The health effects of vitamin D supplementation: evidence from human studies von Bouillon, Roger, Manousaki, Despoina, Rosen, Cliff, Trajanoska, Katerina, Rivadeneira, Fernando, Richards, J. Brent

Volltext

Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study von Butler-Laporte, Guillaume, Nakanishi, Tomoko, Mooser, Vincent, Morrison, David R., Abdullah, Tala, Adeleye, Olumide, Mamlouk, Noor, Kimchi, Nofar, Afrasiabi, Zaman, Rezk, Nardin, Giliberti, Annarita, Renieri, Alessandra, Chen, Yiheng, Zhou, Sirui, Forgetta, Vincenzo, Richards, J. Brent

Volltext

Obesity and Multiple Sclerosis: A Mendelian Randomization Study von Mokry, Lauren E, Ross, Stephanie, Timpson, Nicholas J, Sawcer, Stephen, Davey Smith, George, Richards, J Brent

Volltext

Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study von Mokry, Lauren E, Ross, Stephanie, Ahmad, Omar S, Forgetta, Vincenzo, Smith, George Davey, Goltzman, David, Leong, Aaron, Greenwood, Celia M T, Thanassoulis, George, Richards, J Brent

Volltext

Genetic architecture: the shape of the genetic contribution to human traits and disease von Timpson, Nicholas J., Greenwood, Celia M. T., Soranzo, Nicole, Lawson, Daniel J., Richards, J. Brent

Volltext

Genetics of osteoporosis from genome-wide association studies: advances and challenges von Richards, J. Brent, Zheng, Hou-Feng, Spector, Tim D.

Volltext

Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases von Chen, Yiheng, Lu, Tianyuan, Pettersson-Kymmer, Ulrika, Stewart, Isobel D., Butler-Laporte, Guillaume, Nakanishi, Tomoko, Cerani, Agustin, Liang, Kevin Y. H., Yoshiji, Satoshi, Willett, Julian Daniel Sunday, Su, Chen-Yang, Raina, Parminder, Greenwood, Celia M. T., Farjoun, Yossi, Forgetta, Vincenzo, Langenberg, Claudia, Zhou, Sirui, Ohlsson, Claes, Richards, J. Brent

Volltext

Connecting Genomics and Proteomics to Identify Protein Biomarkers for Adult and Youth-Onset Type 2 Diabetes: A Two-Sample Mendelian Randomization Study von Ghanbari, Faegheh, Yazdanpanah, Nahid, Yazdanpanah, Mojgan, Richards, J Brent, Manousaki, Despoina

Volltext

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity von Zhou, Sirui, Butler-Laporte, Guillaume, Nakanishi, Tomoko, Morrison, David R., Afilalo, Jonathan, Afilalo, Marc, Laurent, Laetitia, Pietzner, Maik, Kerrison, Nicola, Zhao, Kaiqiong, Brunet-Ratnasingham, Elsa, Henry, Danielle, Kimchi, Nofar, Afrasiabi, Zaman, Rezk, Nardin, Bouab, Meriem, Petitjean, Louis, Guzman, Charlotte, Xue, Xiaoqing, Tselios, Chris, Vulesevic, Branka, Adeleye, Olumide, Abdullah, Tala, Almamlouk, Noor, Chen, Yiheng, Chassé, Michaël, Durand, Madeleine, Paterson, Clare, Normark, Johan, Frithiof, Robert, Lipcsey, Miklós, Hultström, Michael, Greenwood, Celia M. T., Zeberg, Hugo, Langenberg, Claudia, Thysell, Elin, Pollak, Michael, Mooser, Vincent, Forgetta, Vincenzo, Kaufmann, Daniel E., Richards, J. Brent

Volltext

Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19 von Huffman, Jennifer E., Butler-Laporte, Guillaume, Khan, Atlas, Pairo-Castineira, Erola, Drivas, Theodore G., Peloso, Gina M., Nakanishi, Tomoko, Ganna, Andrea, Verma, Anurag, Baillie, J. Kenneth, Kiryluk, Krzysztof, Richards, J. Brent, Zeberg, Hugo

