Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology von PAPPOLLA, M. A, BRYANT-THOMAS, WOLOZIN, B, SANO, M, CRUZ-SANCHEZ, F. F, THAL, L. J, PETANCESKA, S. S, REFOLO, L. M, HERBERT, D, PACHECO, J, GARCIA, M. Fabra, MANJON, M, GIRONES, X, HENRY, T. L, MATSUBARA, E, ZAMBON, D

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A Cholesterol-Lowering Drug Reduces β-Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease von Refolo, L.M., Pappolla, M.A., LaFrancois, J., Malester, B., Schmidt, S.D., Thomas-Bryant, T., Tint, G.S., Wang, R., Mercken, M., Petanceska, S.S., Duff, K.E.

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Modulation of Aβ peptides by estrogen in mouse models von Zheng, H., Xu, H., Uljon, S. N., Gross, R., Hardy, K., Gaynor, J., Lafrancois, J., Simpkins, J., Refolo, L. M., Petanceska, S., Wang, R., Duff, K.

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Characterization of Pathology in Transgenic Mice Over-Expressing Human Genomic and cDNA Tau Transgenes von Duff, K., Knight, H., Refolo, L.M., Sanders, S., Yu, X., Picciano, M., Malester, B., Hutton, M., Adamson, J., Goedert, M., Burki, K., Davies, P.

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Statin therapy for Alzheimer's disease: will it work? von Petanceska, Suzana S, DeRosa, Steven, Olm, Vicki, Diaz, Nichole, Sharma, Ali, Thomas-Bryant, Tara, Duff, Karen, Pappolla, Miguel, Refolo, Lorenzo M

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Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model von Refolo, Lorenzo M., Pappolla, Miguel A., Malester, Brian, LaFrancois, John, Bryant-Thomas, Tara, Wang, Rong, Tint, G.Stephen, Sambamurti, Kumar, Duff, Karen

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Cholesterol, oxidative stress, and Alzheimer’s disease: expanding the horizons of pathogenesis von Pappolla, Miguel A, Smith, Mark A, Bryant-Thomas, Tara, Bazan, Nicolas, Petanceska, Suzana, Perry, George, Thal, Leon J, Sano, Mary, Refolo, Lorenzo M

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The Alzheimer amyloid precursor is associated with the detergent- insoluble cytoskeleton von Refolo, LM, Wittenberg, IS, Friedrich, VL, Jr, Robakis, NK

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Intracellular Cyclic AMP Inhibits Constitutive and Phorbol Ester‐Stimulated Secretory Cleavage of Amyloid Precursor Protein von Efthimiopoulos, Spiros, Punj, Suzy, Manolopoulos, Vangelis, Pangalos, Menelas, Wang, Gian P., Refolo, Lawrence M., Robakis, Nikolaos K.

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Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization von Gandhi, Swetal, Refolo, Lorenzo M, Sambamurti, Kumar

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Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization von Refolo, L. M., Sambamurti, K., Efthimiopoulos, S., Pappolla, M. A., Robakis, N. K.

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Bacterial expression, purification, and functional mapping of the amyloid beta/A4 protein precursor von Roch, J M, Shapiro, I P, Sundsmo, M P, Otero, D A, Refolo, L M, Robakis, N K, Saitoh, T

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A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43) von Eckman, C B, Mehta, N D, Crook, R, Perez-tur, J, Prihar, G, Pfeiffer, E, Graff-Radford, N, Hinder, P, Yager, D, Zenk, B, Refolo, L M, Prada, C M, Younkin, S G, Hutton, M, Hardy, J

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Nerve and epidermal growth factors induce the release of the Alzheimer Amyloid precursor from PC 12 cell cultures von Refolo, Lawrence M., Salton, Steven R.J., Anderson, John P., Mehta, Pankaj, Robakis, Nikolaos K.

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The Alzheimer's amyloid precursor protein is produced by type I astrocytes in primary cultures of rat neuroglia von Berkenbosch, F., Refolo, L. M., Friedrich Jr, V. L., Casper, D., Blum, M., Robakis, Nikolaos K.

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Differential brain expression of the Alzheimer's amyloid precursor protein von Anderson, J.P., Refolo, L.M., Wallace, W., Mehta, P., Krishnamurthi, M., Gotlib, J., Bierer, L., Haroutunian, V., Perl, D., Robakis, N.K.

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Changes in apolipoprotein E expression in response to dietary and pharmacological modulation of cholesterol von Petanceska, Suzana S, DeRosa, Steven, Sharma, Ali, Diaz, Nichole, Duff, Karen, Tint, Steven G, Refolo, Lorenzo M, Pappolla, Miguel

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Study of the phorbol ester effect on Alzheimer amyloid precursor processing: Sequence requirements and involvement of a Cholera toxin sensitive protein von Efthimiopoulos, S., Felsenstein, K. M., Sambamurti, K., Robakis, N. K., Refolo, L. M.

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Apolipoprotein E4 as a target for developing new therapeutics for Alzheimer's disease von Refolo, Lorenzo M, Fillit, Howard M

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Heat-shocked Neuronal PC12 Cells Reveal Alzheimer's Disease-associated Alterations in Amyloid Precursor Protein and Tau von JOHNSON, G., REFOLO, L. M., WALLACE, W.

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