Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia von Chen, Lisa S., Redkar, Sanjeev, Taverna, Pietro, Cortes, Jorge E., Gandhi, Varsha

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Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells von Chen, Lisa S., Redkar, Sanjeev, Bearss, David, Wierda, William G., Gandhi, Varsha

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S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth von Chuang, Jody C, Warner, Steven L, Vollmer, David, Vankayalapati, Hariprasad, Redkar, Sanjeev, Bearss, David J, Qiu, Xiangning, Yoo, Christine B, Jones, Peter A

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Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides von YOO, Christine B, JEONG, Shinwu, EGGER, Gerda, GANGNING LIANG, PHIASIVONGSA, Pasit, CHUNLIN TANG, REDKAR, Sanjeev, JONES, Peter A

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Abstract 2096: Bozitinib, a highly selective inhibitor of cMet, demonstrates robust activity in gastric, lung, hepatic and pancreatic in vivo models von Shih, Joe, Zhong, Boyu, Shi, Hepeng, Xue, David, Choy, Gavin S., Redkar, Sanjeev

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Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes von Mumenthaler, Shannon M, Ng, Patricia Y B, Hodge, Amanda, Bearss, David, Berk, Gregory, Kanekal, Sarath, Redkar, Sanjeev, Taverna, Pietro, Agus, David B, Jain, Anjali

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Erratum to: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines von Phillip, Cornel Joseph, Zaman, Shadia, Shentu, Shujun, Balakrishnan, Kumudha, Zhang, Jiexin, Baladandayuthapani, Veera, Taverna, Pietro, Redkar, Sanjeev, Wang, Michael, Stellrecht, Christine Marie, Gandhi, Varsha

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S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis) von Lavelle, Donald, Saunthararajah, Yogen, Vaitkus, Kestis, Singh, Mahipal, Banzon, Virryan, Phiasivongsva, Pasit, Redkar, Sanjeev, Kanekal, Sarath, Bearss, David, Shi, Chongtie, Inloes, Roger, DeSimone, Joseph

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RETRACTED: A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation von Datta, Jharna, Ghoshal, Kalpana, Denny, William A., Gamage, Swarna A., Brooke, Darby G., Phiasivongsa, Pasit, Redkar, Sanjeev, Jacob, Samson T.

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Abstract 2205: CBT-102, an oral small molecule multi-kinase inhibitor, demonstrates favorable CSF-1R activity, offering means of controlling tumor associated macrophages von Liu, Elaine, Yang, Lan, Choy, Gavin, Zhang, Xiaoling, Pearce, Tillman, Reddy, Mamatha, Redkar, Sanjeev, Shi, Qian

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A New Class of Quinoline-Based DNA Hypomethylating Agents Reactivates Tumor Suppressor Genes by Blocking DNA Methyltransferase 1 Activity and Inducing Its Degradation von DATTA, Jharna, GHOSHAL, Kalpana, DENNY, William A, GAMAGE, Swarna A, BROOKE, Darby G, PHIASIVONGSA, Pasit, REDKAR, Sanjeev, JACOB, Samson T

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Cross-flow microfiltration with high-frequency reverse filtration von Redkar, Sanjeev G., Davis, Robert H.

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Expect the Unexpected–Screen Your Screens von Ravivarapu, Harish, Redkar, Sanjeev

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Abstract 3945: CBT-102, an oral multi-kinase small molecule, demonstrates favorable activity in human hepatocellular carcinoma animal models and cardiac safety in rabbit Purkinje a... von Kanekal, Sarath, Zhang, Xiquan, Song, Yanrui, Wenmiao, Tan, Zhang, Juan, Zhang, Deyi, Li, Henry, Reddy, Mamatha, Choy, Gavin, Redkar, Sanjeev

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Activity of CBT-501, a novel humanized anti-PD-1 antibody, in a humanized genetically engineered mouse model of colon carcinoma von Zhou, Qing, Nian, Weihong, Sun, Ziyong, Qiu, Junzhuan, Wang, Zhun, Choy, Gavin, Redkar, Sanjeev

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CTNI-01. A PHASE 1-2 CLINICAL TRIAL OF EO1001 (APL-122), A NOVEL IRREVERSIBLE PAN-ERBB INHIBITOR WITH PROMISING BRAIN PENETRATION von Frentzas, Sophia, Richardson, Gary, Bacha, Jeffrey, Kanekal, Sarath, Sankar, Neil, Shen, Wang, Redkar, Sanjeev, Lai, Chinglin, Yu, Peony, Nisbet, Ian, Skoff, Kathy, Wheeler, Helen, Pedersen, Harry, Zhong, Wang Zhen, Brown, Dennis

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Design, Synthesis, and Pharmacological Evaluation of Fluorinated Tetrahydrouridine Derivatives as Inhibitors of Cytidine Deaminase von Ferraris, Dana, Duvall, Bridget, Delahanty, Greg, Mistry, Bipin, Alt, Jesse, Rojas, Camilo, Rowbottom, Christopher, Sanders, Kristen, Schuck, Edgar, Huang, Kuan-Chun, Redkar, Sanjeev, Slusher, Barbara B, Tsukamoto, Takashi

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Abstract A200: CBT-502 (TQB2450), a novel anti-PD-L1 antibody, demonstrates favorable activity in MC-38/H-11 murine colon and A375 human melanoma animal models von Wei, Zhao, Yang, Ling, Li, Yingchun, Lu, Jiansheng, Zhang, Xiquan, Tian, Xin, Zha, Jiping, Sun, Ziyong, Qiu, Junzhuan, Wang, Zhun, Reddy, Mamatha, Choy, Gavin S., Redkar, Sanjeev

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Phase 1B study of amuvatinib in combination with five standard cancer therapies in adults with advanced solid tumors von Mita, Monica, Gordon, Michael, Rosen, Lee, Kapoor, Nirmal, Choy, Gavin, Redkar, Sanjeev, Taverna, Pietro, Oganesian, Aram, Sahai, Amarpal, Azab, Mohammad, Bristow, Robert, Tolcher, Anthony W.

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Preclinical Data In Cynomolgus (cyn) Monkeys Of ASTX727, a Novel Oral Hypomethylating Agent (HMA) Composed Of Low-Dose Oral Decitabine Combined With a Novel Cytidine Deaminase Inhi... von Oganesian, Aram, Redkar, Sanjeev, Taverna, Pietro, Joshi-Hangal, Rajashree, Azab, Mohammad

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