Second-Generation Antiandrogens: From Discovery to Standard of Care in Castration Resistant Prostate Cancer von Rice, Meghan A, Malhotra, Sanjay V, Stoyanova, Tanya

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Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer von Ghoochani, Ali, Hsu, En-Chi, Aslan, Merve, Rice, Meghan A, Nguyen, Holly M, Brooks, James D, Corey, Eva, Paulmurugan, Ramasamy, Stoyanova, Tanya

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Oncogene-mediated metabolic gene signature predicts breast cancer outcome von Aslan, Merve, Hsu, En-Chi, Garcia-Marques, Fernando J., Bermudez, Abel, Liu, Shiqin, Shen, Michelle, West, Meredith, Zhang, Chiyuan Amy, Rice, Meghan A., Brooks, James D., West, Robert, Pitteri, Sharon J., Győrffy, Balázs, Stoyanova, Tanya

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Loss of Notch1 Activity Inhibits Prostate Cancer Growth and Metastasis and Sensitizes Prostate Cancer Cells to Antiandrogen Therapies von Rice, Meghan A, Hsu, En-Chi, Aslan, Merve, Ghoochani, Ali, Su, Austin, Stoyanova, Tanya

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Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1 von Hsu, En-Chi, Rice, Meghan A., Bermudez, Abel, Marques, Fernando Jose Garcia, Aslan, Merve, Liu, Shiqin, Ghoochani, Ali, Zhang, Chiyuan Amy, Chen, Yun-Sheng, Zlitni, Aimen, Kumar, Sahil, Nolley, Rosalie, Habte, Frezghi, Shen, Michelle, Koul, Kashyap, Peehl, Donna M., Zoubeidi, Amina, Gambhir, Sanjiv S., Kunder, Christian A., Pitteri, Sharon J., Brooks, James D., Stoyanova, Tanya

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Plectin is a regulator of prostate cancer growth and metastasis von Buckup, Mark, Rice, Meghan A., Hsu, En-Chi, Garcia-Marques, Fernando, Liu, Shiqin, Aslan, Merve, Bermudez, Abel, Huang, Jiaoti, Pitteri, Sharon J., Stoyanova, Tanya

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Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer von Liu, Shiqin, Shen, Michelle, Hsu, En-Chi, Zhang, Chiyuan Amy, Garcia-Marques, Fernando, Nolley, Rosalie, Koul, Kashyap, Rice, Meghan A., Aslan, Merve, Pitteri, Sharon J., Massie, Charlie, George, Anne, Brooks, James D., Gnanapragasam, Vincent J., Stoyanova, Tanya

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Identification of a 5-gene signature panel for the prediction of prostate cancer progression von Shen, Michelle, García-Marqués, Fernando, Muruganantham, Arvind, Liu, Shiqin, White, James Robert, Bermudez, Abel, Rice, Meghan A., Thompson, Kelsey, Chen, Chun-Liang, Hung, Chia-Nung, Zhang, Zhao, Huang, Tim H., Liss, Michael A., Pienta, Kenneth J., Pitteri, Sharon J., Stoyanova, Tanya

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Quantitative Proteomic Profiling Reveals Key Pathways in the Anticancer Action of Methoxychalcone Derivatives in Triple Negative Breast Cancer von Going, Catherine C, Tailor, Dhanir, Kumar, Vineet, Birk, Alisha M, Pandrala, Mallesh, Rice, Meghan A, Stoyanova, Tanya, Malhotra, Sanjay, Pitteri, Sharon J

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In Vivo Imaging of Methionine Aminopeptidase II for Prostate Cancer Risk Stratification von Xie, Jinghang, Rice, Meghan A, Chen, Zixin, Cheng, Yunfeng, Hsu, En-Chi, Chen, Min, Song, Guosheng, Cui, Liyang, Zhou, Kaixiang, Castillo, Jessa B, Zhang, Chiyuan A, Shen, Bin, Chin, Frederick T, Kunder, Christian A, Brooks, James D, Stoyanova, Tanya, Rao, Jianghong

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Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer von Stoyanova, Tanya, Riedinger, Mireille, Lin, Shu, Faltermeier, Claire M., Smith, Bryan A., Zhang, Kelvin X., Going, Catherine C., Goldstein, Andrew S., Lee, John K., Drake, Justin M., Rice, Meghan A., Hsu, En-Chi, Nowroozizadeh, Behdokht, Castor, Brandon, Orellana, Sandra Y., Blum, Steven M., Cheng, Donghui, Pienta, Kenneth J., Reiter, Robert E., Pitteri, Sharon J., Huang, Jiaoti, Witte, Owen N.

