Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive th... von Bai, Haiyan, Padron, Alvaro S, Deng, Yilun, Liao, Yiji J, Murray, Clare J, Ontiveros, Carlos, Kari, Suresh J, Kancharla, Aravind, Kornepati, Anand V R, Garcia, Myrna, Reyes, Ryan Michael, Gupta, Harshita B, Conejo-Garcia, Jose R, Curiel, Tyler

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CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation von Reyes, Ryan Michael, Deng, Yilun, Zhang, Deyi, Ji, Niannian, Mukherjee, Neelam, Wheeler, Karen, Gupta, Harshita B, Padron, Alvaro S, Kancharla, Aravind, Zhang, Chenghao, Garcia, Myrna, Kornepati, Anand V R, Boyman, Onur, Conejo-Garcia, Jose R, Svatek, Robert S, Curiel, Tyler J

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Selective IL-2 receptor β (CD122) targeting improves αPD-L1 immunotherapy in a metastatic bladder cancer model von Reyes, Ryan Michael, Zhang, Deyi, Deng, Yilun, Mukherjee, Neelam, Ji, Niannian, Gupta, Harshita B, Svatek, Robert S, Curiel, Tyler J

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CD122-selective IL-2 complexes target γδ T and NK cells to reduce tumor-promoting Th17 effects and synergize with αPD-L1 to treat primary and metastatic bladder cancer von Reyes, Ryan Michael, Deng, Yilun, Zhang, Deyi, Mukherjee, Neelam, Ji, Niannian, Wheeler, Karen, Gupta, Harshita B., Garcia, Myrna, Kornepati, Anand, Svatek, Robert S, Curiel, Tyler J

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CD122-selective IL-2 complexes treat ovarian carcinomas and melanoma, alter Treg differentiation and induce more CD8+CXCR5+TCF-1+ stem T cells when combined with αPD-L1 von Deng, Yilun, Gupta, Harshita B., Drerup, Justin Michael, Reyes, Ryan Michael, Mendez, Jenny, Zhang, Xinyue, Padron, Alvaro S, Garcia, Myrna, Curiel, Tyler J

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CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation von Reyes, Ryan Michael, Deng, Yilun, Zhang, Deyi, Ji, Niannian, Mukherjee, Neelam, Wheeler, Karen, Gupta, Harshita B, Padron, Alvaro S, Kancharla, Aravind, Zhang, Chenghao, Garcia, Myrna, Kornepati, Anand V R, Boyman, Onur, Conejo-Garcia, Jose R, Svatek, Robert S, Curiel, Tyler J

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Zika viruses of African and Asian lineages cause fetal harm in a mouse model of vertical transmission von Jaeger, Anna S, Murrieta, Reyes A, Goren, Lea R, Crooks, Chelsea M, Moriarty, Ryan V, Weiler, Andrea M, Rybarczyk, Sierra, Semler, Matthew R, Huffman, Christopher, Mejia, Andres, Simmons, Heather A, Fritsch, Michael, Osorio, Jorge E, Eickhoff, Jens C, O'Connor, Shelby L, Ebel, Gregory D, Friedrich, Thomas C, Aliota, Matthew T

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Co‐occurrence of California Drought and Northeast Pacific Marine Heatwaves Under Climate Change von Shi, Hui, García‐Reyes, Marisol, Jacox, Michael G., Rykaczewski, Ryan R., Black, Bryan A., Bograd, Steven J., Sydeman, William J.

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Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation von Lim, Ryan G., Al-Dalahmah, Osama, Wu, Jie, Gold, Maxwell P., Reidling, Jack C., Tang, Guomei, Adam, Miriam, Dansu, David K., Park, Hye-Jin, Casaccia, Patrizia, Miramontes, Ricardo, Reyes-Ortiz, Andrea M., Lau, Alice, Hickman, Richard A., Khan, Fatima, Paryani, Fahad, Tang, Alice, Ofori, Kenneth, Miyoshi, Emily, Michael, Neethu, McClure, Nicolette, Flowers, Xena E., Vonsattel, Jean Paul, Davidson, Shawn, Menon, Vilas, Swarup, Vivek, Fraenkel, Ernest, Goldman, James E., Thompson, Leslie M.

