Optimization of methods for reducing turnaround time and compound consumptionwith echo liquid handling and automation enabling high capacity analysis for ADME screening von Roychowdhury, Shantanu, Martineau, Mitchell, Rehm, Ashley, Patel, Birju

Volltext

National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study von Shield, Kevin, Manthey, Jakob, Rylett, Margaret, Probst, Charlotte, Wettlaufer, Ashley, Parry, Charles D H, Rehm, Jürgen

Volltext

Guidelines for investigating causality of sequence variants in human disease von MacArthur, D. G., Manolio, T. A., Dimmock, D. P., Rehm, H. L., Shendure, J., Abecasis, G. R., Adams, D. R., Altman, R. B., Antonarakis, S. E., Ashley, E. A., Barrett, J. C., Biesecker, L. G., Conrad, D. F., Cooper, G. M., Cox, N. J., Daly, M. J., Gerstein, M. B., Goldstein, D. B., Hirschhorn, J. N., Leal, S. M., Pennacchio, L. A., Stamatoyannopoulos, J. A., Sunyaev, S. R., Valle, D., Voight, B. F., Winckler, W., Gunter, C.

Volltext

A systematic comparison of the global comparative risk assessments for alcohol von Chrystoja, Bethany R., Rehm, Jürgen, Manthey, Jakob, Probst, Charlotte, Wettlaufer, Ashley, Shield, Kevin D.

Volltext

Surveillance of alcohol use through population surveys in the Americas from 2010 to 2019 von Jaswal, Harpreet, Sohi, Ivneet, Chrystoja, Bethany, Imtiaz, Sameer, Franklin, Ari, Wettlaufer, Ashley, Rehm, Jürgen, Monteiro, Maristela, Shield, Kevin

Volltext

Using the ACMG/AMP framework to capture evidence related to predicted and observed impact on splicing: Recommendations from the ClinGen SVI Splicing Subgroup von Walker, Logan C., Hoya, Miguel de la, Wiggins, George A.R., Lindy, Amanda, Vincent, Lisa M., Parsons, Michael T., Canson, Daffodil M., Bis-Brewer, Dana, Cass, Ashley, Tchourbanov, Alexander, Zimmermann, Heather, Byrne, Alicia B., Pesaran, Tina, Karam, Rachid, Harrison, Steven M., Spurdle, Amanda B., Biesecker, Leslie G., Harrison, Steven M., Tayoun, Ahmad A., Berg, Jonathan S., Brenner, Steven E., Cutting, Garry R., Ellard, Sian, Greenblatt, Marc S., Kang, Peter, Karbassi, Izabela, Karchin, Rachel, Mester, Jessica, O’Donnell-Luria, Anne, Pesaran, Tina, Plon, Sharon E., Rehm, Heidi L., Strande, Natasha T., Tavtigian, Sean V., Topper, Scott

Volltext

What is the best indicator of the harmful use of alcohol? A narrative review von Rehm, Jürgen, Crépault, Jean‐François, Wettlaufer, Ashley, Manthey, Jakob, Shield, Kevin

Volltext

The Global Impact of Alcohol Consumption on Premature Mortality and Health in 2016 von Sohi, Ivneet, Franklin, Ari, Chrystoja, Bethany, Wettlaufer, Ashley, Rehm, Jürgen, Shield, Kevin

Volltext

The landscape of reported VUS in multi-gene panel and genomic testing: Time for a change von Rehm, Heidi L., Alaimo, Joseph T., Aradhya, Swaroop, Bayrak-Toydemir, Pinar, Best, Hunter, Brandon, Rhonda, Buchan, Jillian G., Chao, Elizabeth C., Chen, Elaine, Clifford, Jacob, Cohen, Ana S.A., Conlin, Laura K., Das, Soma, Davis, Kyle W., del Gaudio, Daniela, Del Viso, Florencia, DiVincenzo, Christina, Eisenberg, Marcia, Guidugli, Lucia, Hammer, Monia B., Harrison, Steven M., Hatchell, Kathryn E., Dyer, Lindsay Havens, Hoang, Lily U., Holt, James M., Jobanputra, Vaidehi, Karbassi, Izabela D., Kearney, Hutton M., Kelly, Melissa A., Kelly, Jacob M., Kluge, Michelle L., Komala, Timothy, Kruszka, Paul, Lau, Lynette, Lebo, Matthew S., Marshall, Christian R., McKnight, Dianalee, McWalter, Kirsty, Meng, Yan, Nagan, Narasimhan, Neckelmann, Christian S., Neerman, Nir, Niu, Zhiyv, Paolillo, Vitoria K., Paolucci, Sarah A., Perry, Denise, Pesaran, Tina, Radtke, Kelly, Rasmussen, Kristen J., Retterer, Kyle, Saunders, Carol J., Spiteri, Elizabeth, Stanley, Christine, Szuto, Anna, Taft, Ryan J., Thiffault, Isabelle, Thomas, Brittany C., Thomas-Wilson, Amanda, Thorpe, Erin, Tidwell, Timothy J., Towne, Meghan C., Zouk, Hana, Marshall, Christian, Meng, Linyan, Jobanputra, Vaidehi, Taft, Ryan, Ashley, Euan, Nakouzi, Ghunwa, Shen, Wei, Kingsmore, Stephen, Rehm, Heidi

