Determining the impact of uncharacterized inversions in the human genome by droplet digital PCR von Puig, Marta, Lerga-Jaso, Jon, Giner-Delgado, Carla, Pacheco, Sarai, Izquierdo, David, Delprat, Alejandra, Gayà-Vidal, Magdalena, Regan, Jack F, Karlin-Neumann, George, Cáceres, Mario

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Determining the impact of uncharacterized inversions in the human genome by droplet digital PCR von Puig Font, Marta, Lerga Jaso, Jon, Giner-Delgado, Carla, Pacheco, Sarai, Izquierdo, David, Delprat Obeaga, Alejandra, Gayà Vidal, Magdalena, Regan, Jack F, Karlin Neumann, George, Cáceres Aguilar, Mario

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Determining the impact of uncharacterized inversions in the human genome by droplet digital PCR von Puig Font, Marta, Lerga Jaso, Jon, Giner-Delgado, Carla, Pacheco, Sarai, Izquierdo Fontanills, David, Delprat Obeaga, Alejandra, Gayà Vidal, Magdalena, Regan, Jack F, Karlin Neumann, George, Cáceres Aguilar, Mario

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Assessment of Ki67 in Breast Cancer: Recommendations from the International Ki67 in Breast Cancer Working Group von Dowsett, Mitch, Nielsen, Torsten O., A'Hern, Roger, Bartlett, John, Coombes, R. Charles, Cuzick, Jack, Ellis, Matthew, Henry, N. Lynn, Hugh, Judith C., Lively, Tracy, McShane, Lisa, Paik, Soon, Penault-Llorca, Frederique, Prudkin, Ljudmila, Regan, Meredith, Salter, Janine, Sotiriou, Christos, Smith, Ian E., Viale, Giuseppe, Zujewski, Jo Anne, Hayes, Daniel F.

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Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial von Spinazzi, Eleonora F, Argenziano, Michael G, Upadhyayula, Pavan S, Banu, Matei A, Neira, Justin A, Higgins, Dominique M O, Wu, Peter B, Pereira, Brianna, Mahajan, Aayushi, Humala, Nelson, Al-Dalahmah, Osama, Zhao, Wenting, Save, Akshay V, Gill, Brian J A, Boyett, Deborah M, Marie, Tamara, Furnari, Julia L, Sudhakar, Tejaswi D, Stopka, Sylwia A, Regan, Michael S, Catania, Vanessa, Good, Laura, Zacharoulis, Stergios, Behl, Meenu, Petridis, Petros, Jambawalikar, Sachin, Mintz, Akiva, Lignelli, Angela, Agar, Nathalie Y R, Sims, Peter A, Welch, Mary R, Lassman, Andrew B, Iwamoto, Fabio M, D’Amico, Randy S, Grinband, Jack, Canoll, Peter, Bruce, Jeffrey N

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Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials von Bradley, Rosie, Braybrooke, Jeremy, Gray, Richard, Hills, Robert, Liu, Zulian, Peto, Richard, Davies, Lucy, Dodwell, David, McGale, Paul, Pan, Hongchao, Taylor, Carolyn, Anderson, Stewart, Gelber, Richard, Gianni, Luca, Jacot, William, Joensuu, Heikki, Moreno-Aspitia, Alvaro, Piccart, Martine, Press, Michael, Romond, Edward, Slamon, Dennis, Suman, Vera, Berry, Richard, Boddington, Clare, Clarke, Mike, Davies, Christina, Duane, Fran, Evans, Vaughan, Gay, Jo, Gettins, Lucy, Godwin, Jon, James, Sam, Liu, Hui, MacKinnon, Elizabeth, Mannu, Gurdeep, McHugh, Theresa, Morris, Philip, Read, Simon, Straiton, Ewan, Wang, Yaochen, Crown, John, de Azambuja, Evandro, Delaloge, Suzette, Fung, Helena, Geyer, Charles, Spielmann, Marc, Valagussa, Pinuccia, Albain, Kathy, Arriagada, Rodrigo, Bartlett, John, Bergsten-Nordström, Elizabeth, Bliss, Judith, Brain, Etienne, Carey, Lisa, Coleman, Robert, Cuzick, Jack, Davidson, Nancy, Del Mastro, Lucia, Di Leo, Angelo, Dignam, James, Dowsett, Mitch, Ejlertsen, Bent, Francis, Prue, Gnant, Michael, Goetz, Matthew, Goodwin, Pam, Halpin-Murphy, Pat, Hayes, Dan, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Loibl, Sibylle, Mamounas, Eleftherios P, Martín, Miguel, Mukai, Hirofumi, Nekljudova, Valentina, Norton, Larry, Ohashi, Yasuo, Pierce, Lori, Poortmans, Philip, Raina, Vinod, Rea, Daniel, Regan, Meredith, Robertson, John, Rutgers, Emiel, Spanic, Tanja, Sparano, Joseph, Steger, Guenther, Tang, Gong, Toi, Masakazu, Tutt, Andrew, Viale, Giuseppe, Wang, Xiang, Whelan, Tim, Wilcken, Nicholas, Wolmark, Norman, Cameron, David, Bergh, Jonas, Pritchard, Kathleen I, Swain, Sandra M

