Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer von Wohlhieter, Corrin A., Richards, Allison L., Uddin, Fathema, Hulton, Christopher H., Quintanal-Villalonga, Àlvaro, Martin, Axel, de Stanchina, Elisa, Bhanot, Umeshkumar, Asher, Marina, Shah, Nisargbhai S., Hayatt, Omar, Buonocore, Darren J., Rekhtman, Natasha, Shen, Ronglai, Arbour, Kathryn C., Donoghue, Mark, Poirier, John T., Sen, Triparna, Rudin, Charles M.

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Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions von Findley, Anthony S., Monziani, Alan, Richards, Allison L., Rhodes, Katherine, Ward, Michelle C., Kalita, Cynthia A., Alazizi, Adnan, Pazokitoroudi, Ali, Sankararaman, Sriram, Wen, Xiaoquan, Lanfear, David E., Pique-Regi, Roger, Gilad, Yoav, Luca, Francesca

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Phase and context shape the function of composite oncogenic mutations von Gorelick, Alexander N., Sánchez-Rivera, Francisco J., Cai, Yanyan, Bielski, Craig M., Biederstedt, Evan, Jonsson, Philip, Richards, Allison L., Vasan, Neil, Penson, Alexander V., Friedman, Noah D., Ho, Yu-Jui, Baslan, Timour, Bandlamudi, Chaitanya, Scaltriti, Maurizio, Schultz, Nikolaus, Lowe, Scott W., Reznik, Ed, Taylor, Barry S.

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Environmental perturbations lead to extensive directional shifts in RNA processing von Richards, Allison L, Watza, Donovan, Findley, Anthony, Alazizi, Adnan, Wen, Xiaoquan, Pai, Athma A, Pique-Regi, Roger, Luca, Francesca

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Gut Microbiota Has a Widespread and Modifiable Effect on Host Gene Regulation von Richards, Allison L, Muehlbauer, Amanda L, Alazizi, Adnan, Burns, Michael B, Findley, Anthony, Messina, Francesco, Gould, Trevor J, Cascardo, Camilla, Pique-Regi, Roger, Blekhman, Ran, Luca, Francesca

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Interactions between glucocorticoid treatment and cis-regulatory polymorphisms contribute to cellular response phenotypes von Maranville, Joseph C, Luca, Francesca, Richards, Allison L, Wen, Xiaoquan, Witonsky, David B, Baxter, Shaneen, Stephens, Matthew, Di Rienzo, Anna

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RNA-DNA Differences Are Generated in Human Cells within Seconds after RNA Exits Polymerase II von Wang, Isabel X., Core, Leighton J., Kwak, Hojoong, Brady, Lauren, Bruzel, Alan, McDaniel, Lee, Richards, Allison L., Wu, Ming, Grunseich, Christopher, Lis, John T., Cheung, Vivian G.

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RNA-DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA von Bar-Yaacov, Dan, Avital, Gal, Levin, Liron, Richards, Allison L, Hachen, Naomi, Rebolledo Jaramillo, Boris, Nekrutenko, Anton, Zarivach, Raz, Mishmar, Dan

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Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center von Rosenbaum, Evan, Antonescu, Cristina R, Smith, Shaleigh, Bradic, Martina, Kashani, Daniel, Richards, Allison L, Donoghue, Mark, Kelly, Ciara M, Nacev, Benjamin, Chan, Jason E, Chi, Ping, Dickson, Mark A, Keohan, Mary L, Gounder, Mrinal M, Movva, Sujana, Avutu, Viswatej, Thornton, Katherine, Zehir, Ahmet, Bowman, Anita S, Singer, Samuel, Tap, William, D’Angelo, Sandra

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A multicenter, randomized, non-comparative, phase II study of nivolumab ± ipilimumab for patients with metastatic sarcoma (Alliance A091401): expansion cohorts and correlative anal... von Seligson, Nathan D, Chen, James L, Goodrich, Austin C, Van Tine, Brian A, Campbell, Jordan D, Richards, Allison L, Antonescu, Cristina R, Liebner, David A, Milhem, Mohammed M, Streicher, Howard, Tap, William D, Schwartz, Gary K, George, Suzanne, D'Angelo, Sandra P

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Tumour lineage shapes BRCA-mediated phenotypes von Jonsson, Philip, Bandlamudi, Chaitanya, Cheng, Michael L., Srinivasan, Preethi, Chavan, Shweta S., Friedman, Noah D., Rosen, Ezra Y., Richards, Allison L., Bouvier, Nancy, Selcuklu, S. Duygu, Bielski, Craig M., Abida, Wassim, Mandelker, Diana, Birsoy, Ozge, Zhang, Liying, Zehir, Ahmet, Donoghue, Mark T. A., Baselga, José, Offit, Kenneth, Scher, Howard I., O’Reilly, Eileen M., Stadler, Zsofia K., Schultz, Nikolaus, Socci, Nicholas D., Viale, Agnes, Ladanyi, Marc, Robson, Mark E., Hyman, David M., Berger, Michael F., Solit, David B., Taylor, Barry S.

