Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy von Wang, Zhiyu, York, Nathaniel W., Nichols, Colin G., Remedi, Maria S.

Volltext

ATP-Sensitive Potassium Channels in Hyperinsulinism and Type 2 Diabetes: Inconvenient Paradox or New Paradigm? von Nichols, Colin G, York, Nathaniel W, Remedi, Maria S

Volltext

SGLT2 inhibitors therapy protects glucotoxicity-induced β-cell failure in a mouse model of human KATP-induced diabetes through mitigation of oxidative and ER stress von Shyr, Zeenat A, Yan, Zihan, Ustione, Alessandro, Egan, Erin M, Remedi, Maria S

Volltext

Loss of β-cell identity and dedifferentiation, not an irreversible process? von Patel, Sumit, Remedi, Maria S

Volltext

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression? von Nichols, Colin G., York, Nathaniel W., Remedi, Maria S.

Volltext

Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity von McClenaghan, Conor, Huang, Yan, Yan, Zihan, Harter, Theresa M, Halabi, Carmen M, Chalk, Rod, Kovacs, Attila, van Haaften, Gijs, Remedi, Maria S, Nichols, Colin G

Volltext

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion von Vigueira, Patrick A., McCommis, Kyle S., Schweitzer, George G., Remedi, Maria S., Chambers, Kari T., Fu, Xiaorong, McDonald, William G., Cole, Serena L., Colca, Jerry R., Kletzien, Rolf F., Burgess, Shawn C., Finck, Brian N.

Volltext

ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9 von Smeland, Marie F., McClenaghan, Conor, Roessler, Helen I., Savelberg, Sanne, Hansen, Geir Åsmund Myge, Hjellnes, Helene, Arntzen, Kjell Arne, Müller, Kai Ivar, Dybesland, Andreas Rosenberger, Harter, Theresa, Sala-Rabanal, Monica, Emfinger, Chris H., Huang, Yan, Singareddy, Soma S., Gunn, Jamie, Wozniak, David F., Kovacs, Attila, Massink, Maarten, Tessadori, Federico, Kamel, Sarah M., Bakkers, Jeroen, Remedi, Maria S., Van Ghelue, Marijke, Nichols, Colin G., van Haaften, Gijs

Volltext

Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the KATP channel von Remedi, Maria S, Friedman, Jonathan B, Nichols, Colin G

Volltext

A Unique High-Output Cardiac Hypertrophy Phenotype Arising From Low Systemic Vascular Resistance in Cantu Syndrome von Singh, Gautam K, McClenaghan, Conor, Aggarwal, Manish, Gu, Hongjie, Remedi, Maria S, Grange, Dorothy K, Nichols, Colin G

Volltext

Intermittent fasting protects β-cell identity and function in a type-2 diabetes model von Patel, Sumit, Yan, Zihan, Remedi, Maria S.

Volltext

1354-P: Alternate-Day Intermittent Fasting Improves Diabetes and Protects Beta-Cell Function in Polygenic Mouse Models of T2DM von PATEL, SUMIT, YAN, ZIHAN, REMEDI, MARIA S.

Volltext

Glucokinase Inhibition: A Novel Treatment for Diabetes? von Remedi, Maria S, Nichols, Colin G

Volltext

Glycogen Synthase Kinase-3 and Mammalian Target of Rapamycin Pathways Contribute to DNA Synthesis, Cell Cycle Progression, and Proliferation in Human Islets von Liu, Hui, Remedi, Maria S, Pappan, Kirk L, Kwon, Guim, Rohatgi, Nidhi, Marshall, Connie A, McDaniel, Michael L

Volltext

Signaling Elements Involved in the Metabolic Regulation of mTOR by Nutrients, Incretins, and Growth Factors in Islets von KWON, Guim, MARSHALL, Connie A, PAPPAN, Kirk L, REMEDI, Maria S, MCDANIEL, Michael L

Volltext

Should I Stay or Should I Go: A Clash of α-Cell Identity von Remedi, Maria S.

Volltext

An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion von McCommis, Kyle S, Hodges, Wesley T, Bricker, Daniel K, Wisidagama, Dona R, Compan, Vincent, Remedi, Maria S, Thummel, Carl S, Finck, Brian N

Volltext

Critical role of gap junction coupled KATP channel activity for regulated insulin secretion von Rocheleau, Jonathan V, Remedi, Maria S, Granada, Butch, Head, W Steven, Koster, Joseph C, Nichols, Colin G, Piston, David W

Volltext

43-OR: Islet Autophagic Flux Is Impaired Prior to the Onset of Type 1 Diabetes von CLARK, AMY L., YAN, ZIHAN, REMEDI, MARIA S., DIWAN, ABHINAV

Volltext

KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer's disease-related pathology von Grizzanti, John, Moritz, William R, Pait, Morgan C, Stanley, Molly, Kaye, Sarah D, Carroll, Caitlin M, Constantino, Nicholas J, Deitelzweig, Lily J, Snipes, James A, Kellar, Derek, Caesar, Emily E, Pettit-Mee, Ryan J, Day, Stephen M, Sens, Jonathon P, Nicol, Noelle I, Dhillon, Jasmeen, Remedi, Maria S, Kiraly, Drew D, Karch, Celeste M, Nichols, Colin G, Holtzman, David M, Macauley, Shannon L

Volltext