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Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26... von Gray, Richard, Liu, Zulian, Peto, Richard, Davies, Lucy, McGale, Paul, Pan, Hongchao, Taylor, Carolyn, Barlow, William, Bliss, Judith, Bruzzi, Paolo, Cameron, David, Fountzilas, George, Loibl, Sibylle, Martin, Miguel, Möbus, Volker, Nekljudova, Valentina, De Placido, Sabino, Untch, Michael, Norton, Larry, Burrett, Julie, Evans, Vaughan, Hills, Robert, James, Sam, Mannu, Gurdeep, Morris, Philip, Wang, Yaochen, Wang, Zhe, Gnant, Michael, Di Leo, Angelo, Dolci, Stella, Larsimont, Denis, Nogaret, Jean Marie, Piccart, Martine, Linn, Sabine, Peer, Petronella, Tjan-Heijnen, Vivianne, Vliek, Sonja, Slamon, Dennis, Bramwell, Vivien H, Chen, Bingshu, Chia, Stephen, Gelmon, Karen, Goss, Paul, Parulekar, Wendy, Pater, Joseph, Rakovitch, Eileen, Shepherd, Lois, Berry, Don, Broadwater, Gloria, Shan, Yi, Xu, Binghe, Zhao, Dong-Bing, Bartelink, Harry, Cufer, Tanja, Poortmans, Philip, Rutgers, Emiel, van de Velde, Cornelis, Carrasco, Eva, Costa, Serban, Gerber, Bernd, Jackisch, Christian, von Minckwitz, Gunter, Giuliano, Mario, De Laurentiis, Michele, Bamia, Christina, Mavroudis, Dimitris, A'Hern, Roger, Sadoon, Mohammad, Costantino, Joe, Dignam, James, Fisher, Bernard, Mamounas, Eleftherios P, Paik, Soon, Redmond, Carol, Wickerham, D Lawrence, Venturini, Marco, Pastorino, Simona, Sertoli, Mario Roberto, Albain, Kathy, Arriagada, Rodrigo, Bergsten Nordström, Elizabeth, Boccardo, Francesco, Coleman, Robert, Correa, Candace, Dowsett, Mitch, Ewertz, Marianne, Goldhirsch, Aron, Hill, Catherine, Jagsi, Reshma, Janni, Wolfgang, Mukai, Hirofumi, Ohashi, Yasuo, Pierce, Lori, Raina, Vinod, Ravdin, Peter, Rea, Daniel, Sparano, Joseph, Tutt, Andrew, Viale, Giuseppe, Zambetti, Milvia

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Plastic surgery procedure unit: A streamlined care model for minor and intermediate procedures: A cost-benefit analysis von Cullen, Shane, Wrafter, Paula F., Jones, Deirdre, Regan, Padraic J., Kelly, Jack L., Hussey, Alan J., McInerney, Niall M.

