Analysis of genetics and DNA methylation in osteoarthritis: What have we learnt about the disease? von Reynard, Louise N

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CpG methylation regulates allelic expression of GDF5 by modulating binding of SP1 and SP3 repressor proteins to the osteoarthritis susceptibility SNP rs143383 von Reynard, Louise N., Bui, Catherine, Syddall, Catherine M., Loughlin, John

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Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis von Rushton, Michael D., Reynard, Louise N., Barter, Matt J., Refaie, Ramsay, Rankin, Kenneth S., Young, David A., Loughlin, John

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Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP von Shepherd, Colin, Reese, Abigail E, Reynard, Louise N, Loughlin, John

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Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency von Dickinson, Rachel Emma, Griffin, Helen, Bigley, Venetia, Reynard, Louise N., Hussain, Rafiqul, Haniffa, Muzlifah, Lakey, Jeremy H., Rahman, Thahira, Wang, Xiao-Nong, McGovern, Naomi, Pagan, Sarah, Cookson, Sharon, McDonald, David, Chua, Ignatius, Wallis, Jonathan, Cant, Andrew, Wright, Michael, Keavney, Bernard, Chinnery, Patrick F., Loughlin, John, Hambleton, Sophie, Santibanez-Koref, Mauro, Collin, Matthew

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Functional Characterization of the Osteoarthritis Genetic Risk Residing at ALDH1A2 Identifies rs12915901 as a Key Target Variant von Shepherd, Colin, Zhu, Dongxing, Skelton, Andrew J., Combe, Jennifer, Threadgold, Harrison, Zhu, Linyi, Vincent, Tonia L., Stuart, Paul, Reynard, Louise N., Loughlin, John

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A Bayesian network approach incorporating imputation of missing data enables exploratory analysis of complex causal biological relationships von Howey, Richard, Clark, Alexander D., Naamane, Najib, Reynard, Louise N., Pratt, Arthur G., Cordell, Heather J.

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Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation von Reynard, Louise N., Bui, Catherine, Canty-Laird, Elizabeth G., Young, David A., Loughlin, John

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cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chond... von Bui, Catherine, Barter, Matt J., Scott, Jenny L., Xu, Yaobo, Galler, Martin, Reynard, Louise N., Rowan, Andrew D., Young, David A.

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The identification of trans-acting factors that regulate the expression of GDF5 via the osteoarthritis susceptibility SNP rs143383 von Syddall, Catherine M, Reynard, Louise N, Young, David A, Loughlin, John

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Correlation of Infinium HumanMethylation450K and MethylationEPIC BeadChip arrays in cartilage von Cheung, Kathleen, Burgers, Marjolein J., Young, David A., Cockell, Simon, Reynard, Louise N.

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A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF... von Ratnayake, Madhushika, Tselepi, Maria, Bloxham, Robert, Plöger, Frank, Reynard, Louise N, Loughlin, John

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Functional Characterization of the Osteoarthritis Susceptibility Mapping to CHST11-A Bioinformatics and Molecular Study von Reynard, Louise N, Ratnayake, Madhushika, Santibanez-Koref, Mauro, Loughlin, John

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Dual Proteolytic Pathways Govern Glycolysis and Immune Competence von Lu, Wei, Zhang, Yu, McDonald, David O., Jing, Huie, Carroll, Bernadette, Robertson, Nic, Zhang, Qian, Griffin, Helen, Sanderson, Sharon, Lakey, Jeremy H., Morgan, Neil V., Reynard, Louise N., Zheng, Lixin, Murdock, Heardley M., Turvey, Stuart E., Hackett, Scott J., Prestidge, Tim, Hall, Julie M., Cant, Andrew J., Matthews, Helen F., Koref, Mauro F. Santibanez, Simon, Anna Katharina, Korolchuk, Viktor I., Lenardo, Michael J., Hambleton, Sophie, Su, Helen C.

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Multi-Copy Mouse Gene Sycp3-Like Y-Linked (Sly) Encodes an Abundant Spermatid Protein That Interacts with a Histone Acetyltransferase and an Acrosomal Protein von Reynard, Louise N, Cocquet, Julie, Burgoyne, Paul S

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Genetics and epigenetics of osteoarthritis von Reynard, Louise N, Loughlin, John

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The genetics and functional analysis of primary osteoarthritis susceptibility von Reynard, Louise N., Loughlin, John

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Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci von Rice, Sarah J., Tselepi, Maria, Sorial, Antony K., Aubourg, Guillaume, Shepherd, Colin, Almarza, David, Skelton, Andrew J., Pangou, Ioanna, Deehan, David, Reynard, Louise N., Loughlin, John

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Histone ChIP‐Seq identifies differential enhancer usage during chondrogenesis as critical for defining cell‐type specificity von Cheung, Kathleen, Barter, Matthew J., Falk, Julia, Proctor, Carole J., Reynard, Louise N., Young, David A.

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Cryptic splicing: common pathological mechanisms involved in male infertility and neuronal diseases von Aldalaqan, Saad, Dalgliesh, Caroline, Luzzi, Sara, Siachisumo, Chileleko, Reynard, Louise N, Ehrmann, Ingrid, Elliott, David J.

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