel, Jane L., Jones, Cheryl F., Spector, David M., Lo, Shelly S., Cristofanilli, Massimo, Hahn, Olwen M., Oliff, Ira A., Ansari, Bilal, Sharma, Priyanka, Armstrong, Deborah K., VanderWoude, Amy, Friday, Bret E.B., T, Benjamin, Kuzma, Charles S., Radford, James E., Soori, Gamini S., Vogel, Victor G., Wilkinson, Mary, Qamar, Rubina, Loman, Niklas, Silander, Gustav, Abreu, Miguel, Ciruelos Gil, Eva María, Bermejo de las Heras, Begoña, Busch, Steffi, Thomalla, Jörg, Altena, Renske, Chen, Shou-Tung, Huang, Chiun-Sheng, Yeh, Dah-Cherng, Pottier, Virginie, Yang, Hongjian, Fu, Peifen, Wang, Yongsheng, Fan, Zhimin, Landherr, László, Yerushalmi, Rinat, Conte, Pierfranco, Ciccarese, Mariangela, Mackiewicz, Jacek, Kalinka, Ewa, Im, Seock-Ah, Lee, Kyoung Eun

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Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients von Mack, Michael J, Leon, Martin B, Thourani, Vinod H, Makkar, Raj, Kodali, Susheel K, Russo, Mark, Kapadia, Samir R, Malaisrie, S. Chris, Cohen, David J, Pibarot, Philippe, Leipsic, Jonathon, Hahn, Rebecca T, Blanke, Philipp, Williams, Mathew R, McCabe, James M, Brown, David L, Babaliaros, Vasilis, Goldman, Scott, Szeto, Wilson Y, Genereux, Philippe, Pershad, Ashish, Pocock, Stuart J, Alu, Maria C, Webb, John G, Smith, Craig R

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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis von Vujkovic, Marijana, Keaton, Jacob M., Lynch, Julie A., Miller, Donald R., Zhou, Jin, Tcheandjieu, Catherine, Huffman, Jennifer E., Assimes, Themistocles L., Lorenz, Kimberly, Zhu, Xiang, Hilliard, Austin T., Judy, Renae L., Huang, Jie, Lee, Kyung M., Klarin, Derek, Pyarajan, Saiju, Danesh, John, Melander, Olle, Rasheed, Asif, Mallick, Nadeem H., Hameed, Shahid, Qureshi, Irshad H., Afzal, Muhammad Naeem, Malik, Uzma, Jalal, Anjum, Abbas, Shahid, Sheng, Xin, Gao, Long, Kaestner, Klaus H., Susztak, Katalin, Sun, Yan V., DuVall, Scott L., Cho, Kelly, Lee, Jennifer S., Gaziano, J. Michael, Phillips, Lawrence S., Meigs, James B., Reaven, Peter D., Wilson, Peter W., Edwards, Todd L., Rader, Daniel J., Damrauer, Scott M., O’Donnell, Christopher J., Tsao, Philip S., Chang, Kyong-Mi, Voight, Benjamin F., Saleheen, Danish

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Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study von Cleynen, Isabelle, PhD, Boucher, Gabrielle, MSc, Jostins, Luke, PhD, Schumm, L Philip, MA, Zeissig, Sebastian, PhD, Ahmad, Tariq, PhD, Andersen, Vibeke, Prof, Andrews, Jane M, Prof, Annese, Vito, MD, Brand, Stephan, Prof, Brant, Steven R, MD, Cho, Judy H, Prof, Daly, Mark J, Prof, Dubinsky, Marla, MD, Duerr, Richard H, Prof, Ferguson, Lynnette R, Prof, Franke, Andre, Prof, Gearry, Richard B, Prof, Goyette, Philippe, PhD, Hakonarson, Hakon, Prof, Halfvarson, Jonas, MD, Hov, Johannes R, PhD, Huang, Hailang, PhD, Kennedy, Nicholas A, PhD, Kupcinskas, Limas, Prof, Lawrance, Ian C, Prof, Lee, James C, PhD, Satsangi, Jack, Prof, Schreiber, Stephan, Prof, Théâtre, Emilie, PhD, van der Meulen-de Jong, Andrea E, MD, Weersma, Rinse K, Prof, Wilson, David C, Prof, Parkes, Miles, PhD, Vermeire, Severine, Prof, Rioux, John D, Prof, Mansfield, John, MD, Silverberg, Mark S, PhD, Radford-Smith, Graham, PhD, McGovern, Dermot P B, Prof, Barrett, Jeffrey C, Dr, Lees, Charlie W, Dr

