Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms von Gnudi, Luigi, Coward, Richard J.M, Long, David A

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The Human Glomerular Podocyte Is a Novel Target for Insulin Action von COWARD, Richard J. M, WELSH, Gavin I, MATHIESON, Peter W, SALEEM, Moin A, JING YANG, TASMAN, Candida, LENNON, Rachel, KOZIELL, Ania, SATCHELL, Simon, HOLMAN, Geoffrey D, KERJASCHKI, Dontscho, TAVARE, Jeremy M

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Nephrin Is Critical for the Action of Insulin on Human Glomerular Podocytes von COWARD, Richard J. M, WELSH, Gavin I, KOZIELL, Ania, HUSSAIN, Sagair, LENNON, Rachel, LAN NI, TAVARE, Jeremy M, MATHIESON, Peter W, SALEEM, Moin A

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Insulin Signaling to the Glomerular Podocyte Is Critical for Normal Kidney Function von Welsh, Gavin I., Hale, Lorna J., Eremina, Vera, Jeansson, Marie, Maezawa, Yoshiro, Lennon, Rachel, Pons, Deborah A., Owen, Rachel J., Satchell, Simon C., Miles, Mervyn J., Caunt, Christopher J., McArdle, Craig A., Pavenstädt, Hermann, Tavaré, Jeremy M., Herzenberg, Andrew M., Kahn, C. Ronald, Mathieson, Peter W., Quaggin, Susan E., Saleem, Moin A., Coward, Richard J.M.

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Advances in our understanding of the pathogenesis of glomerular thrombotic microangiopathy von Keir, Lindsay, Coward, Richard J. M.

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Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress von Garner, Kathryn L., Betin, Virginie M. S., Pinto, Vanda, Graham, Mark, Abgueguen, Emmanuelle, Barnes, Matt, Bedford, David C., McArdle, Craig A., Coward, Richard J. M.

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The insulin receptor and the kidney von Hale, Lorna J, Coward, Richard J.M

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An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles von Barreiro, Karina, Lay, Abigail C., Leparc, German, Tran, Van Du T., Rosler, Marcel, Dayalan, Lusyan, Burdet, Frederic, Ibberson, Mark, Coward, Richard J. M., Huber, Tobias B., Krämer, Bernhard K., Delic, Denis, Holthofer, Harry

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Contrasting consequences of podocyte insulin-like growth factor 1 receptor inhibition von Hurcombe, Jennifer A., Barrington, Fern, Marchetti, Micol, Betin, Virginie M.S., Bowen, Emily E., Lay, Abigail C., Ni, Lan, Dayalan, Lusyan, Pope, Robert J.P., Brinkkoetter, Paul T., Holzenberger, Martin, Welsh, Gavin I., Coward, Richard J.M.

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Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, podocin, and CD2 associated protein in cultured human podocytes von COWARD, Richard J. M, FOSTER, Rebecca R, PATTON, David, LAN NI, LENNON, Rachel, BATES, David O, HARPER, Steven J, MATHIESON, Peter W, SALEEM, Moin A

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Ethnic differences in kidney function in childhood: the Born in Bradford Cohort Renal Study von Ziauddeen, Nida, Jeffrey, Robin F, Waiblinger, Dagmar, Fraser, Simon D S, Alwan, Nisreen A, Yuen, Ho M, Azad, Rafaq, Mason, Dan, Wright, John, Coward, Richard J M, Roderick, Paul J

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MicroRNAs and their delivery in diabetic fibrosis von Wonnacott, Alexa, Denby, Laura, Coward, Richard J.M., Fraser, Donald J., Bowen, Timothy

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The Evolving Importance of Insulin Signaling in Podocyte Health and Disease von Lay, Abigail C, Coward, Richard J M

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IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes von Lay, Abigail C., Hale, Lorna J., Stowell-Connolly, Holly, Pope, Robert J. P., Nair, Viji, Ju, Wenjun, Marquez, Eva, Rollason, Ruth, Hurcombe, Jenny A., Hayes, Bryony, Roberts, Timothy, Gillam, Lawrence, Allington, Jonathan, Nelson, Robert G., Kretzler, Matthias, Holly, Jeff M. P., Perks, Claire M., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.

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Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor von Lay, Abigail C., Hurcombe, Jenny A., Betin, Virginie M. S., Barrington, Fern, Rollason, Ruth, Ni, Lan, Gillam, Lawrence, Pearson, Grace M. E., Østergaard, Mette V., Hamidi, Hellyeh, Lennon, Rachel, Welsh, Gavin I., Coward, Richard J. M.

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DBA2J db/db mice are susceptible to early albuminuria and glomerulosclerosis that correlate with systemic insulin resistance von Østergaard, Mette V, Pinto, Vanda, Stevenson, Kirsty, Worm, Jesper, Fink, Lisbeth N, Coward, Richard J M

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Clinical and genetic analysis of patients with cystinuria in the United Kingdom von Rhodes, Hannah L, Yarram-Smith, Laura, Rice, Sarah J, Tabaksert, Ayla, Edwards, Noel, Hartley, Alice, Woodward, Mark N, Smithson, Sarah L, Tomson, Charles, Welsh, Gavin I, Williams, Margaret, Thwaites, David T, Sayer, John A, Coward, Richard J M

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A role for NPY-NPY2R signaling in albuminuric kidney disease von Lay, Abigail C., Barrington, A. Fern, Hurcombe, Jenny A., Ramnath, Raina D., Graham, Mark, Lewis, Philip A., Wilson, Marieangela C., Heesom, Kate J., Butler, Matthew J., Perrett, Rebecca M., Neal, Chris R., Herbert, Eleanor, Mountjoy, Edward, Atan, Denize, Nair, Viji, Ju, Wenjun, Nelson, Robert G., Kretzler, Matthias, Satchell, Simon C., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.

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Outcome monitoring and risk stratification after cardiac procedure in neonates, infants, children and young adults born with congenital heart disease: protocol for a multicentre pr... von Baquedano, Mai, de Jesus, Samantha E, Rapetto, Filippo, Murphy, Gavin J, Angelini, Gianni, Benedetto, Umberto, Caldas, Patricia, Srivastava, Prashant K, Uzun, Orhan, Luyt, Karen, Gonzalez Corcia, Cecilia, Taliotis, Demetris, Stoica, Serban, Lawlor, Deborah A, Bamber, Andrew R, Perry, Alison, Skeffington, Katie L, Omeje, Ikenna, Pappachan, John, Mumford, Andrew D, Coward, Richard J M, Kenny, Damien, Caputo, Massimo

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Ethnic differences in kidney function in childhood: the Born in Bradford Cohort Renal Study [version 2; peer review: 1 approved, 2 approved with reservations] von Simon D.S. Fraser, Dan Mason, Dagmar Waiblinger, Ho M. Yuen, John Wright, Nisreen A. Alwan, Paul J. Roderick, Richard J.M. Coward, Rafaq Azad, Robin F. Jeffrey, Nida Ziauddeen

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