Mast Cells: A New Frontier for Cancer Immunotherapy von Lichterman, Jake N., Reddy, Sangeetha M.

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Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells von Gall, Victor A, Philips, Anne V, Qiao, Na, Clise-Dwyer, Karen, Perakis, Alexander A, Zhang, Mao, Clifton, Guy T, Sukhumalchandra, Pariya, Ma, Qing, Reddy, Sangeetha M, Yu, Dihua, Molldrem, Jeffrey J, Peoples, George E, Alatrash, Gheath, Mittendorf, Elizabeth A

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Considerations for treatment duration in responders to immune checkpoint inhibitors von Marron, Thomas U, Ryan, Aideen E, Reddy, Sangeetha M, Kaczanowska, Sabina, Younis, Rania H, Thakkar, Dipti, Zhang, Jiajia, Bartkowiak, Todd, Howard, Rachel, Anderson, Kristin G, Olson, Daniel, Naqash, Abdul Rafeh, Patel, Ravi B, Sachdev, Esha, Rodriguez-Ruiz, Maria E, Sheffer, Michal, Church, Sarah, Fuhrman, Christopher, Overacre-Delgoffe, Abigail, Nguyen, Rosa, Florou, Vaia, Thaxton, Jessica E, Aggen, David H, Guerriero, Jennifer L

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Dendritic cell therapy augments antitumor immunity triggered by CDK4/6 inhibition and immune checkpoint blockade by unleashing systemic CD4 T-cell responses von Kumar, Amrendra, Ramani, Vijay, Bharti, Vijaya, de Lima Bellan, Daniel, Saleh, Nabil, Uzhachenko, Roman, Shen, Chengli, Arteaga, Carlos, Richmond, Ann, Reddy, Sangeetha M, Vilgelm, Anna

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Monitoring immune responses in the tumor microenvironment von Wargo, Jennifer A, Reddy, Sangeetha M, Reuben, Alexandre, Sharma, Padmanee

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Whole-genome sequencing of phenotypically distinct inflammatory breast cancers reveals similar genomic alterations to non-inflammatory breast cancers von Li, Xiaotong, Kumar, Sushant, Harmanci, Arif, Li, Shantao, Kitchen, Robert R., Zhang, Yan, Wali, Vikram B., Reddy, Sangeetha M., Woodward, Wendy A., Reuben, James M., Rozowsky, Joel, Hatzis, Christos, Ueno, Naoto T., Krishnamurthy, Savitri, Pusztai, Lajos, Gerstein, Mark

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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma von Sade-Feldman, Moshe, Yizhak, Keren, Bjorgaard, Stacey L., Ray, John P., de Boer, Carl G., Jenkins, Russell W., Lieb, David J., Chen, Jonathan H., Frederick, Dennie T., Barzily-Rokni, Michal, Freeman, Samuel S., Reuben, Alexandre, Hoover, Paul J., Villani, Alexandra-Chloé, Ivanova, Elena, Portell, Andrew, Lizotte, Patrick H., Aref, Amir R., Eliane, Jean-Pierre, Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Li, Bo, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Cooper, Zachary A., Paweletz, Cloud P., Barbie, David A., Stemmer-Rachamimov, Anat, Flaherty, Keith T., Wargo, Jennifer A., Boland, Genevieve M., Sullivan, Ryan J., Getz, Gad, Hacohen, Nir

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Digital droplet PCR analysis of organoids generated from mouse mammary tumors demonstrates proof-of-concept capture of tumor heterogeneity von Lake, Katherine E, Colonnetta, Megan M, Smith, Clayton A, Saunders, Kaitlyn, Martinez-Algarin, Kenneth, Mohta, Sakshi, Pena, Jacob, McArthur, Heather L, Reddy, Sangeetha M, Roussos Torres, Evanthia T, Chen, Elizabeth H, Chan, Isaac S

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Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma von Amaria, Rodabe N., Reddy, Sangeetha M., Tawbi, Hussein A., Davies, Michael A., Ross, Merrick I., Glitza, Isabella C., Cormier, Janice N., Lewis, Carol, Hwu, Wen-Jen, Hanna, Ehab, Diab, Adi, Wong, Michael K., Royal, Richard, Gross, Neil, Weber, Randal, Lai, Stephen Y., Ehlers, Richard, Blando, Jorge, Milton, Denái R., Woodman, Scott, Kageyama, Robin, Wells, Daniel K., Hwu, Patrick, Patel, Sapna P., Lucci, Anthony, Hessel, Amy, Lee, Jeffrey E., Gershenwald, Jeffrey, Simpson, Lauren, Burton, Elizabeth M., Posada, Liberty, Haydu, Lauren, Wang, Linghua, Zhang, Shaojun, Lazar, Alexander J., Hudgens, Courtney W., Gopalakrishnan, Vancheswaran, Reuben, Alexandre, Andrews, Miles C., Spencer, Christine N., Prieto, Victor, Sharma, Padmanee, Allison, James, Tetzlaff, Michael T., Wargo, Jennifer A.