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Decompressive Craniectomy versus Craniotomy for Acute Subdural Hematoma von Hutchinson, Peter J., Adams, Hadie, Mohan, Midhun, Devi, Bhagavatula I., Uff, Christopher, Hasan, Shumaila, Mee, Harry, Wilson, Mark H., Gupta, Deepak K., Bulters, Diederik, Zolnourian, Ardalan, McMahon, Catherine J., Stovell, Matthew G., Al-Tamimi, Yahia Z., Tewari, Manoj K., Tripathi, Manjul, Thomson, Simon, Viaroli, Edoardo, Belli, Antonio, King, Andrew T., Helmy, Adel E., Timofeev, Ivan S., Pyne, Sarah, Shukla, Dhaval P., Bhat, Dhananjaya I., Maas, Andrew R., Servadei, Franco, Manley, Geoffrey T., Barton, Garry, Turner, Carole, Menon, David K., Gregson, Barbara, Kolias, Angelos G.

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Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease von Fisher, Sheila A, Tremelling, Mark, Anderson, Carl A, Gwilliam, Rhian, Bumpstead, Suzannah, Prescott, Natalie J, Nimmo, Elaine R, Massey, Dunecan, Berzuini, Carlo, Johnson, Christopher, Barrett, Jeffrey C, Cummings, Fraser R, Drummond, Hazel, Lees, Charlie W, Onnie, Clive M, Hanson, Catherine E, Blaszczyk, Katarzyna, Inouye, Mike, Ewels, Philip, Ravindrarajah, Radhi, Keniry, Andrew, Hunt, Sarah, Carter, Martyn, Watkins, Nick, Ouwehand, Willem, Lewis, Cathryn M, Cardon, Lon, Lobo, Alan, Forbes, Alastair, Sanderson, Jeremy, Jewell, Derek P, Mansfield, John C, Deloukas, Panos, Mathew, Christopher G, Parkes, Miles, Satsangi, Jack

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Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years von Mack, Michael J, Leon, Martin B, Thourani, Vinod H, Pibarot, Philippe, Hahn, Rebecca T, Genereux, Philippe, Kodali, Susheel K, Kapadia, Samir R, Cohen, David J, Pocock, Stuart J, Lu, Michael, White, Roseann, Szerlip, Molly, Ternacle, Julien, Malaisrie, S Chris, Herrmann, Howard C, Szeto, Wilson Y, Russo, Mark J, Babaliaros, Vasilis, Smith, Craig R, Blanke, Philipp, Webb, John G, Makkar, Raj

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Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia von Bhatt, Deepak L, Steg, P. Gabriel, Miller, Michael, Brinton, Eliot A, Jacobson, Terry A, Ketchum, Steven B, Doyle, Ralph T, Juliano, Rebecca A, Jiao, Lixia, Granowitz, Craig, Tardif, Jean-Claude, Ballantyne, Christie M

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The Cancer Genome Atlas Pan-Cancer analysis project von Weinstein, John N, Collisson, Eric A, Mills, Gordon B, Shaw, Kenna R Mills, Ozenberger, Brad A, Ellrott, Kyle, Shmulevich, Ilya, Sander, Chris, Stuart, Joshua M

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NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease von Schwerd, T, Bryant, R V, Pandey, S, Capitani, M, Meran, L, Cazier, J-B, Jung, J, Mondal, K, Parkes, M, Mathew, C G, Fiedler, K, McCarthy, D J, Sullivan, P B, Rodrigues, A, Travis, S P L, Moore, C, Sambrook, J, Ouwehand, W H, Roberts, D J, Danesh, J, Russell, R K, Wilson, D C, Kelsen, J R, Cornall, R, Denson, L A, Kugathasan, S, Knaus, U G, Serra, E G, Anderson, C A, Duerr, R H, McGovern, D PB, Cho, J, Powrie, F, Li, V SW, Muise, A M, Uhlig, H H

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Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases von Iglesias, Adriana I., Mishra, Aniket, Vitart, Veronique, Bykhovskaya, Yelena, Höhn, René, Springelkamp, Henriët, Cuellar-Partida, Gabriel, Gharahkhani, Puya, Bailey, Jessica N. Cooke, Willoughby, Colin E., Li, Xiaohui, Yazar, Seyhan, Nag, Abhishek, Khawaja, Anthony P., Polašek, Ozren, Siscovick, David, Mitchell, Paul, Tham, Yih Chung, Haines, Jonathan L., Kearns, Lisa S., Hayward, Caroline, Shi, Yuan, van Leeuwen, Elisabeth M., Taylor, Kent D., Bonnemaijer, Pieter, Rotter, Jerome I., Martin, Nicholas G., Zeller, Tanja, Mills, Richard A., Souzeau, Emmanuelle, Staffieri, Sandra E., Jonas, Jost B., Schmidtmann, Irene, Boutin, Thibaud, Kang, Jae H., Lucas, Sionne E. M., Wong, Tien Yin, Beutel, Manfred E., Wilson, James F., Uitterlinden, André G., Vithana, Eranga N., Foster, Paul J., Hysi, Pirro G., Hewitt, Alex W., Khor, Chiea Chuen, Pasquale, Louis R., Montgomery, Grant W., Klaver, Caroline C. W., Aung, Tin, Pfeiffer, Norbert, Mackey, David A., Hammond, Christopher J., Cheng, Ching-Yu, Craig, Jamie E., Rabinowitz, Yaron S., Wiggs, Janey L., Burdon, Kathryn P., van Duijn, Cornelia M., MacGregor, Stuart

