PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective von Cooper, Lee AD, Demicco, Elizabeth G, Saltz, Joel H, Powell, Reid T, Rao, Arvind, Lazar, Alexander J

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ATM functions at the peroxisome to induce pexophagy in response to ROS von Zhang, Jiangwei, Tripathi, Durga Nand, Jing, Ji, Alexander, Angela, Kim, Jinhee, Powell, Reid T., Dere, Ruhee, Tait-Mulder, Jacqueline, Lee, Ji-Hoon, Paull, Tanya T., Pandita, Raj K., Charaka, Vijaya K., Pandita, Tej K., Kastan, Michael B., Walker, Cheryl Lyn

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Dual Chromatin and Cytoskeletal Remodeling by SETD2 von Park, In Young, Powell, Reid T., Tripathi, Durga Nand, Dere, Ruhee, Ho, Thai H., Blasius, T. Lynne, Chiang, Yun-Chen, Davis, Ian J., Fahey, Catherine C., Hacker, Kathryn E., Verhey, Kristen J., Bedford, Mark T., Jonasch, Eric, Rathmell, W. Kimryn, Walker, Cheryl Lyn

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Molecular pathways enhance drug response prediction using transfer learning from cell lines to tumors and patient-derived xenografts von Tang, Yi-Ching, Powell, Reid T., Gottlieb, Assaf

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Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition von Zhao, Na, Powell, Reid T., Yuan, Xueying, Bae, Goeun, Roarty, Kevin P., Stossi, Fabio, Strempfl, Martina, Toneff, Michael J., Johnson, Hannah L., Mani, Sendurai A., Jones, Philip, Stephan, Clifford C., Rosen, Jeffrey M.

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Combination of EphA2- and Wee1-Targeted Therapies in Endometrial Cancer von Dasari, Santosh K, Joseph, Robiya, Umamaheswaran, Sujanitha, Mangala, Lingegowda S, Bayraktar, Emine, Rodriguez-Aguayo, Cristian, Wu, Yutuan, Nguyen, Nghi, Powell, Reid T, Sobieski, Mary, Liu, Yuan, Chowdhury, Mamur A, Amero, Paola, Stephan, Clifford, Lopez-Berestein, Gabriel, Westin, Shannon N, Sood, Anil K

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Cystic fibrosis cell models for high-throughput analysis and drug screening von Liu, Aidi, Chokshi, Mithil, Nguyen, Nghi, Powell, Reid T., Stephan, Clifford C., Bao, Gang

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A transgenic mouse model of Down syndrome acute lymphoblastic leukemia identifies targetable vulnerabilities von Junco, Jacob J, Rochette, Max, Alozie, Michelle, Rashid, Raushan, Terrell, Maci, Zorman, Barry, Sumazin, Pavel, Rowland, Lauren, Dettorre, Gino, Powell, Reid T, Stephan, Clifford C, Davies, Peter J, Martinez-Moczygemba, Margarita, Yang, Jun J, Rabin, Karen R

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Chemically targeting the redox switch in AP1 transcription factor ΔFOSB von Kumar, Ashwani, Aglyamova, Galina, Yim, Yun Young, Bailey, Aaron O, Lynch, Haley M, Powell, Reid T, Nguyen, Nghi D, Rosenthal, Zachary, Zhao, Wen-Ning, Li, Yi, Chen, Jianping, Fan, Shanghua, Lee, Hubert, Russell, William K, Stephan, Clifford, Robison, Alfred J, Haggarty, Stephen J, Nestler, Eric J, Zhou, Jia, Machius, Mischa, Rudenko, Gabby

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The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells von Puli, Oorvashi Roy, Danysh, Brian P, McBeath, Elena, Sinha, Deepankar K, Hoang, Nguyet M, Powell, Reid T, Danysh, Heather E, Cabanillas, Maria E, Cote, Gilbert J, Hofmann, Marie-Claude

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Combined TRIP13 and Aurora Kinase Inhibition Induces Apoptosis in Human Papillomavirus-Driven Cancers von Ghosh, Soma, Mazumdar, Tuhina, Xu, Wei, Powell, Reid T, Stephan, Clifford, Shen, Li, Shah, Pooja A, Pickering, Curtis R, Myers, Jeffery N, Wang, Jing, Frederick, Mitchell J, Johnson, Faye M

