A phase 2 and biomarker study of cabozantinib in patients with advanced cholangiocarcinoma von Goyal, Lipika, Zheng, Hui, Yurgelun, Matthew B., Abrams, Thomas A., Allen, Jill N., Cleary, James M., Knowles, Michelle, Regan, Eileen, Reardon, Amanda, Khachatryan, Anna, Jain, Rakesh K., Nardi, Valentina, Borger, Darrell R., Duda, Dan G., Zhu, Andrew X.

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A Phase II and Biomarker Study of Cabozantinib in Patients with Advanced Cholangiocarcinoma von Goyal, Lipika, Zheng, Hui, Yurgelun, Matthew B., Abrams, Thomas A., Allen, Jill N., Cleary, James M., Knowles, Michelle, Regan, Eileen, Reardon, Amanda, Khachatryan, Anna, Jain, Rakesh K., Nardi, Valentina, Borger, Darrell R., Duda, Dan G., Zhu, Andrew X.

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Phase II trial of cabozantinib in patients with carcinoid and pancreatic neuroendocrine tumors (pNET) von Chan, Jennifer A., Faris, Jason Edward, Murphy, Janet E., Blaszkowsky, Lawrence Scott, Kwak, Eunice Lee, McCleary, Nadine Jackson, Fuchs, Charles S., Meyerhardt, Jeffrey A., Ng, Kimmie, Zhu, Andrew X., Abrams, Thomas Adam, Wolpin, Brian M., Zhang, Sui, Reardon, Amanda, Fitzpatrick, Bridget, Kulke, Matthew H., Ryan, David P.

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Comparison of rapid vs in-depth qualitative analytic methods from a process evaluation of academic detailing in the Veterans Health Administration von Gale, Randall C, Wu, Justina, Erhardt, Taryn, Bounthavong, Mark, Reardon, Caitlin M, Damschroder, Laura J, Midboe, Amanda M

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Advanced MRI assessment to predict benefit of anti-programmed cell death 1 protein immunotherapy response in patients with recurrent glioblastoma von Qin, Lei, Li, Xiang, Stroiney, Amanda, Qu, Jinrong, Helgager, Jeffrey, Reardon, David A., Young, Geoffrey S.

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Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors von Guidon, Amanda C, Burton, Leeann B, Chwalisz, Bart K, Hillis, James, Schaller, Teilo H, Amato, Anthony A, Betof Warner, Allison, Brastianos, Priscilla K, Cho, Tracey A, Clardy, Stacey L, Cohen, Justine V, Dietrich, Jorg, Dougan, Michael, Doughty, Christopher T, Dubey, Divyanshu, Gelfand, Jeffrey M, Guptill, Jeffrey T, Johnson, Douglas B, Juel, Vern C, Kadish, Robert, Kolb, Noah, LeBoeuf, Nicole R, Linnoila, Jenny, Mammen, Andrew L, Martinez-Lage, Maria, Mooradian, Meghan J, Naidoo, Jarushka, Neilan, Tomas G, Reardon, David A, Rubin, Krista M, Santomasso, Bianca D, Sullivan, Ryan J, Wang, Nancy, Woodman, Karin, Zubiri, Leyre, Louv, William C, Reynolds, Kerry L

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An epigenetically inherited UV hyper-resistance phenotype in Saccharomyces cerevisiae von Reardon, Rachel M, Walsh, Amanda K, Larsen, Clairine I, Schmidberger, LauraAnn H, Morrow, Lillian A, Thompson, Adriane E, Wellik, Isabel M, Thompson, Jeffrey S

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Practice Patterns and Outcomes of Transcatheter Aortic Valve Replacement in the United States and Japan: A Report From Joint Data Harmonization Initiative of STS/ACC TVT and J-TVT von Kaneko, Tsuyoshi, Vemulapalli, Sreekanth, Kohsaka, Shun, Shimamura, Kazuo, Stebbins, Amanda, Kumamaru, Hiraku, Nelson, Adam J, Kosinski, Andrzej, Maeda, Koichi, Bavaria, Joseph E, Saito, Shigeru, Reardon, Michael J, Kuratani, Toru, Popma, Jeffrey J, Inohara, Taku, Thourani, Vinod H, Carroll, John D, Shimizu, Hideyuki, Takayama, Morimasa, Leon, Martin B, Mack, Michael J, Sawa, Yoshiki

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Barriers to accrual and enrollment in brain tumor trials von Lee, Eudocia Q, Chukwueke, Ugonma N, Hervey-Jumper, Shawn L, de Groot, John F, Leone, Jose Pablo, Armstrong, Terri S, Chang, Susan M, Arons, David, Oliver, Kathy, Verble, Kay, Musella, Al, Willmarth, Nicole, Alexander, Brian M, Bates, Amanda, Doherty, Lisa, Galanis, Evanthia, Gaffey, Sarah, Halkin, Thomas, Friday, Bret E, Fouladi, Maryam, Lin, Nancy U, Macdonald, David, Mehta, Minesh P, Penas-Prado, Marta, Vogelbaum, Michael A, Sahebjam, Solmaz, Sandak, David, van den Bent, Martin, Weller, Michael, Reardon, David A, Wen, Patrick Y