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Compositionally and density stratified igneous terrain in Jezero crater, Mars von Wiens, Roger C, Udry, Arya, Beyssac, Olivier, Quantin-Nataf, Cathy, Mangold, Nicolas, Cousin, Agnès, Mandon, Lucia, Bosak, Tanja, Forni, Olivier, McLennan, Scott M, Sautter, Violaine, Brown, Adrian, Benzerara, Karim, Johnson, Jeffrey R, Mayhew, Lisa, Maurice, Sylvestre, Anderson, Ryan B, Clegg, Samuel M, Crumpler, Larry, Gabriel, Travis S J, Gasda, Patrick, Hall, James, Horgan, Briony H N, Kah, Linda, Legett, 4th, Carey, Madariaga, Juan Manuel, Meslin, Pierre-Yves, Ollila, Ann M, Poulet, Francois, Royer, Clement, Sharma, Shiv K, Siljeström, Sandra, Simon, Justin I, Acosta-Maeda, Tayro E, Alvarez-Llamas, Cesar, Angel, S Michael, Arana, Gorka, Beck, Pierre, Bernard, Sylvain, Bertrand, Tanguy, Bousquet, Bruno, Castro, Kepa, Chide, Baptiste, Clavé, Elise, Cloutis, Ed, Connell, Stephanie, Dehouck, Erwin, Dromart, Gilles, Fischer, Woodward, Fouchet, Thierry, Francis, Raymond, Frydenvang, Jens, Gasnault, Olivier, Gibbons, Erin, Gupta, Sanjeev, Hausrath, Elisabeth M, Jacob, Xavier, Kalucha, Hemani, Kelly, Evan, Knutsen, Elise, Lanza, Nina, Laserna, Javier, Lasue, Jeremie, Le Mouélic, Stéphane, Leveille, Richard, Lopez Reyes, Guillermo, Lorenz, Ralph, Manrique, Jose Antonio, Martinez-Frias, Jesus, McConnochie, Tim, Melikechi, Noureddine, Mimoun, David, Montmessin, Franck, Moros, Javier, Murdoch, Naomi, Pilleri, Paolo, Pilorget, Cedric, Pinet, Patrick, Rapin, William, Rull, Fernando, Schröder, Susanne, Shuster, David L, Smith, Rebecca J, Stott, Alexander E, Tarnas, Jesse, Turenne, Nathalie, Veneranda, Marco, Vogt, David S, Weiss, Benjamin P, Willis, Peter, Stack, Kathryn M, Williford, Kenneth H, Farley, Kenneth A

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Histological Predictors of Outcome in Ependymoma are Dependent on Anatomic Site Within the Central Nervous System von Raghunathan, Aditya, Wani, Khalida, Armstrong, Terri S., Vera-Bolanos, Elizabeth, Fouladi, Maryam, Gilbertson, Richard, Gajjar, Amar, Goldman, Stewart, Lehman, Norman L., Metellus, Phillipe, Mikkelsen, Tom, Necesito-Reyes, Mary Jo T., Omuro, Antonio, Packer, Roger J., Partap, Sonia, Pollack, Ian F., Prados, Michael D., Robins, H. Ian, Soffietti, Riccardo, Wu, Jing, Miller, C. Ryan, Gilbert, Mark R., Aldape, Kenneth D.

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Overview of the Morphology and Chemistry of Diagenetic Features in the Clay‐Rich Glen Torridon Unit of Gale Crater, Mars von Gasda, Patrick J., Comellas, Jade, Essunfeld, Ari, Das, Debarati, Bryk, Alexander B., Dehouck, Erwin, Schwenzer, Susanne P., Crossey, Laura, Herkenhoff, Kenneth, Johnson, Jeffrey R., Newsom, Horton, Lanza, Nina L., Rapin, William, Goetz, Walter, Meslin, Pierre‐Yves, Bridges, John C., Anderson, Ryan, David, Gael, Turner, Stuart M. R., Thorpe, Michael T., Kah, Linda, Frydenvang, Jens, Kronyak, Rachel, Caravaca, Gwénaël, Ollila, Ann, Le Mouélic, Stéphane, Nellessen, Matthew, Hoffman, Megan, Fey, Deirdra, Cousin, Anges, Wiens, Roger C., Clegg, Samuel M., Maurice, Sylvestre, Gasnault, Olivier, Delapp, Dorothea, Reyes‐Newell, Adriana

