Machine learning model to predict oncologic outcomes for drugs in randomized clinical trials von Schperberg, Alexander V., Boichard, Amélie, Tsigelny, Igor F., Richard, Stéphane B., Kurzrock, Razelle

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Structural basis for specific ligation of the peroxisome proliferator-activated receptor δ von Wu, Chyuan-Chuan, Baiga, Thomas J., Downes, Michael, La Clair, James J., Atkins, Annette R., Richard, Stephane B., Fan, Weiwei, Stockley-Noel, Theresa A., Bowman, Marianne E., Noel, Joseph P., Evans, Ronald M.

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The Crossroads of Precision Medicine and Therapeutic Decision-Making: Use of an Analytical Computational Platform to Predict Response to Cancer Treatments von Boichard, Amelie, Richard, Stephane B., Kurzrock, Razelle

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Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products von Richard, Stéphane B, Kuzuyama, Tomohisa, Noel, Joseph P

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Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities von Kumano, Takuto, Richard, Stéphane B., Noel, Joseph P., Nishiyama, Makoto, Kuzuyama, Tomohisa

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Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses von Liu, Chang-Jun, Deavours, Bettina E, Richard, Stéphane B, Ferrer, Jean-Luc, Blount, Jack W, Huhman, David, Dixon, Richard A, Noel, Joseph P

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Identify drug repurposing candidates by mining the Protein Data Bank von Moriaud, Fabrice, Richard, Stéphane B., Adcock, Stewart A., Chanas-Martin, Laetitia, Surgand, Jean-Sébastien, Ben Jelloul, Marouane, Delfaud, François

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A soluble, magnesium-independent prenyltransferase catalyzes reverse and regular C-prenylations and O-prenylations of aromatic substrates von Haagen, Yvonne, Unsöld, Inge, Westrich, Lucia, Gust, Bertolt, Richard, Stéphane B., Noel, Joseph P., Heide, Lutz

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Structural Basis for the Design of Potent and Species-Specific Inhibitors of 3-Hydroxy-3-Methylglutaryl CoA Synthases von Pojer, Florence, Ferrer, Jean-Luc, Richard, Stéphane B., Nagegowda, Dinesh A., Chye, Mee-Len, Bach, Thomas J., Noel, Joseph P.

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Abstract 2298: Understanding tumor biology complexity in the advanced cancer setting: PreciGENE® platform predictions correlate with exceptional responses to cancer treatment von Boichard, Amelie, Pham, Timothy V., Richard, Stephane B., Kurzrock, Razelle

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Halophilic Adaptation:  Novel Solvent Protein Interactions Observed in the 2.9 and 2.6 Å Resolution Structures of the Wild Type and a Mutant of Malate Dehydrogenase from Haloarcula... von Richard, Stéphane B, Madern, Dominique, Garcin, Elsa, Zaccai, Giuseppe

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Structure of 4-diphosphocytidyl-2-C- methylerythritol synthetase involved in mevalonate- independent isoprenoid biosynthesis von Noel, Joseph P, Richard, Stéphane B, Bowman, Marianne E, Kwiatkowski, Witek, Kang, Ilgu, Chow, Cathy, Lillo, Antonietta M, Cane, David E

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Kinetic Analysis of Escherichia coli 2-C-Methyl-d-erythritol-4-phosphate Cytidyltransferase, Wild Type and Mutants, Reveals Roles of Active Site Amino Acids von Richard, Stéphane B, Lillo, Antonietta M, Tetzlaff, Charles N, Bowman, Marianne E, Noel, Joseph P, Cane, David E

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The Oligomeric States of Haloarcula marismortui Malate Dehydrogenase are Modulated by Solvent Components as Shown by Crystallographic and Biochemical Studies von Irimia, Adriana, Ebel, Christine, Madern, Dominique, Richard, Stéphane B., Cosenza, Lawrence W., Zaccaı̈, Giuseppe, Vellieux, Frédéric M.D.

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Structural basis for specific ligation of the peroxisome proliferator-activated receptor [delta] von Wu, Chyuan-Chuan, Baiga, Thomas J, Downes, Michael, La Clair, James J, Atkins, Annette R, Richard, Stephane B, Fan, Weiwei, Stockley-Noel, Theresa A, Bowman, Marianne E, Noel, Joseph P, Evans, Ronald M

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Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway von Richard, Stéphane B, Ferrer, Jean-Luc, Bowman, Marianne E, Lillo, Antonietta M, Tetzlaff, Charles N, Cane, David E, Noel, Joseph P

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Absence of Substrate Channeling between Active Sites in the Agrobacterium tumefaciens IspDF and IspE Enzymes of the Methyl Erythritol Phosphate Pathway von Lherbet, Christian, Pojer, Florence, Richard, Stéphane B, Noel, Joseph P, Poulter, C. D

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Insights into the Molecular Relationships between Malate and Lactate Dehydrogenases:  Structural and Biochemical Properties of Monomeric and Dimeric Intermediates of a Mutant of Te... von Madern, Dominique, Ebel, Christine, Mevarech, Moshe, Richard, Stéphane B, Pfister, Claude, Zaccai, Giuseppe

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Structure and Mechanism of 2-C-Methyl-d-erythritol 2,4-Cyclodiphosphate Synthase von Richard, Stéphane B., Ferrer, Jean-Luc, Bowman, Marianne E., Lillo, Antonietta M., Tetzlaff, Charles N., Cane, David E., Noel, Joseph P.

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Identify drug repurposing candidates by mining the Protein Data Bank: Computational Methods for Drug Repurposing von MORIAUD, Fabrice, RICHARD, Stéphane B, ADCOCK, Stewart A, CHANAS-MARTIN, Laetitia, SURGAND, Jean-Sébastien, MAROUANE BEN JELLOUL, DELFAUD, François

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