Synthetic lethal metabolic targeting of cellular senescence in cancer therapy von Dörr, Jan R., Yu, Yong, Milanovic, Maja, Beuster, Gregor, Zasada, Christin, Däbritz, J. Henry M., Lisec, Jan, Lenze, Dido, Gerhardt, Anne, Schleicher, Katharina, Kratzat, Susanne, Purfürst, Bettina, Walenta, Stefan, Mueller-Klieser, Wolfgang, Gräler, Markus, Hummel, Michael, Keller, Ulrich, Buck, Andreas K., Dörken, Bernd, Willmitzer, Lothar, Reimann, Maurice, Kempa, Stefan, Lee, Soyoung, Schmitt, Clemens A.

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma von Yu, Yong, Schleich, Kolja, Yue, Bin, Ji, Sujuan, Lohneis, Philipp, Kemper, Kristel, Silvis, Mark R., Qutob, Nouar, van Rooijen, Ellen, Werner-Klein, Melanie, Li, Lianjie, Dhawan, Dhriti, Meierjohann, Svenja, Reimann, Maurice, Elkahloun, Abdel, Treitschke, Steffi, Dörken, Bernd, Speck, Christian, Mallette, Frédérick A., Zon, Leonard I., Holmen, Sheri L., Peeper, Daniel S., Samuels, Yardena, Schmitt, Clemens A., Lee, Soyoung

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H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients von Schleich, Kolja, Kase, Julia, Dörr, Jan R., Trescher, Saskia, Bhattacharya, Animesh, Yu, Yong, Wailes, Elizabeth M., Fan, Dorothy N. Y., Lohneis, Philipp, Milanovic, Maja, Lau, Andrea, Lenze, Dido, Hummel, Michael, Chapuy, Bjoern, Leser, Ulf, Reimann, Maurice, Lee, Soyoung, Schmitt, Clemens A.

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The Myc/macrophage tango: Oncogene-induced senescence, Myc style von Lee, Soyoung, Schmitt, Clemens A, Reimann, Maurice

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Cellular senescence: Neither irreversible nor reversible von Reimann, Maurice, Lee, Soyoung, Schmitt, Clemens A

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The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo von Reimann, Maurice, Loddenkemper, Christoph, Rudolph, Cornelia, Schildhauer, Ines, Teichmann, Bianca, Stein, Harald, Schlegelberger, Brigitte, Dörken, Bernd, Schmitt, Clemens A.

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B-cell–specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice von Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Seeger, Jens M., Al-Baldawi, Yussor, Al-Maarri, Mona, Fritz, Christian, Vlantis, Katerina, Bezhanova, Svetlana, Scheel, Andreas H., Wolz, Olaf-Oliver, Reimann, Maurice, Möller, Peter, López, Cristina, Schlesner, Matthias, Lohneis, Philipp, Weber, Alexander N.R., Trümper, Lorenz, Staudt, Louis M., Ortmann, Monika, Pasparakis, Manolis, Siebert, Reiner, Schmitt, Clemens A., Klatt, Andreas R., Wunderlich, F.Thomas, Schäfer, Stephan C., Persigehl, Thorsten, Montesinos-Rongen, Manuel, Odenthal, Margarete, Büttner, Reinhard, Frenzel, Lukas P., Kashkar, Hamid, Reinhardt, H.Christian