Volltext

Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study von Manousaki, Despoina, Harroud, Adil, Mitchell, Ruth E., Ross, Stephanie, Forgetta, Vince, Timpson, Nicholas J., Smith, George Davey, Polychronakos, Constantin, Richards, J. Brent

Volltext

FAM210A is a novel determinant of bone and muscle structure and strength von Tanaka, Ken-ichiro, Xue, Yingben, Nguyen-Yamamoto, Loan, Morris, John A., Kanazawa, Ippei, Sugimoto, Toshitsugu, Wing, Simon S., Richards, J. Brent, Goltzman, David

Volltext

The undiagnosed disease burden associated with alpha-1 antitrypsin deficiency genotypes von Nakanishi, Tomoko, Forgetta, Vincenzo, Handa, Tomohiro, Hirai, Toyohiro, Mooser, Vincent, Lathrop, G. Mark, Cookson, William O. C. M., Richards, J. Brent

Volltext

Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes von Forgetta, Vincenzo, Manousaki, Despoina, Istomine, Roman, Ross, Stephanie, Tessier, Marie-Catherine, Marchand, Luc, Li, Min, Qu, Hui-Qi, Bradfield, Jonathan P., Grant, Struan F. A., Hakonarson, Hakon, Paterson, Andrew D., Piccirillo, Ciriaco, Polychronakos, Constantin, Richards, J. Brent

Volltext

Mendelian Randomization Studies Do Not Support a Role for Vitamin D in Coronary Artery Disease von Manousaki, Despoina, Mokry, Lauren E, Ross, Stephanie, Goltzman, David, Richards, J Brent

Volltext

Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening von Lu, Tianyuan, Zhou, Sirui, Wu, Haoyu, Forgetta, Vincenzo, Greenwood, Celia M. T., Richards, J. Brent

Volltext

Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis von Kim, Peter Geon, Niroula, Abhishek, Shkolnik, Veronica, McConkey, Marie, Lin, Amy E., Slabicki, Mikolaj, Kemp, John P., Bick, Alexander, Gibson, Christopher J., Griffin, Gabriel, Sekar, Aswin, Brooks, Daniel J., Wong, Waihay J., Cohen, Drew N., Uddin, Md Mesbah, Shin, Wesley J., Pirruccello, James, Tsai, Jonathan M., Agrawal, Mridul, Kiel, Douglas P., Bouxsein, Mary L., Richards, J. Brent, Evans, David M., Wein, Marc N., Charles, Julia F., Jaiswal, Siddhartha, Natarajan, Pradeep, Ebert, Benjamin L.

Volltext

Little evidence for an effect of smoking on multiple sclerosis risk: A mendelian randomization study von Mitchell, Ruth E., Bates, Kirsty, Wootton, Robyn E., Harroud, Adil, Richards, J. Brent, Smith, George Davey, Munafo, Marcus R.

Volltext

The relative contributions of obesity, vitamin D, leptin, and adiponectin to multiple sclerosis risk: A Mendelian randomization mediation analysis von Harroud, Adil, Manousaki, Despoina, Butler-Laporte, Guillaume, Mitchell, Ruth E, Davey Smith, George, Richards, J Brent, Baranzini, Sergio E

Volltext

The Biobanque quebecoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories von Tremblay, Karine, Rousseau, Simon, Zawati, Ma'n H., Auld, Daniel, Chasse, Michael, Coderre, Daniel, Falcone, Emilia Liana, Gauthier, Nicolas, Grandvaux, Nathalie, Gros-Louis, Francois, Jabet, Carole, Joly, Yann, Kaufmann, Daniel E., Laprise, Catherine, Larochelle, Catherine, Maltais, Francois, Mes-Masson, Anne-Marie, Montpetit, Alexandre, Piche, Alain, Richards, J. Brent, Tse, Sze Man, Turgeon, Alexis F., Turecki, Gustavo, Vinh, Donald C., Wang, Han Ting, Mooser, Vincent

Volltext