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Ultra-rare genetic variation in common epilepsies: a case-control sequencing study von Allen, Andrew S, Bellows, Susannah T, Berkovic, Samuel F, Bridgers, Joshua, Burgess, Rosemary, Cavalleri, Gianpiero, Chung, Seo-Kyung, Cossette, Patrick, Delanty, Norman, Dlugos, Dennis, Epstein, Michael P, Freyer, Catharine, Goldstein, David B, Heinzen, Erin L, Hildebrand, Michael S, Johnson, Michael R, Kuzniecky, Ruben, Lowenstein, Daniel H, Marson, Anthony G, Mayeux, Richard, Mebane, Caroline, Mefford, Heather C, O'Brien, Terence J, Ottman, Ruth, Petrou, Steven, Petrovski, Slavgé, Pickrell, William O, Poduri, Annapurna, Radtke, Rodney A, Rees, Mark I, Regan, Brigid M, Ren, Zhong, Scheffer, Ingrid E, Sills, Graeme J, Thomas, Rhys H, Wang, Quanli, Abou-Khalil, Bassel, Alldredge, Brian K, Amrom, Dina, Andermann, Eva, Andermann, Frederick, Bautista, Jocelyn F., Bluvstein, Judith, Boro, Alex, Cascino, Gregory D, Consalvo, Damian, Crumrine, Patricia, Devinsky, Orrin, Fiol, Miguel, Fountain, Nathan B, French, Jacqueline, Friedman, Daniel, Geller, Eric B, Glauser, Tracy, Glynn, Simon, Haas, Kevin, Haut, Sheryl R, Hayward, Jean, Helmers, Sandra L, Joshi, Sucheta, Kanner, Andres, Kirsch, Heidi E, Knowlton, Robert C, Kossoff, Eric H, Kuperman, Rachel, Motika, Paul V, Novotny, Edward J, Paolicchi, Juliann M, Parent, Jack M, Park, Kristen, Sadleir, Lynette G, Shellhaas, Renée A., Sherr, Elliott H, Shih, Jerry J., Shinnar, Shlomo, Singh, Rani K, Sirven, Joseph, Smith, Michael C, Sullivan, Joseph, Thio, Liu Lin, Venkat, Anu, Vining, Eileen P.G, Von Allmen, Gretchen K, Weisenberg, Judith L, Widdess-Walsh, Peter, Winawer, Melodie R

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High‐risk squamous cell carcinoma of the ear — A potential role for sentinel node biopsy von Beecher, Suzanne, Wrafter, Paula F., Joyce, Cormac W., Regan, Padraic J., Kelly, Jack L.

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Antibody Removal Before ABO-Incompatible Renal Transplantation: How Much Plasma Exchange Is Therapeutic? von LAWRENCE, Christopher, GALLIFORD, Jaek W, WILLIEOMBE, Michelle K, MELEAN, Adam G, LESABE, Mary, ROWAN, Fiona, PAPALOIS, Vassilios, REGAN, Fiona, TAUBE, David

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HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2 von Bartlett, John M.S, Ahmed, Ikhlaaq, Regan, Meredith M, Sestak, Ivana, Mallon, Elizabeth A, Dell'Orto, Patrizia, Thürlimann, Beat, Seynaeve, Caroline, Putter, Hein, Van de Velde, Cornelis J.H, Brookes, Cassandra L, Forbes, John F, Viale, Giuseppe, Cuzick, Jack, Dowsett, Mitchell, Rea, Daniel W

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Long-term effects of vitamins C and E, β-carotene, and zinc on age-related macular degeneration: AREDS report no. 35 von Chew, Emily Y, Clemons, Traci E, Agrón, Elvira, Sperduto, Robert D, Sangiovanni, John Paul, Kurinij, Natalie, Davis, Matthew D