Volltext

Genomic data in the All of Us Research Program von Bick, Alexander G., Metcalf, Ginger A., Mayo, Kelsey R., Lichtenstein, Lee, Rura, Shimon, Carroll, Robert J., Musick, Anjene, Linder, Jodell E., Jordan, I. King, Nagar, Shashwat Deepali, Sharma, Shivam, Meller, Robert, Basford, Melissa, Boerwinkle, Eric, Cicek, Mine S., Doheny, Kimberly F., Eichler, Evan E., Gabriel, Stacey, Gibbs, Richard A., Glazer, David, Harris, Paul A., Jarvik, Gail P., Philippakis, Anthony, Rehm, Heidi L., Roden, Dan M., Thibodeau, Stephen N., Topper, Scott, Blegen, Ashley L., Wirkus, Samantha J., Wagner, Victoria A., Meyer, Jeffrey G., Muzny, Donna M., Venner, Eric, Mawhinney, Michelle Z., Griffith, Sean M. L., Hsu, Elvin, Ling, Hua, Adams, Marcia K., Walker, Kimberly, Hu, Jianhong, Doddapaneni, Harsha, Kovar, Christie L., Murugan, Mullai, Dugan, Shannon, Khan, Ziad, Lennon, Niall J., Austin-Tse, Christina, Banks, Eric, Gatzen, Michael, Gupta, Namrata, Henricks, Emma, Larsson, Katie, McDonough, Sheli, Harrison, Steven M., Kachulis, Christopher, Lebo, Matthew S., Neben, Cynthia L., Steeves, Marcie, Zhou, Alicia Y., Smith, Joshua D., Frazar, Christian D., Davis, Colleen P., Patterson, Karynne E., Wheeler, Marsha M., McGee, Sean, Lockwood, Christina M., Shirts, Brian H., Pritchard, Colin C., Murray, Mitzi L., Vasta, Valeria, Leistritz, Dru, Richardson, Matthew A., Buchan, Jillian G., Radhakrishnan, Aparna, Krumm, Niklas, Ehmen, Brenna W., Schwartz, Sophie, Aster, M. Morgan T., Cibulskis, Kristian, Haessly, Andrea, Asch, Rebecca, Cremer, Aurora, Degatano, Kylee, Shergill, Akum, Gauthier, Laura D., Lee, Samuel K., Hatcher, Aaron, Grant, George B., Brandt, Genevieve R., Covarrubias, Miguel, Able, Ashley, Green, Ashley E., Zhang, Jennifer, Condon, Henry R., Wang, Yuanyuan, Dillon, Moira K., Albach, C. H., Baalawi, Wail, Choi, Seung Hoan, Wang, Xin

Volltext

The Medical Genome Initiative: moving whole-genome sequencing for rare disease diagnosis to the clinic von Marshall, Christian R, Bick, David, Belmont, John W, Taylor, Stacie L, Ashley, Euan, Dimmock, David, Jobanputra, Vaidehi, Kearney, Hutton M, Kulkarni, Shashikant, Rehm, Heidi

Volltext

Estimating the harms and costs of cannabis-attributable collisions in the Canadian provinces von Wettlaufer, Ashley, Florica, Roxana O, Asbridge, Mark, Beirness, Douglas, Brubacher, Jeffrey, Callaghan, Russell, Fischer, Benedikt, Gmel, Gerrit, Imtiaz, Sameer, Mann, Robert E, McKiernan, Anna, Rehm, Jürgen

Volltext

REViewer: haplotype-resolved visualization of read alignments in and around tandem repeats von Dolzhenko, Egor, Weisburd, Ben, Ibañez, Kristina, Rajan-Babu, Indhu-Shree, Anyansi, Christine, Bennett, Mark F, Billingsley, Kimberley, Carroll, Ashley, Clamons, Samuel, Danzi, Matt C, Deshpande, Viraj, Ding, Jinhui, Fazal, Sarah, Halman, Andreas, Jadhav, Bharati, Qiu, Yunjiang, Richmond, Phillip A, Saunders, Christopher T, Scheffler, Konrad, van Vugt, Joke J F A, Zwamborn, Ramona R A J, Chong, Samuel S, Friedman, Jan M, Tucci, Arianna, Rehm, Heidi L, Eberle, Michael A

