The metabolism of primaquine to its active metabolite is dependent on CYP 2D6 von Pybus, Brandon S, Marcsisin, Sean R, Jin, Xiannu, Deye, Gregory, Sousa, Jason C, Li, Qigui, Caridha, Diana, Zeng, Qiang, Reichard, Gregory A, Ockenhouse, Christian, Bennett, Jason, Walker, Larry A, Ohrt, Colin, Melendez, Victor

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CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine von Pybus, Brandon S, Sousa, Jason C, Jin, Xiannu, Ferguson, James A, Christian, Robert E, Barnhart, Rebecca, Vuong, Chau, Sciotti, Richard J, Reichard, Gregory A, Kozar, Michael P, Walker, Larry A, Ohrt, Colin, Melendez, Victor

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Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art von Marcsisin, Sean R, Reichard, Gregory, Pybus, Brandon S

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Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds von Marcsisin, Sean R, Sousa, Jason C, Reichard, Gregory A, Caridha, Diana, Zeng, Qiang, Roncal, Norma, McNulty, Ronan, Careagabarja, Julio, Sciotti, Richard J, Bennett, Jason W, Zottig, Victor E, Deye, Gregory, Li, Qigui, Read, Lisa, Hickman, Mark, Dhammika Nanayakkara, N P, Walker, Larry A, Smith, Bryan, Melendez, Victor, Pybus, Brandon S

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Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques von Vanachayangkul, Pattaraporn, Im-erbsin, Rawiwan, Tungtaeng, Anchalee, Kodchakorn, Chanikarn, Roth, Alison, Adams, John, Chaisatit, Chaiyaporn, Saingam, Piyaporn, Sciotti, Richard J, Reichard, Gregory A, Nolan, Christina K, Pybus, Brandon S, Black, Chad C, Lugo-Roman, Luis A, Wegner, Matthew D, Smith, Philip L, Wojnarski, Mariusz, Vesely, Brian A, Kobylinski, Kevin C

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Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population von Spring, Michele D., Sousa, Jason C., Li, Qigui, Darko, Christian A., Morrison, Meshell N., Marcsisin, Sean R., Mills, Kristin T., Potter, Brittney M., Paolino, Kristopher M., Twomey, Patrick S., Moon, James E., Tosh, Donna M., Cicatelli, Susan B., Froude, Jeffrey W., Pybus, Brandon S., Oliver, Thomas G., McCarthy, William F., Waters, Norman C., Smith, Philip L., Reichard, Gregory A., Bennett, Jason W.

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Development of an ectopic huLiver model for Plasmodium liver stage infection von Samayoa-Reyes, Gabriela, Flaherty, Siobhan M, Wickham, Kristina S, Viera-Morilla, Sara, Strauch, Pamela M, Roth, Alison, Padrón, Laura, Jackson, Conner M, Meireles, Patricia, Calvo, David, Roobsoong, Wanlapa, Kangwanrangsan, Niwat, Sattabongkot, Jetsumon, Reichard, Gregory, Lafuente-Monasterio, Maria José, Rochford, Rosemary

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Enantioselective metabolism of primaquine by human CYP2D6 von Fasinu, Pius S, Tekwani, Babu L, Nanayakkara, N P Dhammika, Avula, Bharathi, Herath, H M T Bandara, Wang, Yan-Hong, Adelli, Vijender R, Elsohly, Mahmoud A, Khan, Shabana I, Khan, Ikhlas A, Pybus, Brandon S, Marcsisin, Sean R, Reichard, Gregory A, McChesney, James D, Walker, Larry A

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Differential cytochrome P450 2D metabolism alters tafenoquine pharmacokinetics von Vuong, Chau, Xie, Lisa H, Potter, Brittney M J, Zhang, Jing, Zhang, Ping, Duan, Dehui, Nolan, Christina K, Sciotti, Richard J, Zottig, Victor E, Nanayakkara, N P Dhammika, Tekwani, Babu L, Walker, Larry A, Smith, Philip L, Paris, Robert M, Read, Lisa T, Li, Qigui, Pybus, Brandon S, Sousa, Jason C, Reichard, Gregory A, Smith, Bryan, Marcsisin, Sean R

