Cancer immunotherapy: moving beyond current vaccines von Rosenberg, Steven A, Yang, James C, Restifo, Nicholas P

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Natural selection of tumor variants in the generation of "tumor escape" phenotypes von Khong, Hung T, Restifo, Nicholas P

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Adoptive immunotherapy for cancer: building on success von Gattinoni, Luca, Restifo, Nicholas P, Powell, Daniel J, Rosenberg, Steven A

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Inhibition of TGF-β signaling in genetically engineered tumor antigen-reactive T cells significantly enhances tumor treatment efficacy von Zhang, L, Yu, Z, Muranski, P, Palmer, D C, Restifo, N P, Rosenberg, S A, Morgan, R A

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Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells von Gattinoni, Luca, Klebanoff, Christopher A, Palmer, Douglas C, Wrzesinski, Claudia, Kerstann, Keith, Yu, Zhiya, Finkelstein, Steven E, Theoret, Marc R, Rosenberg, Steven A, Restifo, Nicholas P

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Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy von Klebanoff, Christopher A., Khong, Hung T., Antony, Paul A., Palmer, Douglas C., Restifo, Nicholas P.

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Central Memory Self/Tumor-Reactive CD8+T Cells Confer Superior Antitumor Immunity Compared with Effector Memory T Cells von Klebanoff, Christopher A., Gattinoni, Luca, Torabi-Parizi, Parizad, Kerstann, Keith, Cardones, Adela R., Finkelstein, Steven E., Palmer, Douglas C., Antony, Paul A., Hwang, Sam T., Rosenberg, Steven A., Waldmann, Thomas A., Restifo, Nicholas P.

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Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells von Gattinoni, Luca, Finkelstein, Steven E, Klebanoff, Christopher A, Antony, Paul A, Palmer, Douglas C, Spiess, Paul J, Hwang, Leroy N, Yu, Zhiya, Wrzesinski, Claudia, Heimann, David M, Surh, Charles D, Rosenberg, Steven A, Restifo, Nicholas P

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Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic Melanoma von Dudley, Mark E., Wunderlich, John R., Yang, James C., Sherry, Richard M., Topalian, Suzanne L., Restifo, Nicholas P., Royal, Richard E., Kammula, Udai, White, Don E., Mavroukakis, Sharon A., Rogers, Linda J., Gracia, Gerald J., Jones, Stephanie A., Mangiameli, David P., Pelletier, Michelle M., Gea-Banacloche, Juan, Robinson, Michael R., Berman, David M., Filie, Armando C., Abati, Andrea, Rosenberg, Steven A.

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Autoimmunity Correlates With Tumor Regression in Patients With Metastatic Melanoma Treated With Anti–Cytotoxic T-Lymphocyte Antigen-4 von ATTIA, Peter, PHAN, Giao Q, RESTIFO, Nicholas P, HAWORTH, Leah R, LEVY, Catherine, MAVROUKAKIS, Sharon A, NICHOL, Geoff, YELLIN, Michael J, ROSENBERG, Steven A, MAKER, Ajay V, ROBINSON, Michael R, QUEZADO, Martha M, YANG, James C, SHERRY, Richard M, TOPALIAN, Suzanne L, KAMMULA, Udai S, ROYAL, Richard E

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Cancer Regression and Autoimmunity Induced by Cytotoxic T Lymphocyte-Associated Antigen 4 Blockade in Patients with Metastatic Melanoma von Phan, Giao Q., Yang, James C., Sherry, Richard M., Hwu, Patrick, Topalian, Suzanne L., Schwartzentruber, Douglas J., Restifo, Nicholas P., Haworth, Leah R., Seipp, Claudia A., Freezer, Linda J., Morton, Kathleen E., Mavroukakis, Sharon A., Duray, Paul H., Steinberg, Seth M., Allison, James P., Davis, Thomas A., Rosenberg, Steven A.

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Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognition von Yang, S, Cohen, C J, Peng, P D, Zhao, Y, Cassard, L, Yu, Z, Zheng, Z, Jones, S, Restifo, N P, Rosenberg, S A, Morgan, R A

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CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells von Antony, Paul A, Piccirillo, Ciriaco A, Akpinarli, Akgul, Finkelstein, Steven E, Speiss, Paul J, Surman, Deborah R, Palmer, Douglas C, Chan, Chi-Chao, Klebanoff, Christopher A, Overwijk, Willem W, Rosenberg, Steven A, Restifo, Nicholas P