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Current State of and Future Opportunities for Prediction in Microbiome Research: Report from the Mid-Atlantic Microbiome Meet-up in Baltimore on 9 January 2019 von Sakowski, Eric, Uritskiy, Gherman, Cooper, Rachel, Gomes, Maya, McLaren, Michael R., Meisel, Jacquelyn S., Mickol, Rebecca L., Mintz, C. David, Mongodin, Emmanuel F., Pop, Mihai, Rahman, Mohammad Arifur, Sanchez, Alvaro, Timp, Winston, Vela, Jeseth Delgado, Wolz, Carly Muletz, Zackular, Joseph P., Chopyk, Jessica, Commichaux, Seth, Davis, Meghan, Dluzen, Douglas, Ganesan, Sukirth M., Haruna, Muyideen, Nasko, Dan, Regan, Mary J., Sarria, Saul, Shah, Nidhi, Stacy, Brook, Taylor, Dylan, DiRuggiero, Jocelyne, Preheim, Sarah P.

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International Interlaboratory Digital PCR Study Demonstrating High Reproducibility for the Measurement of a Rare Sequence Variant von Whale, Alexandra S, Devonshire, Alison S, Karlin-Neumann, George, Regan, Jack, Javier, Leanne, Cowen, Simon, Fernandez-Gonzalez, Ana, Jones, Gerwyn M, Redshaw, Nicholas, Beck, Julia, Berger, Andreas W, Combaret, Valérie, Dahl Kjersgaard, Nina, Davis, Lisa, Fina, Frederic, Forshew, Tim, Fredslund Andersen, Rikke, Galbiati, Silvia, González Hernández, Álvaro, Haynes, Charles A, Janku, Filip, Lacave, Roger, Lee, Justin, Mistry, Vilas, Pender, Alexandra, Pradines, Anne, Proudhon, Charlotte, Saal, Lao H, Stieglitz, Elliot, Ulrich, Bryan, Foy, Carole A, Parkes, Helen, Tzonev, Svilen, Huggett, Jim F

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Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group von Amgad, Mohamed, Stovgaard, Elisabeth Specht, Balslev, Eva, Thagaard, Jeppe, Chen, Weijie, Dudgeon, Sarah, Sharma, Ashish, Kerner, Jennifer K., Denkert, Carsten, Yuan, Yinyin, AbdulJabbar, Khalid, Wienert, Stephan, Savas, Peter, Voorwerk, Leonie, Beck, Andrew H., Madabhushi, Anant, Hartman, Johan, Sebastian, Manu M., Horlings, Hugo M., Hudeček, Jan, Ciompi, Francesco, Moore, David A., Singh, Rajendra, Roblin, Elvire, Balancin, Marcelo Luiz, Mathieu, Marie-Christine, Lennerz, Jochen K., Kirtani, Pawan, Chen, I-Chun, Braybrooke, Jeremy P., Pruneri, Giancarlo, Demaria, Sandra, Adams, Sylvia, Schnitt, Stuart J., Lakhani, Sunil R., Rojo, Federico, Comerma, Laura, Badve, Sunil S., Khojasteh, Mehrnoush, Symmans, W. Fraser, Sotiriou, Christos, Gonzalez-Ericsson, Paula, Pogue-Geile, Katherine L., Kim, Rim S., Rimm, David L., Viale, Giuseppe, Hewitt, Stephen M., Bartlett, John M. S., Penault-Llorca, Frédérique, Goel, Shom, Lien, Huang-Chun, Loibl, Sibylle, Kos, Zuzana, Loi, Sherene, Hanna, Matthew G., Michiels, Stefan, Kok, Marleen, Nielsen, Torsten O., Lazar, Alexander J., Bago-Horvath, Zsuzsanna, Kooreman, Loes F. S., van der Laak, Jeroen A. W. M., Saltz, Joel, Gallas, Brandon D., Kurkure, Uday, Barnes, Michael, Salgado, Roberto, Cooper, Lee A. D.

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High-risk squamous cell carcinoma of the ear - A potential role for sentinel node biopsy: High risk SCCS of the ear and sentinel node biopsy von Beecher, Suzanne, Wrafter, Paula F., Joyce, Cormac W., Regan, Padraic J., Kelly, Jack L.