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Mutations in PIK3R1 Cause SHORT Syndrome von Dyment, David A., Smith, Amanda C., Alcantara, Diana, Schwartzentruber, Jeremy A., Basel-Vanagaite, Lina, Curry, Cynthia J., Temple, I. Karen, Reardon, William, Mansour, Sahar, Haq, Mushfequr R., Gilbert, Rodney, Lehmann, Ordan J., Vanstone, Megan R., Beaulieu, Chandree L., Majewski, Jacek, Bulman, Dennis E., O’Driscoll, Mark, Boycott, Kym M., Innes, A. Micheil

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Unveiling errors in soil microbial community sequencing: a case for reference soils and improved diagnostics for nanopore sequencing von Manter, Daniel K., Reardon, Catherine L., Ashworth, Amanda J., Ibekwe, Abasiofiok M., Lehman, R. Michael, Maul, Jude E., Miller, Daniel N., Creed, Timothy, Ewing, Patrick M., Park, Stanley, Ducey, Thomas F., Tyler, Heather L., Veum, Kristen S., Weyers, Sharon L., Knaebel, David B.

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Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial von Parshuram, Christopher S, Dryden-Palmer, Karen, Farrell, Catherine, Gottesman, Ronald, Gray, Martin, Hutchison, James S, Helfaer, Mark, Hunt, Elizabeth A, Joffe, Ari R, Lacroix, Jacques, Moga, Michael Alice, Nadkarni, Vinay, Ninis, Nelly, Parkin, Patricia C, Wensley, David, Willan, Andrew R, Tomlinson, George A

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Characterization of early markers of disease in the mouse model of mucopolysaccharidosis IIIB von McCullough, Katherine B, Titus, Amanda, Reardon, Kate, Conyers, Sara, Dougherty, Joseph D, Ge, Xia, Garbow, Joel R, Dickson, Patricia, Yuede, Carla M, Maloney, Susan E

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Loss-of-Control Mitigation via Predictive Cuing von Stepanyan, Vahram, Krishnakumar, Kalmanje, Dorais, Greg, Reardon, Scott, Barlow, Jonathan, Lampton, Amanda, Hardy, Gordon

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CTIM-28. NEOADJUVANT ANTI-PD1 IMMUNOTHERAPY FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES OF A STAGE 2 SINGLE-ARM EXPANSION COHORT von Ricardo McFaline-Figueroa, J, Sun, Lu, Youssef, Gilbert, Huang, Raymond, Li, Gang, Kim, Jiyoon, Lee, Eudocia, Nayak, Lakshmi, Chukwueke, Ugonma, Beroukhim, Rameen, Batchelor, Tracy, Chiocca, E Antonio, Everson, Richard, Doherty, Lisa, Stefanik, Jennifer, Partridge, Kathryn, Spearman, Amanda, Myers, Alexa, Westergaard, Catharina, Russ, Alyssa, Lavallee, Maria, Smokovich, Anna, LaForest-Roys, Corey, Fox, Rachel Garcia, McCluskey, Christine, Bi, Wenya Linda, Arnaout, Omar, Peruzzi, PierPaolo, Cosgrove, G Rees, Ligon, Keith, Romany, Isabel Arrillaga, Clarke, Jennifer, Reardon, David, Cloughesy, Timothy, Prins, Robert, Wen, Patrick

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CTIM-25. NEOADJUVANT ANTI-PD1 IMMUNOTHERAPY FOR SURGICALLY ACCESSIBLE RECURRENT GLIOBLASTOMA: CLINICAL AND MOLECULAR OUTCOMES OF A STAGE 2 SINGLE-ARM EXPANSION COHORT von Ricardo McFaline-Figueroa, J, Prins, Robert, Qiao, Yu, Sun, Lu, Li, Gang, Kim, Jiyoon, Lee, Eudocia, Nayak, Lakshmi, Chukwueke, Ugonma, Beroukhim, Rameen, Batchelor, Tracy, Chiocca, E Antonio, Doherty, Lisa, Stefanik, Jennifer, Partridge, Kathryn, Spearman, Amanda, Lavallee, Maria, Myers, Alexa, Laforest-Roys, Corey, Garcia, Rachel Fox, Bi, Wenya Linda, Arnaout, Omar, Peruzzi, Pierpaolo, Cosgrove, G Rees, Ligon, Keith, Arrillaga-Romany, Isabel, Clarke, Jennifer, Reardon, David A, Cloughesy, Timothy, Wen, Patrick Y

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Genomic analysis of early-stage lung cancer reveals a role for TP53 mutations in distant metastasis von Van Egeren, Debra, Kohli, Khushi, Warner, Jeremy L., Bedard, Philippe L., Riely, Gregory, Lepisto, Eva, Schrag, Deborah, LeNoue-Newton, Michele, Catalano, Paul, Kehl, Kenneth L., Michor, Franziska

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How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum von BANKA, Siddharth, VEERAMACHANENI, Ratna, METCALFE, Kay, CHANDLER, Kate, MAGEE, Alex, STEWART, