Combenefit: an interactive platform for the analysis and visualization of drug combinations von Di Veroli, Giovanni Y, Fornari, Chiara, Wang, Dennis, Mollard, Séverine, Bramhall, Jo L, Richards, Frances M, Jodrell, Duncan I

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CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response von Biasci, Daniele, Smoragiewicz, Martin, Connell, Claire M., Wang, Zhikai, Gao, Ya, Thaventhiran, James E. D., Basu, Bristi, Magiera, Lukasz, Johnson, T. Isaac, Bax, Lisa, Gopinathan, Aarthi, Isherwood, Christopher, Gallagher, Ferdia A., Pawula, Maria, Hudecova, Irena, Gale, Davina, Rosenfeld, Nitzan, Barmpounakis, Petros, Popa, Elizabeta Cristina, Brais, Rebecca, Godfrey, Edmund, Mirk, Fraz, Richards, Frances M., Fearon, Douglas T., Janowitz, Tobias, Jodrell, Duncan I.

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Understanding the Complexity of Porous Graphitic Carbon (PGC) Chromatography: Modulation of Mobile-Stationary Phase Interactions Overcomes Loss of Retention and Reduces Variability von Bapiro, Tashinga E, Richards, Frances M, Jodrell, Duncan I

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Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo von Richards, Frances M, Tape, Christopher J, Jodrell, Duncan I, Murphy, Gillian

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Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models von Dunlop, Charles R., Wallez, Yann, Johnson, Timothy Isaac, Bernaldo de Quirós Fernández, Sandra, Durant, Stephen T., Cadogan, Elaine B., Lau, Alan, Richards, Frances M., Jodrell, Duncan I.

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A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level von Koh, Siang-Boon, Mascalchi, Patrice, Rodriguez, Esther, Lin, Yao, Jodrell, Duncan I, Richards, Frances M, Lyons, Scott K

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An automated fitting procedure and software for dose-response curves with multiphasic features von Di Veroli, Giovanni Y., Fornari, Chiara, Goldlust, Ian, Mills, Graham, Koh, Siang Boon, Bramhall, Jo L, Richards, Frances M., Jodrell, Duncan I.

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Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors von Sale, Matthew J., Minihane, Emma, Monks, Noel R., Gilley, Rebecca, Richards, Frances M., Schifferli, Kevin P., Andersen, Courtney L., Davies, Emma J., Vicente, Mario Aladren, Ozono, Eiko, Markovets, Aleksandra, Dry, Jonathan R., Drew, Lisa, Flemington, Vikki, Proia, Theresa, Jodrell, Duncan I., Smith, Paul D., Cook, Simon J.

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Method To Visualize the Intratumor Distribution and Impact of Gemcitabine in Pancreatic Ductal Adenocarcinoma by Multimodal Imaging von Strittmatter, Nicole, Richards, Frances M, Race, Alan M, Ling, Stephanie, Sutton, Daniel, Nilsson, Anna, Wallez, Yann, Barnes, Jennifer, Maglennon, Gareth, Gopinathan, Aarthi, Brais, Rebecca, Wong, Edmond, Serra, Maria Paola, Atkinson, James, Smith, Aaron, Wilson, Joanne, Hamm, Gregory, Johnson, Timothy I, Dunlop, Charles R, Kaistha, Brajesh P, Bunch, Josephine, Sansom, Owen J, Takats, Zoltan, Andrén, Per E, Lau, Alan, Barry, Simon T, Goodwin, Richard J. A, Jodrell, Duncan I

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Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma von Carapuça, Elisabete F, Gemenetzidis, Emilios, Feig, Christine, Bapiro, Tashinga E, Williams, Michael D, Wilson, Abigail S, Delvecchio, Francesca R, Arumugam, Prabhu, Grose, Richard P, Lemoine, Nicholas R, Richards, Frances M, Kocher, Hemant M

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The ATR Inhibitor AZD6738 Synergizes with Gemcitabine In Vitro and In Vivo to Induce Pancreatic Ductal Adenocarcinoma Regression von Wallez, Yann, Dunlop, Charles R, Johnson, Timothy Isaac, Koh, Siang-Boon, Fornari, Chiara, Yates, James W T, Bernaldo de Quirós Fernández, Sandra, Lau, Alan, Richards, Frances M, Jodrell, Duncan I

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SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice von Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A

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CHK1 Inhibition Synergizes with Gemcitabine Initially by Destabilizing the DNA Replication Apparatus von Koh, Siang-Boon, Courtin, Aurélie, Boyce, Richard J, Boyle, Robert G, Richards, Frances M, Jodrell, Duncan I

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Modelling of the cancer cell cycle as a tool for rational drug development: A systems pharmacology approach to cyclotherapy von Jackson, Robert C, Di Veroli, Giovanni Y, Koh, Siang-Boon, Goldlust, Ian, Richards, Frances M, Jodrell, Duncan I

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Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer von Buchholz, Soeren M, Goetze, Robert G, Singh, Shiv K, Ammer-Herrmenau, Christoph, Richards, Frances M, Jodrell, Duncan I, Buchholz, Malte, Michl, Patrick, Ellenrieder, Volker, Hessmann, Elisabeth, Neesse, Albrecht

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Size-tuneable and immunocompatible polymer nanocarriers for drug delivery in pancreatic cancer von Popov, Andrea Bistrovi, Melle, Francesca, Linnane, Emily, González-López, Cristina, Ahmed, Ishtiaq, Parshad, Badri, Franck, Christoph O, Rahmoune, Hassan, Richards, Frances M, Muñoz-Espín, Daniel, Jodrell, Duncan I, Fairen-Jimenez, David, Fruk, Ljiljana

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Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment von Roy-Luzarraga, Marina, Reynolds, Louise E, de Luxán-Delgado, Beatriz, Maiques, Oscar, Wisniewski, Laura, Newport, Emma, Rajeeve, Vinothini, Drake, Rebecca J G, Gómez-Escudero, Jesús, Richards, Frances M, Weller, Céline, Dormann, Christof, Meng, Ya-Ming, Vermeulen, Peter B, Saur, Dieter, Sanz-Moreno, Victoria, Wong, Ping-Pui, Géraud, Cyrill, Cutillas, Pedro R, Hodivala-Dilke, Kairbaan

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Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine von Koh, Siang-Boon, Wallez, Yann, Dunlop, Charles R, Bernaldo de Quirós Fernández, Sandra, Bapiro, Tashinga E, Richards, Frances M, Jodrell, Duncan I

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Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer von Courtin, Aurélie, Richards, Frances M, Bapiro, Tashinga E, Bramhall, Jo L, Neesse, Albrecht, Cook, Natalie, Krippendorff, Ben-Fillippo, Tuveson, David A, Jodrell, Duncan I

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The Montreal Cognitive Assessment (MoCA) - a sensitive screening instrument for detecting cognitive impairment in chronic hemodialysis patients von Tiffin-Richards, Frances E, Costa, Ana S, Holschbach, Bernhard, Frank, Rolf D, Vassiliadou, Athina, Krüger, Thilo, Kuckuck, Karl, Gross, Theresa, Eitner, Frank, Floege, Jürgen, Schulz, Jörg B, Reetz, Kathrin

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