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Association of ultra‐rare coding variants with genetic generalized epilepsy: A case–control whole exome sequencing study von Stanley, Kate E., Bobbili, Dheeraj R., Dhindsa, Ryan S., May, Patrick, Alldredge, Brian K., Allen, Andrew S., Altmüller, Janine, Amrom, Dina, Andermann, Eva, Auce, Pauls, Avbersek, Andreja, Bautista, Jocelyn F., Becker, Felicitas, Bellows, Susannah T., Berghuis, Bianca, Bluvstein, Judith, Boro, Alex, Burgess, Rosemary, Caglayan, Hande, Cascino, Gregory D., Chung, Seo‐Kyung, Cieuta‐Walti, Cécile, Consalvo, Damian, Cossette, Patrick, Crumrine, Patricia, Delanty, Norman, Depondt, Chantal, Desbiens, Richard, Dlugos, Dennis, Epstein, Michael P., Everett, Kate, Fountain, Nathan B., Francis, Ben, French, Jacqueline, Friedman, Daniel, Geller, Eric B., Girard, Simon, Glauser, Tracy, Glynn, Simon, Gravel, Micheline, Haas, Kevin, Haut, Sheryl R., Heinzen, Erin L., Helbig, Ingo, Hildebrand, Michael S., Jorgensen, Andrea, Joshi, Sucheta, Kirsch, Heidi E., Knowlton, Robert C., Koeleman, Bobby P. C., Kossoff, Eric H., Krause, Roland, Kunz, Wolfram S., Langley, Sarah R., LeGuern, Eric, Lerche, Holger, Leu, Costin, Lortie, Anne, Marson, Anthony G., Mebane, Caroline, Mefford, Heather C., Meloche, Caroline, Motika, Paul V., Muhle, Hiltrud, Nabbout, Rima, Nguyen, Dang K., Nikanorova, Marina, Novotny, Edward J., Ottman, Ruth, O’Brien, Terence J., Paolicchi, Juliann M., Parent, Jack M., Peter, Sarah, Petrou, Steven, Pickrell, William O., Poduri, Annapurna, Radtke, Rodney A., Rees, Mark I., Regan, Brigid M., Sadleir, Lynette G., Sander, Josemir W., Sander, Thomas, Scheffer, Ingrid E., Singh, Rani K., Sirven, Joseph, Sisodiya, Sanjay M., Smith, Michael C., Sonsma, Anja C. M., Sullivan, Joseph, Thio, Liu Lin, Thomas, Rhys H., Venkat, Anu, Von Allmen, Gretchen K., Wang, Quanli, Weber, Yvonne G., Weckhuysen, Sarah, Widdess‐Walsh, Peter, Winawer, Melodie R., Wolking, Stefan, Zimprich, Fritz

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Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-center, phase 1b trial von Spinazzi, Eleonora F., Argenziano, Michael G., Upadhyayula, Pavan S., Banu, Matei A., Neira, Justin A., Higgins, Dominique M.O., Wu, Peter B., Pereira, Brianna, Mahajan, Aayushi, Humala, Nelson, Al-Dalahmah, Osama, Zhao, Wenting, Save, Akshay V., Gill, Brian JA, Boyett, Deborah M., Marie, Tamara, Furnari, Julia L, Sudhakar, Tejaswi D., Stopka, Sylwia A., Regan, Michael S., Catania, Vanessa, Good, Laura, Zacharoulis, Stergios, Behl, Meenu, Petridis, Petros, Jambawalikar, Sachin, Mintz, Akiva, Lignelli, Angela, Agar, Nathalie Y.R., Sims, Peter A., Welch, Mary R., Lassman, Andrew B., Iwamoto, Fabio M., D’Amico, Randy S., Grinband, Jack, Canoll, Peter, Bruce, Jeffrey N.

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Peer recovery coaches in general medical settings: Changes in utilization, treatment engagement, and opioid use von Magidson, Jessica F., Regan, Susan, Powell, Elizabeth, Jack, Helen E., Herman, Grace E., Zaro, Christopher, Kane, Martha T., Wakeman, Sarah E.

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