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Targeting AR Variant-Coactivator Interactions to Exploit Prostate Cancer Vulnerabilities von Magani, Fiorella, Peacock, Stephanie O, Rice, Meghan A, Martinez, Maria J, Greene, Ann M, Magani, Pablo S, Lyles, Rolando, Weitz, Jonathan R, Burnstein, Kerry L

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SU086, an inhibitor of HSP90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer von Rice, Meghan A., Kumar, Vineet, Tailor, Dhanir, Garcia-Marques, Fernando Jose, Hsu, En-Chi, Liu, Shiqin, Bermudez, Abel, Kanchustambham, Vijayalakshmi, Shankar, Vishnu, Inde, Zintis, Alabi, Busola Ruth, Muruganantham, Arvind, Shen, Michelle, Pandrala, Mallesh, Nolley, Rosalie, Aslan, Merve, Ghoochani, Ali, Agarwal, Arushi, Buckup, Mark, Kumar, Manoj, Going, Catherine C., Peehl, Donna M., Dixon, Scott J., Zare, Richard N., Brooks, James D., Pitteri, Sharon J., Malhotra, Sanjay V., Stoyanova, Tanya

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Abstract 4917: Therapeutic inhibition of Notch1 in metastatic prostate cancer von Rice, Meghan A., Hsu, En-Chi, Stoyanova, Tanya

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Abstract 2324: A novel oncogene mediated metabolic gene signature predicts breast cancer outcome von Aslan, Merve, Hsu, En-Chi, Marques, Fernando J. Garcia, Bermudez, Abel, Shen, Michelle, Rice, Meghan A., Liu, Shiqin, West, Robert, Pitteri, Sharon J., Győrffy, Balázs, Stoyanova, Tanya

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Loss of Notch1 activity inhibits prostate cancer growth and metastasis and sensitizes prostate cancer cells to anti-androgen therapies von Rice, Meghan A., Hsu, En-Chi, Aslan, Merve, Ghoochani, Ali, Su, Austin, Stoyanova, Tanya

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Direct targeting of RAS in pancreatic ductal adenocarcinoma with RMC-6236, a first-in-class, RAS-selective, orally bioavailable, tri-complex RAS MULTI (ON) inhibitor von Gustafson, W. Clay, Wildes, David, Rice, Meghan A., Lee, Bianca J., Jiang, Jingjing, Wang, Zhengping, Chang, Stephanie, Flagella, Mike, Mu, Yunming, Dinglasan, Nuntana, Nasholm, Nicole, Evans, James W., Seamon, Kyle, Cregg, Jim, Bermingham, Alun, Freilich, Rebecca, Gill, Adrian L., Koltun, Elena, Smith, Jacqueline A, Singh, Mallika

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Abstract 1260: First-in-class, orally bioavailable KRASG12V(ON) tri-complex inhibitors, as single agents and in combinations, drive profound anti-tumor activity in preclinical mode... von Koltun, Elena, Cregg, Jim, Rice, Meghan A., Whalen, Dan M., Freilich, Rebecca, Jiang, Jingjing, Hansen, Richard, Bermingham, Alun, Knox, John E., Dinglasan, Jay, Seamon, Kyle, Blaj, Cristina, Chang, Stephanie S., Liu, Yang, Huang, Jun, Chou, Kang-Jye, McDowell, Laura, Lee, Bianca J., Wildes, David, Wang, Zhengping, Singh, Mallika, Gill, Adrian L., Smith, Jacqueline A.

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Quantitative proteomic profiling reveals key pathways in the anti-cancer action of methoxychalcone derivatives in triple negative breast cancer von Going, Catherine C., Tailor, Dhanir, Kumar, Vineet, Birk, Alisha M., Pandrala, Mallesh, Rice, Meghan A., Stoyanova, Tanya, Malhotra, Sanjay, Pitteri, Sharon J.

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Abstract 1467: The miR-23b/-27b cluster decreases metastasis of aggressive prostate cancer von Rice, Meghan A., Ishteiwy, Reema, Udayakumar, Thirupandiyur, Dykxhoorn, Derek, Burnstein, Kerry L.

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