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Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes von Fasinu, Pius S, Avula, Bharathi, Tekwani, Babu L, Nanayakkara, N P Dhammika, Wang, Yan-Hong, Bandara Herath, H M T, McChesney, James D, Reichard, Gregory A, Marcsisin, Sean R, Elsohly, Mahmoud A, Khan, Shabana I, Khan, Ikhlas A, Walker, Larry A

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Single-Dose Primaquine in a Preclinical Model of Glucose-6-Phosphate Dehydrogenase Deficiency: Implications for Use in Malaria Transmission-Blocking Programs von Wickham, Kristina S, Baresel, Paul C, Marcsisin, Sean R, Sousa, Jason, Vuong, Chau T, Reichard, Gregory A, Campo, Brice, Tekwani, Babu L, Walker, Larry A, Rochford, Rosemary

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Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles of Primaquine Enantiomers von DHAMMIKA NANAYAKKARA, N. P, TEKWANI, Babu L, FRONCZEK, Frank R, MELENDEZ, Victor, OHRT, Colin, REICHARD, Gregory A, MCCHESNEY, James D, ROCHFORD, Rosemary, WALKER, Larry A, BANDARA HERATH, H. M. T, SAHU, Rajnish, GETTAYACAMIN, Montip, TUNGTAENG, Anchalee, VAN GESSEL, Yvonne, BARESEL, Paul, WICKHAM, Kristina S, BARTLETT, Marilyn S

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CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever von Marcsisin, Sean R, Jin, Xiannu, Bettger, Theresa, McCulley, Nicholas, Sousa, Jason C, Shanks, G Dennis, Tekwani, Babu L, Sahu, Rajnish, Reichard, Gregory A, Sciotti, Richard J, Melendez, Victor, Pybus, Brandon S

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Updating the modified Thompson test by using whole-body bioluminescence imaging to replace traditional efficacy testing in experimental models of murine malaria von Caridha, Diana, Hickman, Mark, Xie, Lisa, Ngundam, Franklyn, Milner, Erin, Schenk, Amanda, Butler, Kirk, Nugent, Dylan, Lee, Patricia, Roncal, Norma, Leed, Susan, Hosford, Eve, Lee, Jangwoo, Sciotti, Richard J, Reichard, Gregory, Black, Chad, Kreishman-Deitrick, Mara, Li, Qigui, Vesely, Brian

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SARVision Plus von Reichard, Gregory A

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SARVision Plus by ChemApps von Reichard, Gregory A

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Asymmetric Synthesis of 4,4-Disubstituted-2-Imidazoli-dinones:  Potent NK1 Antagonists von Reichard, Gregory A, Stengone, Carmine, Paliwal, Sunil, Mergelsberg, Ingrid, Majmundar, Sapna, Wang, Cheng, Tiberi, Robert, McPhail, Andrew T, Piwinski, John J, Shih, Neng-Yang

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A New Magnesium-Catalyzed Doubly Diastereoselective anti-Aldol Reaction Leads to a Highly Efficient Process for the Total Synthesis of Lactacystin in Quantity von Corey, E. J, Li, Weidong, Reichard, Gregory A

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Cyclobutane derivatives as potent NK1 selective antagonists von WROBLESKI, Michelle Laci, REICHARD, Gregory A, PALIWAL, Sunil, SHAH, Sapna, TSUI, Hon-Chung, DUFFY, Ruth A, LACHOWICZ, Jean E, MORGAN, Cynthia A, VARTY, Geoffrey B, SHIH, Neng-Yang

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Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions von Shue, Ho-Jane, Chen, Xiao, Schwerdt, John H, Paliwal, Sunil, Blythin, David J, Lin, Ling, Gu, Danlin, Wang, Cheng, Reichard, Gregory A, Wang, Hongwu, Piwinski, John J, Duffy, Ruth A, Lachowicz, Jean E, Coffin, Vicki L, Nomeir, Amin A, Morgan, Cynthia A, Varty, Geoffrey B, Shih, Neng-Yang

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