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Virus-induced senescence is a driver and therapeutic target in COVID-19 von Lee, Soyoung, Yu, Yong, Trimpert, Jakob, Benthani, Fahad, Mairhofer, Mario, Richter-Pechanska, Paulina, Wyler, Emanuel, Belenki, Dimitri, Kaltenbrunner, Sabine, Pammer, Maria, Kausche, Lea, Firsching, Theresa C., Dietert, Kristina, Schotsaert, Michael, Martínez-Romero, Carles, Singh, Gagandeep, Kunz, Séverine, Niemeyer, Daniela, Ghanem, Riad, Salzer, Helmut J. F., Paar, Christian, Mülleder, Michael, Uccellini, Melissa, Michaelis, Edward G., Khan, Amjad, Lau, Andrea, Schönlein, Martin, Habringer, Anna, Tomasits, Josef, Adler, Julia M., Kimeswenger, Susanne, Gruber, Achim D., Hoetzenecker, Wolfram, Steinkellner, Herta, Purfürst, Bettina, Motz, Reinhard, Di Pierro, Francesco, Lamprecht, Bernd, Osterrieder, Nikolaus, Landthaler, Markus, Drosten, Christian, García-Sastre, Adolfo, Langer, Rupert, Ralser, Markus, Eils, Roland, Reimann, Maurice, Fan, Dorothy N. Y., Schmitt, Clemens A.

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Senescence-associated reprogramming promotes cancer stemness von Milanovic, Maja, Fan, Dorothy N. Y., Belenki, Dimitri, Däbritz, J. Henry M., Zhao, Zhen, Yu, Yong, Dörr, Jan R., Dimitrova, Lora, Lenze, Dido, Monteiro Barbosa, Ines A., Mendoza-Parra, Marco A., Kanashova, Tamara, Metzner, Marlen, Pardon, Katharina, Reimann, Maurice, Trumpp, Andreas, Dörken, Bernd, Zuber, Johannes, Gronemeyer, Hinrich, Hummel, Michael, Dittmar, Gunnar, Lee, Soyoung, Schmitt, Clemens A.

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Specific Interaction of p53 with Target Binding Sites Is Determined by DNA Conformation and Is Regulated by the C-terminal Domain von Göhler, Thomas, Reimann, Maurice, Cherny, Dimitry, Walter, Korden, Warnecke, Gabriele, Kim, Ella, Deppert, Wolfgang

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Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas von Reimann, Maurice, Schrezenmeier, Jens, Richter-Pechanska, Paulina, Dolnik, Anna, Hick, Timon Pablo, Schleich, Kolja, Cai, Xiurong, Fan, Dorothy N.Y., Lohneis, Philipp, Maßwig, Sven, Denker, Sophy, Busse, Antonia, Knittel, Gero, Flümann, Ruth, Childs, Dorothee, Childs, Liam, Gätjens-Sanchez, Ana-Maria, Bullinger, Lars, Rosenwald, Andreas, Reinhardt, Hans Christian, Schmitt, Clemens A.

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Tumor Stroma-Derived TGF-β Limits Myc-Driven Lymphomagenesis via Suv39h1-Dependent Senescence von Reimann, Maurice, Lee, Soyoung, Loddenkemper, Christoph, Dörr, Jan R., Tabor, Vedrana, Aichele, Peter, Stein, Harald, Dörken, Bernd, Jenuwein, Thomas, Schmitt, Clemens A.

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DLBCL-Derived NF-κb Mutations Exploit Senescence and Immune Evasion Mechanisms to Promote Myc-Driven Lymphomagenesis von Schrezenmeier, Jens F., Reimann, Maurice, Masswig, Sven, Childs, Liam, Childs, Dorothee, Lohneis, Philipp, Schmitt, Clemens A.

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Author Correction: Virus-induced senescence is a driver and therapeutic target in COVID-19 von Lee, Soyoung, Yu, Yong, Trimpert, Jakob, Benthani, Fahad, Mairhofer, Mario, Richter-Pechanska, Paulina, Wyler, Emanuel, Belenki, Dimitri, Kaltenbrunner, Sabine, Pammer, Maria, Kausche, Lea, Firsching, Theresa C, Dietert, Kristina, Schotsaert, Michael, Martínez-Romero, Carles, Singh, Gagandeep, Kunz, Séverine, Niemeyer, Daniela, Ghanem, Riad, Salzer, Helmut J F, Paar, Christian, Mülleder, Michael, Uccellini, Melissa, Michaelis, Edward G, Khan, Amjad, Lau, Andrea, Schönlein, Martin, Habringer, Anna, Tomasits, Josef, Adler, Julia M, Kimeswenger, Susanne, Gruber, Achim D, Hoetzenecker, Wolfram, Steinkellner, Herta, Purfürst, Bettina, Motz, Reinhard, Di Pierro, Francesco, Lamprecht, Bernd, Osterrieder, Nikolaus, Landthaler, Markus, Drosten, Christian, García-Sastre, Adolfo, Langer, Rupert, Ralser, Markus, Eils, Roland, Reimann, Maurice, Fan, Dorothy N Y, Schmitt, Clemens A