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Multi-institutional analysis of aneuploidy and outcomes to chemoradiation and durvalumab in stage III non-small cell lung cancer von Alessi, Joao V, Price, Adam, Richards, Allison L, Ricciuti, Biagio, Wang, Xinan, Elkrief, Arielle, Pecci, Federica, Di Federico, Alessandro, Gandhi, Malini M, Lebow, Emily S, Santos, Patricia Mae G, Thor, Maria, Rimner, Andreas, Schoenfeld, Adam J, Chaft, Jamie E, Johnson, Bruce E, Gomez, Daniel R, Awad, Mark M, Shaverdian, Narek

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Genetic, functional and molecular features of glucocorticoid receptor binding von Luca, Francesca, Maranville, Joseph C, Richards, Allison L, Witonsky, David B, Stephens, Matthew, Di Rienzo, Anna

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Widespread RNA and DNA Sequence Differences in the Human Transcriptome von Li, Mingyao, Wang, Isabel X., Li, Yun, Bruzel, Alan, Richards, Allison L., Toung, Jonathan M., Cheung, Vivian G.

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Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy von Walmsley, Charlotte S., Jonsson, Philip, Cheng, Michael L., McBride, Sean, Kaeser, Christopher, Vargas, Herbert Alberto, Laudone, Vincent, Taylor, Barry S., Kappagantula, Rajya, Baez, Priscilla, Richards, Allison L., Noronha, Anne Marie, Perera, Dilmi, Berger, Michael, Solit, David B., Iacobuzio-Donahue, Christine A., Scher, Howard I., Donoghue, Mark T. A., Abida, Wassim, Schram, Alison M.

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Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation von Rudin, Charles M., Balli, David, Lai, W. Victoria, Richards, Allison L., Nguyen, Evelyn, Egger, Jacklynn V., Choudhury, Noura J., Sen, Triparna, Chow, Andrew, Poirier, John T., Geese, William J., Hellmann, Matthew D., Forslund, Ann

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The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer von Chow, Andrew, Uddin, Fathema Z., Liu, Michael, Dobrin, Anton, Nabet, Barzin Y., Mangarin, Levi, Lavin, Yonit, Rizvi, Hira, Tischfield, Sam E., Quintanal-Villalonga, Alvaro, Chan, Joseph M., Shah, Nisargbhai, Allaj, Viola, Manoj, Parvathy, Mattar, Marissa, Meneses, Maximiliano, Landau, Rebecca, Ward, Mariana, Kulick, Amanda, Kwong, Charlene, Wierzbicki, Matthew, Yavner, Jessica, Egger, Jacklynn, Chavan, Shweta S., Farillas, Abigail, Holland, Aliya, Sridhar, Harsha, Ciampricotti, Metamia, Hirschhorn, Daniel, Guan, Xiangnan, Richards, Allison L., Heller, Glenn, Mansilla-Soto, Jorge, Sadelain, Michel, Klebanoff, Christopher A., Hellmann, Matthew D., Sen, Triparna, de Stanchina, Elisa, Wolchok, Jedd D., Merghoub, Taha, Rudin, Charles M.

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Genetic and transcriptional analysis of human host response to healthy gut microbiota von Richards, Allison L, Burns, Michael B, Alazizi, Adnan, Barreiro, Luis B, Pique-Regi, Roger, Blekhman, Ran, Luca, Francesca

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High-throughput allele-specific expression across 250 environmental conditions von Moyerbrailean, Gregory A, Richards, Allison L, Kurtz, Daniel, Kalita, Cynthia A, Davis, Gordon O, Harvey, Chris T, Alazizi, Adnan, Watza, Donovan, Sorokin, Yoram, Hauff, Nancy, Zhou, Xiang, Wen, Xiaoquan, Pique-Regi, Roger, Luca, Francesca

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The context-specific role of germline pathogenicity in tumorigenesis von Srinivasan, Preethi, Bandlamudi, Chaitanya, Jonsson, Philip, Kemel, Yelena, Chavan, Shweta S., Richards, Allison L., Penson, Alexander V., Bielski, Craig M., Fong, Christopher, Syed, Aijazuddin, Jayakumaran, Gowtham, Prasad, Meera, Hwee, Jason, Sumer, Selcuk Onur, de Bruijn, Ino, Li, Xiang, Gao, JianJiong, Schultz, Nikolaus, Cambria, Roy, Galle, Jesse, Mukherjee, Semanti, Vijai, Joseph, Cadoo, Karen A., Carlo, Maria I., Walsh, Michael F., Mandelker, Diana, Ceyhan-Birsoy, Ozge, Shia, Jinru, Zehir, Ahmet, Ladanyi, Marc, Hyman, David M., Zhang, Liying, Offit, Kenneth, Robson, Mark E., Solit, David B., Stadler, Zsofia K., Berger, Michael F., Taylor, Barry S.

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