INTERIM REPORT FROM A PHASE 2 MULTICENTER STUDY OF TAZEMETOSTAT, AN EZH2 INHIBITOR, IN PATIENTS WITH RELAPSED OR REFRACTORY B‐CELL NON‐HODGKIN LYMPHOMAS von Morschhauser, F., Salles, G., McKay, P., Tilly, H., Schmitt, A., Gerecitano, J., Johnson, P., Le Gouill, S., Dickinson, M.J., Fruchart, C., Lamy, T., Chaidos, A., Jurczak, W., Opat, S., Radford, J., Zinzani, P.L., Assouline, S., Cartron, G., Clawson, A., Picazio, N., Ribich, S., Blakemore, S.J., Larus, J., Miao, H., Ho, P.T., Ribrag, V.

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A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality von Grassian, A R, Scales, T M E, Knutson, S K, Kuntz, K W, McCarthy, N J, Lowe, C E, Moore, J D, Copeland, R A, Keilhack, H, Smith, J J, Wickenden, J A, Ribich, S

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Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations von McLean, P J, Kawamata, H, Ribich, S, Hyman, B T

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Characterization of IS1676 from Rhodococcus erythropolis SQ1 von Lessard, P.A, O'Brien, X.M, Ahlgren, N.A, Ribich, S.A, Sinskey, A.J

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Promoter Choice Determines Splice Site Selection in Protocadherin α and γ Pre-mRNA Splicing von Tasic, Bosiljka, Nabholz, Christoph E., Baldwin, Kristin K., Kim, Youngwook, Rueckert, Erroll H., Ribich, Scott A., Cramer, Paula, Wu, Qiang, Axel, Richard, Maniatis, Tom

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Characterization of IS 1676 from Rhodococcus erythropolis SQ1 von Lessard, P. A., O'Brien, X. M., Ahlgren, N. A., Ribich, S. A., Sinskey, A. J.

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Additional file 1: of A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality von A. Grassian, T. Scales, S. Knutson, K. Kuntz, N. McCarthy, C. Lowe, J. Moore, R. Copeland, H. Keilhack, J. Smith, J. Wickenden, S. Ribich

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Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models von Chan-Penebre, Elayne, Armstrong, Kelli, Drew, Allison, Grassian, Alexandra R, Feldman, Igor, Knutson, Sarah K, Kuplast-Barr, Kristy, Roche, Maria, Campbell, John, Ho, Peter, Copeland, Robert A, Chesworth, Richard, Smith, Jesse J, Keilhack, Heike, Ribich, Scott A

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ROTATING CUTTING TOOL von RIBICH T,US

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SE358575 von RIBICH T,US

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Drug Discovery and Chemical Biology of Cancer Epigenetics von Ribich, Scott, Harvey, Darren, Copeland, Robert A.

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EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL von Brach, Dorothy, Johnston-Blackwell, Danielle, Drew, Allison, Lingaraj, Trupti, Motwani, Vinny, Warholic, Natalie M, Feldman, Igor, Plescia, Christopher, Smith, Jesse J, Copeland, Robert A, Keilhack, Heike, Chan-Penebre, Elayne, Knutson, Sarah K, Ribich, Scott A, Raimondi, Alejandra, Thomenius, Michael J

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Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss von Fedoriw, Andrew, Rajapurkar, Satyajit R., O'Brien, Shane, Gerhart, Sarah V., Mitchell, Lorna H., Adams, Nicholas D., Rioux, Nathalie, Lingaraj, Trupti, Ribich, Scott A., Pappalardi, Melissa B., Shah, Niyant, Laraio, Jenny, Liu, Yan, Butticello, Michael, Carpenter, Chris L., Creasy, Caretha, Korenchuk, Susan, McCabe, Michael T., McHugh, Charles F., Nagarajan, Raman, Wagner, Craig, Zappacosta, Francesca, Annan, Roland, Concha, Nestor O., Thomas, Roberta A., Hart, Timothy K., Smith, Jesse J., Copeland, Robert A., Moyer, Mikel P., Campbell, John, Stickland, Kim, Mills, James, Jacques-O’Hagan, Suzanne, Allain, Christina, Johnston, Danielle, Raimondi, Alejandra, Porter Scott, Margaret, Waters, Nigel, Swinger, Kerren, Boriack-Sjodin, Ann, Riera, Tom, Shapiro, Gideon, Chesworth, Richard, Prinjha, Rabinder K., Kruger, Ryan G., Barbash, Olena, Mohammad, Helai P.

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RNA-modifying proteins as anticancer drug targets von Boriack-Sjodin, P. Ann, Ribich, Scott, Copeland, Robert A.

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A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models von Chan-Penebre, Elayne, Kuplast, Kristy G, Majer, Christina R, Boriack-Sjodin, P Ann, Wigle, Tim J, Johnston, L Danielle, Rioux, Nathalie, Munchhof, Michael J, Jin, Lei, Jacques, Suzanne L, West, Kip A, Lingaraj, Trupti, Stickland, Kimberly, Ribich, Scott A, Raimondi, Alejandra, Scott, Margaret Porter, Waters, Nigel J, Pollock, Roy M, Smith, Jesse J, Barbash, Olena, Pappalardi, Melissa, Ho, Thau F, Nurse, Kelvin, Oza, Khyati P, Gallagher, Kathleen T, Kruger, Ryan, Moyer, Mikel P, Copeland, Robert A, Chesworth, Richard, Duncan, Kenneth W

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Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma von Drew, Allison E., Moradei, Oscar, Jacques, Suzanne L., Rioux, Nathalie, Boriack-Sjodin, Ann P., Allain, Christina, Scott, Margaret Porter, Jin, Lei, Raimondi, Alejandra, Handler, Jessica L., Ott, Heidi M., Kruger, Ryan G., McCabe, Michael T., Sneeringer, Christopher, Riera, Thomas, Shapiro, Gideon, Waters, Nigel J., Mitchell, Lorna H., Duncan, Kenneth W., Moyer, Mikel P., Copeland, Robert A., Smith, Jesse, Chesworth, Richard, Ribich, Scott A.

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Tazemetostat, an EZH2 inhibitor, in relapsed or refractory B-cell non-Hodgkin lymphoma and advanced solid tumours: a first-in-human, open-label, phase 1 study von Italiano, Antoine, Soria, Jean-Charles, Toulmonde, Maud, Michot, Jean-Marie, Lucchesi, Carlo, Varga, Andrea, Coindre, Jean-Michel, Blakemore, Stephen J, Clawson, Alicia, Suttle, Benjamin, McDonald, Alice A, Woodruff, Mark, Ribich, Scott, Hedrick, Eric, Keilhack, Heike, Thomson, Blythe, Owa, Takashi, Copeland, Robert A, Ho, Peter T C, Ribrag, Vincent

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FASTENER von RUSSELL D,US, RIBICH W,US

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Identification of long-range regulatory elements in the protocadherin-α gene cluster von Ribich, Scott, Tasic, Bosiljka, Maniatis, Tom

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Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound von Mitchell, Lorna H., Drew, Allison E., Ribich, Scott A., Rioux, Nathalie, Swinger, Kerren K., Jacques, Suzanne L., Lingaraj, Trupti, Boriack-Sjodin, P. Ann, Waters, Nigel J., Wigle, Tim J., Moradei, Oscar, Jin, Lei, Riera, Tom, Porter-Scott, Margaret, Moyer, Mikel P., Smith, Jesse J., Chesworth, Richard, Copeland, Robert A.

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