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Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study von Wijeysundera, Duminda N, Shulman, Mark A, Croal, Bernard L, Granton, John T, Grocott, Michael P W, Farrington, Catherine, Wallace, Sophie, Thompson, Bruce, Ellis, Mathew, Borg, Brigette, Pretto, Jeff, Godsall, Guy, Beauchamp, Nicola, Allen, Sandra, Wright, Ewan, Malherbe, Johan, Sivakumar, Harry, Kenchington, Kay, Kirabiyik, Yesim, Gurunathan, Usha, Brunello, Kate, Steele, Katherine, Dent, Annette, Painter, Thomas W, Macklin, Simon, Carrera, Anna Maria, Pitt, Simon, Samuel, Joanne, Leslie, Kate, MacCormick, Andrew, Southcott, Anne Marie, Taylor, Hugh, Towns, Miriam, Tippett, Anna, Mazer, C David, Kunasingam, Janarthanee, Yagnik, Anmol, Crescini, Charmagne, Yagnik, Sanjay, McCartney, Colin JL, Somascanthan, Priya, Au, Shelly, Beattie, W Scott, McCluskey, Stuart A, Day, Lauren, Pazmino-Canizares, Janneth, Oh, Paul, Lee, Leanna, Brull, Richard, Ami, Noam, Stanbrook, Matthew, Hagen, Katherine, Short, Timothy, Van Der Westhuizen, Joreline, Higgie, Kushlin, Wong, Chris, Ali, Marlynn, Kim, Chang Joon, Dimech, Julian, Lorimer, Michael, Collingwood, Andrew, Olliff, Sue, Houston, Helen, Dalley, Paul, Andrews, Lynn, Jason-Smith, Adelaide, McMillan, Natalie, Lum, Mark, Martin, Daniel, James, Sarah, Pinto, Manuel, Beilstein, Christian, Bodger, Pheobe, Everingham, Kirsty, Hu, Ying, Creary, Thais, Ahmad, Tahania, Haslop, Richard, MacDonald, Neil, Greaves, Kathryn, Jhanji, Shaman, Lawrence, Helen, Koutra, Maria, Pirie, Katrina, Gertsman, Michelle, Jack, Sandy, Celinski, Michael, Edwards, Mark, Salmon, Karen, Bolger, Clare, Loughney, Lisa, Seaward, Leanne, Collins, Hannah, Tantony, Natasha, Stephens, RCM, Gallego-Paredes, Laura, Gutierrez del Arroyo, Ana, Melo, Magda, Mamdani, Muhammad, Wijeysundera, Harindra C

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Circulating Immune Cell and Outcome Analysis from the Phase II Study of PD-L1 Blockade with Durvalumab for Newly Diagnosed and Recurrent Glioblastoma von Nayak, Lakshmi, Standifer, Nathan, Dietrich, Jorg, Clarke, Jennifer L, Dunn, Gavin P, Lim, Michael, Cloughesy, Timothy, Gan, Hui K, Flagg, Elizabeth, George, Elizabeth, Gaffey, Sarah, Hayden, Julia, Holcroft, Christina, Wen, Patrick Y, Macri, Mary, Park, Andrew J, Ricciardi, Toni, Ryan, Aileen, Schwarzenberger, Paul, Venhaus, Ralph, Reyes, Melissa de Los, Durham, Nicholas M, Creasy, Todd, Huang, Raymond Y, Kaley, Thomas, Reardon, David A

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Future change of summer hypoxia in coastal California Current von Shi, Hui, Buil, Mercedes Pozo, Bograd, Steven J., García-Reyes, Marisol, Jacox, Michael G., Black, Bryan A., Sydeman, William J., Rykaczewski, Ryan R.