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Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease von Rivas, Manuel A, Beaudoin, Mélissa, Gardet, Agnes, Stevens, Christine, Sharma, Yashoda, Zhang, Clarence K, Boucher, Gabrielle, Ripke, Stephan, Ellinghaus, David, Burtt, Noel, Fennell, Tim, Kirby, Andrew, Latiano, Anna, Goyette, Philippe, Green, Todd, Halfvarson, Jonas, Haritunians, Talin, Korn, Joshua M, Kuruvilla, Finny, Lagacé, Caroline, Neale, Benjamin, Lo, Ken Sin, Schumm, Phil, Törkvist, Leif, Dubinsky, Marla C, Brant, Steven R, Silverberg, Mark S, Duerr, Richard H, Altshuler, David, Gabriel, Stacey, Lettre, Guillaume, Franke, Andre, D'Amato, Mauro, McGovern, Dermot P B, Cho, Judy H, Rioux, John D, Xavier, Ramnik J, Daly, Mark J

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IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes von Momozawa, Yukihide, Dmitrieva, Julia, Théâtre, Emilie, Deffontaine, Valérie, Rahmouni, Souad, Charloteaux, Benoît, Crins, François, Docampo, Elisa, Elansary, Mahmoud, Gori, Ann-Stephan, Lecut, Christelle, Mariman, Rob, Mni, Myriam, Oury, Cécile, Altukhov, Ilya, Alexeev, Dmitry, Aulchenko, Yuri, Amininejad, Leila, Bouma, Gerd, Hoentjen, Frank, Löwenberg, Mark, Oldenburg, Bas, Pierik, Marieke J., vander Meulen-de Jong, Andrea E., Janneke van der Woude, C., Visschedijk, Marijn C., Lathrop, Mark, Hugot, Jean-Pierre, Weersma, Rinse K., De Vos, Martine, Franchimont, Denis, Vermeire, Severine, Kubo, Michiaki, Louis, Edouard, Georges, Michel

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The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines von Agha, Riaz A., Franchi, Thomas, Sohrabi, Catrin, Mathew, Ginimol, Kerwan, Ahmed, Thoma, Achilles, Beamish, Andrew J., Noureldin, Ashraf, Rao, Ashwini, Vasudevan, Baskaran, Challacombe, Ben, Perakath, Benjamin, Kirshtein, Boris, Ekser, Burcin, Pramesh, C.S., Laskin, Daniel M., Machado-Aranda, David, Miguel, Diana, Pagano, Duilio, Millham, Frederick H., Roy, Gaurav, Kadioglu, Huseyin, Nixon, Iain J., Mukherjee, Indraneil, McCaul, James A., Chi-Yong Ngu, James, Albrecht, Joerg, Rivas, Juan Gomez, Raveendran, Kandiah, Derbyshire, Laura, Ather, M. Hammad, Thorat, Mangesh A., Valmasoni, Michele, Bashashati, Mohammad, Chalkoo, Mushtaq, Teo, Nan Zun, Raison, Nicholas, Muensterer, Oliver J., Bradley, Patrick James, Goel, Prabudh, Pai, Prathamesh S., Afifi, Raafat Yahia, Rosin, Richard David, Coppola, Roberto, Klappenbach, Roberto, Wynn, Rolf, De Wilde, Rudy Leon, Surani, Salim, Giordano, Salvatore, Massarut, Samuele, Raja, Shahzad G., Basu, Somprakas, Enam, Syed Ather, Manning, Todd Galvin, Cross, Trent, Karanth, Veena KL, Kasivisvanathan, Veeru, Mei, Zubing

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Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease von Bhatt, Deepak L, Szarek, Michael, Pitt, Bertram, Cannon, Christopher P, Leiter, Lawrence A, McGuire, Darren K, Lewis, Julia B, Riddle, Matthew C, Inzucchi, Silvio E, Kosiborod, Mikhail N, Cherney, David Z.I, Dwyer, Jamie P, Scirica, Benjamin M, Bailey, Clifford J, Díaz, Rafael, Ray, Kausik K, Udell, Jacob A, Lopes, Renato D, Lapuerta, Pablo, Steg, P. Gabriel

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