Volltext

Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells von Kath, Jonas, Du, Weijie, Pruene, Alina, Braun, Tobias, Thommandru, Bernice, Turk, Rolf, Sturgeon, Morgan L., Kurgan, Gavin L., Amini, Leila, Stein, Maik, Zittel, Tatiana, Martini, Stefania, Ostendorf, Lennard, Wilhelm, Andreas, Akyüz, Levent, Rehm, Armin, Höpken, Uta E., Pruß, Axel, Künkele, Annette, Jacobi, Ashley M., Volk, Hans-Dieter, Schmueck-Henneresse, Michael, Stripecke, Renata, Reinke, Petra, Wagner, Dimitrios L.

Volltext

Alcohol, No Ordinary Commodity: policy implications for Canada von Crépault, Jean-François, Naimi, Timothy S, Rehm, Jürgen, Shield, Kevin D, Wells, Samantha, Wettlaufer, Ashley, Babor, Thomas F

Volltext

Targeted Droplet-Digital PCR as a Tool for Novel Deletion Discovery at the DFNB1 Locus von Tayoun, Ahmad N. Abou, Mason-Suares, Heather, Frisella, Ashley L., Bowser, Mark, Duffy, Elizabeth, Mahanta, Lisa, Funke, Birgit, Rehm, Heidi L., Amr, Sami S.

Volltext

Advancing access to genome sequencing for rare genetic disorders: recent progress and call to action von Jobanputra, Vaidehi, Schroeder, Brock, Rehm, Heidi L., Shen, Wei, Spiteri, Elizabeth, Nakouzi, Ghunwa, Taylor, Stacie, Marshall, Christian R., Meng, Linyan, Kingsmore, Stephen F., Ellsworth, Katarzyna, Ashley, Euan, Taft, Ryan J.

Volltext

The effects of alcohol-related harms to others on self-perceived mental well-being in a Canadian sample von Lewis-Laietmark, Candace, Wettlaufer, Ashley, Shield, Kevin D., Giesbrecht, Norman, April, Nicole, Asbridge, Mark, Dell, Colleen, Rehm, Jürgen, Stockwell, Tim

Volltext

public resource facilitating clinical use of genomes von Ball, Madeleine P, Thakuria, Joseph V, Zaranek, Alexander Wait, Clegg, Tom, Rosenbaum, Abraham M, Wu, Xiaodi, Angrist, Misha, Bhak, Jong, Bobe, Jason, Callow, Matthew J, Cano, Carlos, Chou, Michael F, Chung, Wendy K, Douglas, Shawn M, Estep, Preston W, Gore, Athurva, Hulick, Peter, Labarga, Alberto, Lee, Je-Hyuk, Lunshof, Jeantine E, Kim, Byung Chul, Kim, Jong-Il, Li, Zhe, Murray, Michael F, Nilsen, Geoffrey B, Peters, Brock A, Raman, Anugraha M, Rienhoff, Hugh Y, Robasky, Kimberly, Wheeler, Matthew T, Vandewege, Ward, Vorhaus, Daniel B, Yang, Joyce L, Yang, Luhan, Aach, John, Ashley, Euan A, Drmanac, Radoje, Kim, Seong-Jin, Li, Jin Billy, Peshkin, Leonid, Seidman, Christine E, Seo, Jeong-Sun, Zhang, Kun, Rehm, Heidi L, Church, George M

Volltext

Phased whole-genome genetic risk in a family quartet using a major allele reference sequence von Dewey, Frederick E, Chen, Rong, Cordero, Sergio P, Ormond, Kelly E, Caleshu, Colleen, Karczewski, Konrad J, Whirl-Carrillo, Michelle, Wheeler, Matthew T, Dudley, Joel T, Byrnes, Jake K, Cornejo, Omar E, Knowles, Joshua W, Woon, Mark, Sangkuhl, Katrin, Gong, Li, Thorn, Caroline F, Hebert, Joan M, Capriotti, Emidio, David, Sean P, Pavlovic, Aleksandra, West, Anne, Thakuria, Joseph V, Ball, Madeleine P, Zaranek, Alexander W, Rehm, Heidi L, Church, George M, West, John S, Bustamante, Carlos D, Snyder, Michael, Altman, Russ B, Klein, Teri E, Butte, Atul J, Ashley, Euan A

Volltext