Cancer metabolism: a therapeutic perspective von Martinez-Outschoorn, Ubaldo E., Peiris-Pagés, Maria, Pestell, Richard G., Sotgia, Federica, Lisanti, Michael P.

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CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells von VELASCO-VELAZQUEZ, Marco, XUANMAO JIAO, DE LA FUENTE, Marisol, PESTELL, Timothy G, ERTEL, Adam, LISANTI, Michael P, PESTELL, Richard G

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Recent advances of highly selective CDK4/6 inhibitors in breast cancer von Xu, Hanxiao, Yu, Shengnan, Liu, Qian, Yuan, Xun, Mani, Sridhar, Pestell, Richard G, Wu, Kongming

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CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angioge... von Capparelli, Claudia, Chiavarina, Barbara, Whitaker-Menezes, Diana, Pestell, Timothy G., Pestell, Richard G., Hulit, James, Andò, Sebastiano, Howell, Anthony, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.

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Recent advances of bispecific antibodies in solid tumors von Yu, Shengnan, Li, Anping, Liu, Qian, Yuan, Xun, Xu, Hanxiao, Jiao, Dechao, Pestell, Richard G, Han, Xinwei, Wu, Kongming

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Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production von Capparelli, Claudia, Guido, Carmela, Whitaker-Menezes, Diana, Bonuccelli, Gloria, Balliet, Renee, Pestell, Timothy G., Goldberg, Allison F., Pestell, Richard G., Howell, Anthony, Sneddon, Sharon, Birbe, Ruth, Tsirigos, Aristotelis, Martinez-Outschoorn, Ubaldo, Sotgia, Federica, Lisanti, Michael P.

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Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production von Guido, Carmela, Whitaker-Menezes, Diana, Capparelli, Claudia, Balliet, Renee, Lin, Zhao, Pestell, Richard G., Howell, Anthony, Aquila, Saveria, Andò, Sebastiano, Martinez-Outschoorn, Ubaldo, Sotgia, Federica, Lisanti, Michael P.

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Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism von Bonuccelli, Gloria, Tsirigos, Aristotelis, Whitaker-Menezes, Diana, Pavlides, Stephanos, Pestell, Richard G., Chiavarina, Barbara, Frank, Philippe G., Flomenberg, Neal, Howell, Anthony, Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.

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The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma von Pavlides, Stephanos, Whitaker-Menezes, Diana, Castello-Cros, Remedios, Flomenberg, Neal, Witkiewicz, Agnieszka K., Frank, Philippe G., Casimiro, Mathew C., Wang, Chenguang, Fortina, Paolo, Addya, Sankar, Pestell, Richard G., Martinez-Outschoorn, Ubaldo E., Sotgia, Federica, Lisanti, Michael P.

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CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth von Capparelli, Claudia, Whitaker-Menezes, Diana, Guido, Carmela, Balliet, Renee, Pestell, Timothy G., Howell, Anthony, Sneddon, Sharon, Pestell, Richard G., Martinez-Outschoorn, Ubaldo, Lisanti, Michael P., Sotgia, Federica

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CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion von Jiao, Xuanmao, Velasco-Velázquez, Marco A, Wang, Min, Li, Zhiping, Rui, Hallgeir, Peck, Amy R, Korkola, James E, Chen, Xuelian, Xu, Shaohua, DuHadaway, James B, Guerrero-Rodriguez, Sandra, Addya, Sankar, Sicoli, Daniela, Mu, Zhaomei, Zhang, Gang, Stucky, Andres, Zhang, Xi, Cristofanilli, Massimo, Fatatis, Alessandro, Gray, Joe W, Zhong, Jiang F, Prendergast, George C, Pestell, Richard G

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New Roles of Cyclin D1 von Pestell, Richard G

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DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis von Liu, Qian, Li, Anping, Yu, Shengnan, Qin, Shuang, Han, Na, Pestell, Richard G, Han, Xinwei, Wu, Kongming

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Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms von Sotgia, Federica, Martinez-Outschoorn, Ubaldo E, Howell, Anthony, Pestell, Richard G, Pavlides, Stephanos, Lisanti, Michael P

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Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: Implications for PET imaging of human tumors von Martinez-Outschoorn, Ubaldo E., Lin, Zhao, Trimmer, Casey, Flomenberg, Neal, Wang, Chenguang, Pavlides, Stephanos, Pestell, Richard G., Howell, Anthony, Sotgia, Federica, Lisanti, Michael P

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Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy von Jiao, Xuanmao, Wang, Min, Zhang, Zhao, Li, Zhiping, Ni, Dong, Ashton, Anthony W., Tang, Hsin-Yao, Speicher, David W., Pestell, Richard G.

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Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomic... von Martinez-Outschoorn, Ubaldo E., Prisco, Marco, Ertel, Adam, Tsirigos, Aristotelis, Lin, Zhao, Pavlides, Stephanos, Wang, Chengwang, Flomenberg, Neal, Knudsen, Erik S., Howell, Anthony, Pestell, Richard G., Sotgia, Federica, Lisanti, Michael P

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An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers von Witkiewicz, Agnieszka K, Dasgupta, Abhijit, Sotgia, Federica, Mercier, Isabelle, Pestell, Richard G, Sabel, Michael, Kleer, Celina G, Brody, Jonathan R, Lisanti, Michael P

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Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts von Whitaker-Menezes, Diana, Martinez-Outschoorn, Ubaldo E., Lin, Zhao, Ertel, Adam, Flomenberg, Neal, Witkiewicz, Agnieszka K., Birbe, Ruth, Howell, Anthony, Pavlides, Stephanos, Gandara, Ricardo, Pestell, Richard G., Sotgia, Federica, Philp, Nancy J., Lisanti, Michael P

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Minireview: Cyclin D1: Normal and Abnormal Functions von Fu, Maofu, Wang, Chenguang, Li, Zhiping, Sakamaki, Toshiyuki, Pestell, Richard G

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