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Cardiac phenotype in ATP1A3-related syndromes: A multicenter cohort study von Balestrini, Simona, Mikati, Mohamad A., Álvarez-García-Rovés, Reyes, Carboni, Michael, Hunanyan, Arsen S., Kherallah, Bassil, McLean, Melissa, Prange, Lyndsey, De Grandis, Elisa, Gagliardi, Alessandra, Pisciotta, Livia, Stagnaro, Michela, Veneselli, Edvige, Campistol, Jaume, Fons, Carmen, Pias-Peleteiro, Leticia, Brashear, Allison, Miller, Charlotte, Samões, Raquel, Brankovic, Vesna, Padiath, Quasar S., Potic, Ana, Pilch, Jacek, Vezyroglou, Aikaterini, Bye, Ann M.E., Davis, Andrew M., Ryan, Monique M., Semsarian, Christopher, Hollingsworth, Georgina, Scheffer, Ingrid E., Granata, Tiziana, Nardocci, Nardo, Ragona, Francesca, Arzimanoglou, Alexis, Panagiotakaki, Eleni, Carrilho, Inês, Zucca, Claudio, Novy, Jan, Dzieżyc, Karolina, Parowicz, Marek, Mazurkiewicz-Bełdzińska, Maria, Weckhuysen, Sarah, Pons, Roser, Groppa, Sergiu, Sinden, Daniel S., Pitt, Geoffrey S., Tinker, Andrew, Ashworth, Michael, Michalak, Zuzanna, Thom, Maria, Cross, J. Helen, Vavassori, Rosaria, Kaski, Juan P., Sisodiya, Sanjay M.

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Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a phase 3b/4,... von Fleischmann, Roy, Prof, Mysler, Eduardo, MD, Hall, Stephen, MD, Kivitz, Alan J, MD, Moots, Robert J, Prof, Luo, Zhen, PhD, DeMasi, Ryan, MD, Soma, Koshika, MD, Zhang, Richard, PhD, Takiya, Liza, PharmD, Tatulych, Svitlana, MD, Mojcik, Christopher, MD, Krishnaswami, Sriram, PhD, Menon, Sujatha, PhD, Smolen, Josef S, Prof

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Affinity gaps among B cells in germinal centers drive the selection of MPER precursors von Ray, Rashmi, Schiffner, Torben, Wang, Xuesong, Yan, Yu, Rantalainen, Kimmo, Lee, Chang-Chun David, Parikh, Shivang, Reyes, Raphael A., Dale, Gordon A., Lin, Ying-Cing, Pecetta, Simone, Giguere, Sophie, Swanson, Olivia, Kratochvil, Sven, Melzi, Eleonora, Phung, Ivy, Madungwe, Lisa, Kalyuzhniy, Oleksandr, Warner, John, Weldon, Stephanie R., Tingle, Ryan, Lamperti, Edward, Kirsch, Kathrin H., Phelps, Nicole, Georgeson, Erik, Adachi, Yumiko, Kubitz, Michael, Nair, Usha, Crotty, Shane, Wilson, Ian A., Schief, William R., Batista, Facundo D.

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Global decline in ocean memory over the 21st century von Shi, Hui, Jin, Fei-Fei, Wills, Robert C J, Jacox, Michael G, Amaya, Dillon J, Black, Bryan A, Rykaczewski, Ryan R, Bograd, Steven J, García-Reyes, Marisol, Sydeman, William J

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Burmese python genome reveals the molecular basis for extreme adaptation in snakes von Castoe, Todd A., de Koning, A. P. Jason, Hall, Kathryn T., Card, Daren C., Schield, Drew R., Fujita, Matthew K., Ruggiero, Robert P., Degner, Jack F., Daza, Juan M., Gu, Wanjun, Reyes-Velasco, Jacobo, Shaney, Kyle J., Castoe, Jill M., Fox, Samuel E., Poole, Alex W., Polanco, Daniel, Dobry, Jason, Vandewege, Michael W., Li, Qing, Schott, Ryan K., Kapusta, Aurélie, Minx, Patrick, Feschotte, Cédric, Uetz, Peter, Ray, David A., Hoffmann, Federico G., Bogden, Robert, Smith, Eric N., Chang, Belinda S. W., Vonk, Freek J., Casewell, Nicholas R., Henkel, Christiaan V., Richardson, Michael K., Mackessy, Stephen P., Bronikowsi, Anne M., Yandell, Mark, Warren, Wesley C., Secor, Stephen M., Pollock, David D.

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