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Classification of current anticancer immunotherapies von Galluzzi, Lorenzo, Vacchelli, Erika, Bravo-San Pedro, José-Manuel, Buqué, Aitziber, Senovilla, Laura, Baracco, Elisa Elena, Bloy, Norma, Castoldi, Francesca, Abastado, Jean-Pierre, Agostinis, Patrizia, Apte, Ron N., Aranda, Fernando, Ayyoub, Maha, Beckhove, Philipp, Blay, Jean-Yves, Bracci, Laura, Caignard, Anne, Castelli, Chiara, Cavallo, Federica, Celis, Estaban, Cerundolo, Vincenzo, Clayton, Aled, Colombo, Mario P., Coussens, Lisa, Dhodapkar, Madhav V., Eggermont, Alexander M., Fearon, Douglas T., Fridman, Wolf H., Fučíková, Jitka, Gabrilovich, Dmitry I., Galon, Jérôme, Garg, Abhishek, Ghiringhelli, François, Giaccone, Giuseppe, Gilboa, Eli, Gnjatic, Sacha, Hoos, Axel, Hosmalin, Anne, Jäger, Dirk, Kalinski, Pawel, Kärre, Klas, Kepp, Oliver, Kiessling, Rolf, Kirkwood, John M., Klein, Eva, Knuth, Alexander, Lewis, Claire E., Liblau, Roland, Lotze, Michael T., Lugli, Enrico, Mach, Jean-Pierre, Mattei, Fabrizio, Mavilio, Domenico, Melero, Ignacio, Melief, Cornelis J., Mittendorf, Elizabeth A., Moretta, Lorenzo, Odunsi, Adekunke, Okada, Hideho, Palucka, Anna Karolina, Peter, Marcus E., Pienta, Kenneth J., Porgador, Angel, Prendergast, George C., Rabinovich, Gabriel A., Restifo, Nicholas P., Rizvi, Naiyer, Sautès-Fridman, Catherine, Schreiber, Hans, Seliger, Barbara, Shiku, Hiroshi, Silva-Santos, Bruno, Smyth, Mark J., Speiser, Daniel E., Spisek, Radek, Srivastava, Pramod K., Talmadge, James E., Tartour, Eric, Van Der Burg, Sjoerd H., Van Den Eynde, Benoît J., Vile, Richard, Wagner, Hermann, Weber, Jeffrey S, Whiteside, Theresa L., Wolchok, Jedd D., Zitvogel, Laurence, Zou, Weiping, Kroemer, Guido

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Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function von Zeng, Rong, Spolski, Rosanne, Finkelstein, Steven E, Oh, SangKon, Kovanen, Panu E, Hinrichs, Christian S, Pise-Masison, Cynthia A, Radonovich, Michael F, Brady, John N, Restifo, Nicholas P, Berzofsky, Jay A, Leonard, Warren J

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Cancer Regression and Autoimmunity in Patients after Clonal Repopulation with Antitumor Lymphocytes von Dudley, Mark E., Wunderlich, John R., Robbins, Paul F., Yang, James C., Hwu, Patrick, Schwartzentruber, Douglas J., Topalian, Suzanne L., Sherry, Richard, Restifo, Nicholas P., Hubicki, Amy M., Robinson, Michael R., Raffeld, Mark, Duray, Paul, Seipp, Claudia A., Rogers-Freezer, Linda, Morton, Kathleen E., Mavroukakis, Sharon A., White, Donald E., Rosenberg, Steven A.

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Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape von Restifo, Nicholas P

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IL-15 Enhances the in vivo Antitumor Activity of Tumor-Reactive CD8+T Cells von Klebanoff, Christopher A., Finkelstein, Steven E., Surman, Deborah R., Lichtman, Michael K., Gattinoni, Luca, Theoret, Marc R., Grewal, Navrose, Spiess, Paul J., Antony, Paul A., Palmer, Douglas C., Tagaya, Yutaka, Rosenberg, Steven A., Waldmann, Thomas A., Restifo, Nicholas P.

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Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma von Rosenberg, Steven A, Sherry, Richard M, Morton, Kathleen E, Scharfman, William J, Yang, James C, Topalian, Suzanne L, Royal, Richard E, Kammula, Udai, Restifo, Nicholas P, Hughes, Marybeth S, Schwartzentruber, Douglas, Berman, David M, Schwarz, Susan L, Ngo, Lien T, Mavroukakis, Sharon A, White, Donald E, Steinberg, Seth M

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High Efficiency Transfection of Primary Human and Mouse T Lymphocytes Using RNA Electroporation von Zhao, Yangbing, Zheng, Zhili, Cohen, Cyrille J, Gattinoni, Luca, Palmer, Douglas C, Restifo, Nicholas P, Rosenberg, Steven A, Morgan, Richard A

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