Antibody-Drug Conjugate-Based Therapeutics: State of the Science von Birrer, Michael J, Moore, Kathleen N, Betella, Ilaria, Bates, Richard C

Volltext

Targeted inhibition of the molecular chaperone Hsp90 overcomes ALK inhibitor resistance in non-small cell lung cancer von Sang, Jim, Acquaviva, Jaime, Friedland, Julie C, Smith, Donald L, Sequeira, Manuel, Zhang, Chaohua, Jiang, Qin, Xue, Liquan, Lovly, Christine M, Jimenez, John-Paul, Shaw, Alice T, Doebele, Robert C, He, Suqin, Bates, Richard C, Camidge, D Ross, Morris, Stephan W, El-Hariry, Iman, Proia, David A

Volltext

The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer von He, Suqin, Smith, Donald L., Sequeira, Manuel, Sang, Jim, Bates, Richard C., Proia, David A.

Volltext

FGFR3 translocations in bladder cancer: differential sensitivity to HSP90 inhibition based on drug metabolism von Acquaviva, Jaime, He, Suqin, Zhang, Chaohua, Jimenez, John-Paul, Nagai, Masazumi, Sang, Jim, Sequeira, Manuel, Smith, Donald L, Ogawa, Luisa Shin, Inoue, Takayo, Tatsuta, Noriaki, Knowles, Margaret A, Bates, Richard C, Proia, David A

Volltext

Characterisation of subglacial water using a constrained transdimensional Bayesian transient electromagnetic inversion von Killingbeck, Siobhan F, Booth, Adam D, Livermore, Philip W, Bates, C. Richard, West, Landis J

Volltext

Multifaceted intervention by the Hsp90 inhibitor ganetespib (STA-9090) in cancer cells with activated JAK/STAT signaling von Proia, David A, Foley, Kevin P, Korbut, Tim, Sang, Jim, Smith, Don, Bates, Richard C, Liu, Yuan, Rosenberg, Alex F, Zhou, Dan, Koya, Keizo, Barsoum, James, Blackman, Ronald K

Volltext

mTOR inhibition potentiates HSP90 inhibitor activity via cessation of HSP synthesis von Acquaviva, Jaime, He, Suqin, Sang, Jim, Smith, Donald L, Sequeira, Manuel, Zhang, Chaohua, Bates, Richard C, Proia, David A

Volltext

Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease von BELLOVIN, David I, BATES, Richard C, MUZIKANSKY, Alona, RIMM, David L, MERCURIO, Arthur M

Volltext

Ganetespib and HSP90: Translating Preclinical Hypotheses into Clinical Promise von PROIA, David A, BATES, Richard C

Volltext

The HSP90 Inhibitor Ganetespib Alleviates Disease Progression and Augments Intermittent Cyclophosphamide Therapy in the MRL/lpr Mouse Model of Systemic Lupus Erythematosus von Liu, Yuan, Ye, Josephine, Shin Ogawa, Luisa, Inoue, Takayo, Huang, Qin, Chu, John, Bates, Richard C, Ying, Weiwen, Sonderfan, Andrew J, Rao, Patricia E, Zhou, Dan

Volltext

The epithelial–mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis von Bates, Richard C., DeLeo, Michael J., Mercurio, Arthur M.

Volltext

150,000-year palaeoclimate record from northern Ethiopia supports early, multiple dispersals of modern humans from Africa von Lamb, Henry F., Bates, C. Richard, Bryant, Charlotte L., Davies, Sarah J., Huws, Dei G., Marshall, Michael H., Roberts, Helen M., Toland, Harry

Volltext

Overcoming acquired BRAF inhibitor resistance in melanoma via targeted inhibition of Hsp90 with ganetespib von Acquaviva, Jaime, Smith, Donald L, Jimenez, John-Paul, Zhang, Chaohua, Sequeira, Manuel, He, Suqin, Sang, Jim, Bates, Richard C, Proia, David A

Volltext

The epithelial-mesenchymal transition (EMT) and colorectal cancer progression von Bates, Richard C, Mercurio, Arthur M

Volltext

Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids von Bates, Richard C, Mercurio, Arthur M

Volltext

Geophysical Investigation of the Neolithic Calanais Landscape von Bates, C. Richard, Bates, Martin, Gaffney, Chris, Gaffney, Vincent, Raub, Timothy D.

Volltext

A rat retinal damage model predicts for potential clinical visual disturbances induced by Hsp90 inhibitors von Zhou, Dan, Liu, Yuan, Ye, Josephine, Ying, Weiwen, Ogawa, Luisa Shin, Inoue, Takayo, Tatsuta, Noriaki, Wada, Yumiko, Koya, Keizo, Huang, Qin, Bates, Richard C., Sonderfan, Andrew J.

Volltext

Ancient Arms Race: Antiquity's Largest Fortresses and Sasanian Military Networks of Northern Iran: A Joint Fieldwork Project by the Iranian Center for Archaeological Research, The... von Eberhard Sauer, Sauer, Jebrael Nokandeh, Nokandeh, Hamid Omrani Rekavandi, Omrani Rekavandi

Volltext

Preclinical Activity Profile and Therapeutic Efficacy of the HSP90 Inhibitor Ganetespib in Triple-Negative Breast Cancer von PROIA, David A, CHAOHUA ZHANG, SMITH, Donald L, SANG, Jim, BATES, Richard C, EL-HARIRY, Iman, SEQUEIRA, Manuel, JIMENEZ, John-Paul, SUQIN HE, SPECTOR, Neil, SHAPIRO, Geoffrey I, TOLANEY, Sara, NAGAI, Masazumi, ACQUAVIVA, Jaime

Volltext

Transcriptional activation of integrin β6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma von Bates, Richard C., Bellovin, David I., Brown, Courtney, Maynard, Elizabeth, Wu, Bingyan, Kawakatsu, Hisaaki, Sheppard, Dean, Oettgen, Peter, Mercurio, Arthur M.

Volltext