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma von Yu, Yong, Schleich, Kolja, Yue, Bin, Ji, Sujuan, Lohneis, Philipp, Kemper, Kristel, Silvis, Mark R., Qutob, Nouar, van Rooijen, Ellen, Werner-Klein, Melanie, Li, Lianjie, Dhawan, Dhriti, Meierjohann, Svenja, Reimann, Maurice, Elkahloun, Abdel, Treitschke, Steffi, Dörken, Bernd, Speck, Christian, Mallette, Frédérick A., Zon, Leonard I., Holmen, Sheri L., Peeper, Daniel S., Samuels, Yardena, Schmitt, Clemens A., Lee, Soyoung

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An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities von Flümann, Ruth, Rehkämper, Tim, Nieper, Pascal, Pfeiffer, Pauline, Holzem, Alessandra, Klein, Sebastian, Bhatia, Sanil, Kochanek, Moritz, Kisis, Ilmars, Pelzer, Benedikt W, Ahlert, Heinz, Hauer, Julia, da Palma Guerreiro, Alexandra, Ryan, Jeremy A, Reimann, Maurice, Riabinska, Arina, Wiederstein, Janica, Krüger, Marcus, Deckert, Martina, Altmüller, Janine, Klatt, Andreas R, Frenzel, Lukas P, Pasqualucci, Laura, Béguelin, Wendy, Melnick, Ari M, Sander, Sandrine, Montesinos-Rongen, Manuel, Brunn, Anna, Lohneis, Philipp, Büttner, Reinhard, Kashkar, Hamid, Borkhardt, Arndt, Letai, Anthony, Persigehl, Thorsten, Peifer, Martin, Schmitt, Clemens A, Reinhardt, Hans Christian, Knittel, Gero

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Opposing roles of NF-κB in anti-cancer treatment outcome unveiled by cross-species investigations von Jing, Hua, Kase, Julia, Dörr, Jan R, Milanovic, Maja, Lenze, Dido, Grau, Michael, Beuster, Gregor, Ji, Sujuan, Reimann, Maurice, Lenz, Peter, Hummel, Michael, Dörken, Bernd, Lenz, Georg, Scheidereit, Claus, Schmitt, Clemens A, Lee, Soyoung

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Modeling the CNS Tropism of Diffuse Large B-Cell Lymphomas in Vivo von Reimann, Maurice, Masswig, Sven, Schleich, Kolja, Herrmann, Andrea, Lohneis, Philipp, Schrezenmeier, Jens, Dörken, Bernd, Schmitt, Clemens

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Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma von Du, Jing, Neuenschwander, Martin, Yu, Yong, Däbritz, J.Henry M., Neuendorff, Nina-Rosa, Schleich, Kolja, Bittner, Aitomi, Milanovic, Maja, Beuster, Gregor, Radetzki, Silke, Specker, Edgar, Reimann, Maurice, Rosenbauer, Frank, Mathas, Stephan, Lohneis, Philipp, Hummel, Michael, Dörken, Bernd, von Kries, Jens Peter, Lee, Soyoung, Schmitt, Clemens A.

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Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas von Shortt, Jake, Martin, Benjamin P., Newbold, Andrea, Hannan, Katherine M., Devlin, Jennifer R., Baker, Adele J., Ralli, Rachael, Cullinane, Carleen, Schmitt, Clemens A., Reimann, Maurice, Hall, Michael N., Wall, Meaghan, Hannan, Ross D., Pearson, Richard B., McArthur, Grant A., Johnstone, Ricky W.

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