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Quantitative Sensory Testing at Baseline and During Cycle 1 Oxaliplatin Infusion Detects Subclinical Peripheral Neuropathy and Predicts Clinically Overt Chronic Neuropathy in Gastr... von Reddy, Sangeetha M, Vergo, Maxwell T, Paice, Judith A, Kwon, Nancy, Helenowski, Irene B, Benson, Al B, Mulcahy, Mary F, Nimeiri, Halla S, Harden, Robert N

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Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade von Chen, Pei-Ling, Roh, Whijae, Reuben, Alexandre, Cooper, Zachary A, Spencer, Christine N, Prieto, Peter A, Miller, John P, Bassett, Roland L, Gopalakrishnan, Vancheswaran, Wani, Khalida, De Macedo, Mariana Petaccia, Austin-Breneman, Jacob L, Jiang, Hong, Chang, Qing, Reddy, Sangeetha M, Chen, Wei-Shen, Tetzlaff, Michael T, Broaddus, Russell J, Davies, Michael A, Gershenwald, Jeffrey E, Haydu, Lauren, Lazar, Alexander J, Patel, Sapna P, Hwu, Patrick, Hwu, Wen-Jen, Diab, Adi, Glitza, Isabella C, Woodman, Scott E, Vence, Luis M, Wistuba, Ignacio I, Amaria, Rodabe N, Kwong, Lawrence N, Prieto, Victor, Davis, R Eric, Ma, Wencai, Overwijk, Willem W, Sharpe, Arlene H, Hu, Jianhua, Futreal, P Andrew, Blando, Jorge, Sharma, Padmanee, Allison, James P, Chin, Lynda, Wargo, Jennifer A

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Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy von Reddy, Sangeetha M., Reuben, Alexandre, Wargo, Jennifer A.

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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma von Sade-Feldman, Moshe, Yizhak, Keren, Bjorgaard, Stacey L., Ray, John P., de Boer, Carl G., Jenkins, Russell W., Lieb, David J., Chen, Jonathan H., Frederick, Dennie T., Barzily-Rokni, Michal, Freeman, Samuel S., Reuben, Alexandre, Hoover, Paul J., Villani, Alexandra-Chloé, Ivanova, Elena, Portell, Andrew, Lizotte, Patrick H., Aref, Amir R., Eliane, Jean-Pierre, Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Li, Bo, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Cooper, Zachary A., Paweletz, Cloud P., Barbie, David A., Stemmer-Rachamimov, Anat, Flaherty, Keith T., Wargo, Jennifer A., Boland, Genevieve M., Sullivan, Ryan J., Getz, Gad, Hacohen, Nir

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Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer von Reddy, Sangeetha M, Reuben, Alexandre, Barua, Souptik, Jiang, Hong, Zhang, Shaojun, Wang, Linghua, Gopalakrishnan, Vancheswaran, Hudgens, Courtney W, Tetzlaff, Michael T, Reuben, James M, Tsujikawa, Takahiro, Coussens, Lisa M, Wani, Khalida, He, Yan, Villareal, Lily, Wood, Anita, Rao, Arvind, Woodward, Wendy A, Ueno, Naoto T, Krishnamurthy, Savitri, Wargo, Jennifer A, Mittendorf, Elizabeth A

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Interaction of molecular alterations with immune response in melanoma von Szczepaniak Sloane, Robert A., Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Zhang, Xue, Reuben, Alexandre, Wargo, Jennifer A.

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Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma von Mitra, Akash, Andrews, Miles C., Roh, Whijae, De Macedo, Marianna Petaccia, Hudgens, Courtney W., Carapeto, Fernando, Singh, Shailbala, Reuben, Alexandre, Wang, Feng, Mao, Xizeng, Song, Xingzhi, Wani, Khalida, Tippen, Samantha, Ng, Kwok-Shing, Schalck, Aislyn, Sakellariou-Thompson, Donald A., Chen, Eveline, Reddy, Sangeetha M., Spencer, Christine N., Wiesnoski, Diana, Little, Latasha D., Gumbs, Curtis, Cooper, Zachary A., Burton, Elizabeth M., Hwu, Patrick, Davies, Michael A., Zhang, Jianhua, Bernatchez, Chantale, Navin, Nicholas, Sharma, Padmanee, Allison, James P., Wargo, Jennifer A., Yee, Cassian, Tetzlaff, Michael T., Hwu, Wen-Jen, Lazar, Alexander J., Futreal, P. Andrew

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Epigenetic Repression of STING by MYC Promotes Immune Evasion and Resistance to Immune Checkpoint Inhibitors in Triple-Negative Breast Cancer von Lee, Kyung-Min, Lin, Chang-Ching, Servetto, Alberto, Bae, Joonbeom, Kandagatla, Vishal, Ye, Dan, Kim, GunMin, Sudhan, Dhivya R, Mendiratta, Saurabh, González Ericsson, Paula I, Balko, Justin M, Lee, Jeon, Barnes, Spencer, Malladi, Venkat S, Tabrizi, Siamak, Reddy, Sangeetha M, Yum, Seoyun, Chang, Ching-Wei, Hutchinson, Katherine E, Yost, Susan E, Yuan, Yuan, Chen, Zhijian J, Fu, Yang-Xin, Hanker, Ariella B, Arteaga, Carlos L

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Generating and Imaging Mouse and Human Epithelial Organoids from Normal and Tumor Mammary Tissue Without Passaging von Cornelius, Serena L, Colonnetta, Megan M, Lake, Katherine E, Smith, Clayton A, Zhang, Yu-An, Roussos-Torres, Evanthia T, Reddy, Sangeetha M, Chen, Elizabeth H, Chan, Isaac S

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A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response von Xu, Lily, Saunders, Kaitlyn, Huang, Shao-Po, Knutsdottir, Hildur, Martinez-Algarin, Kenneth, Terrazas, Isabella, Chen, Kenian, McArthur, Heather M., Maués, Julia, Hodgdon, Christine, Reddy, Sangeetha M., Roussos Torres, Evanthia T., Xu, Lin, Chan, Isaac S.

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796 Pegylated liposomal doxorubicin chemotherapy, Flt3 ligand, and CD40 agonist triplet combination improves tumor control in breast cancers von Nooka, Shruthi, Mylabathula, Preteesh Leo, Zhu, James, Vu, Ashley, Kumari, Sharda, Chan, Isaac, Reddy, Sangeetha M

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