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SETD2 Haploinsufficiency for Microtubule Methylation Is an Early Driver of Genomic Instability in Renal Cell Carcinoma von Chiang, Yun-Chen, Park, In-Young, Terzo, Esteban A, Tripathi, Durga Nand, Mason, Frank M, Fahey, Catherine C, Karki, Menuka, Shuster, Charles B, Sohn, Bo-Hwa, Chowdhury, Pratim, Powell, Reid T, Ohi, Ryoma, Tsai, Yihsuan S, de Cubas, Aguirre A, Khan, Abid, Davis, Ian J, Strahl, Brian D, Parker, Joel S, Dere, Ruhee, Walker, Cheryl L, Rathmell, W Kimryn

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Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo von Fan, Fan, Ghosh, Susmita, Powell, Reid, Roszik, Jason, Park, Yongsun, Sobieski, Mary, Sorokin, Alexey, Stephan, Clifford, Kopetz, Scott, Ellis, Lee M, Bhattacharya, Rajat

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Vincristine Enhances the Efficacy of MEK Inhibitors in Preclinical Models of KRAS-mutant Colorectal Cancer von Ghosh, Susmita, Fan, Fan, Powell, Reid T, Roszik, Jason, Park, Yong Sung, Stephan, Clifford, Sebastian, Manu, Tan, Lin, Sorokin, Alexey V, Lorenzi, Philip L, Kopetz, Scott, Ellis, Lee M, Bhattacharya, Rajat

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EphA2- and HDAC-Targeted Combination Therapy in Endometrial Cancer von Joseph, Robiya, Dasari, Santosh K, Umamaheswaran, Sujanitha, Mangala, Lingegowda S, Bayraktar, Emine, Rodriguez-Aguayo, Cristian, Wu, Yutuan, Nguyen, Nghi, Powell, Reid T, Sobieski, Mary, Liu, Yuan, Kim, Mark Seungwook, Corvigno, Sara, Foster, Katherine, Hanjra, Pahul, Vu, Thanh Chung, Chowdhury, Mamur A, Amero, Paola, Stephan, Clifford, Lopez-Berestein, Gabriel, Westin, Shannon N, Sood, Anil K

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Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells von Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee

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Epichaperome inhibition targets TP53-mutant AML and AML stem/progenitor cells von Carter, Bing Z., Mak, Po Yee, Muftuoglu, Muharrem, Tao, Wenjing, Ke, Baozhen, Pei, Jingqi, Bedoy, Andrea D., Ostermann, Lauren B., Nishida, Yuki, Isgandarova, Sevinj, Sobieski, Mary, Nguyen, Nghi, Powell, Reid T., Martinez-Moczygemba, Margarita, Stephan, Clifford, Basyal, Mahesh, Pemmaraju, Naveen, Boettcher, Steffen, Ebert, Benjamin L., Shpall, Elizabeth J., Wallner, Barbara, Morgan, Robert A., Karras, Georgios I., Moll, Ute M., Andreeff, Michael

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Author Correction: Therapeutically actionable signaling node to rescue AURKA driven loss of primary cilia in VHL-deficient cells von Chowdhury, Pratim, Perera, Dimuthu, Powell, Reid T., Talley, Tia, Tripathi, Durga Nand, Park, Yong Sung, Mancini, Michael A., Davies, Peter, Stephan, Clifford, Coarfa, Cristian, Dere, Ruhee

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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na+ channel complex von Wadsworth, Paul A., Folorunso, Oluwarotimi, Nguyen, Nghi, Singh, Aditya K., D’Amico, Daniela, Powell, Reid T., Brunell, David, Allen, John, Stephan, Clifford, Laezza, Fernanda

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Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models von Handley, Katelyn F, Rodriguez-Aguayo, Cristian, Ma, Shaolin, Stur, Elaine, Joseph, Robiya, Bayraktar, Emine, Dasari, Santosh K, Nguyen, Nghi, Powell, Reid T, Sobieski, Mary, Ivan, Cristina, Kim, Mark, Umamaheswaran, Sujanitha, Glassman, Deanna, Wen, Yunfei, Amero, Paola, Stephan, Clifford, Coleman, Robert L, Landesman, Yosef, Westin, Shannon N, Ram, Prahlad T, Sood, Anil K

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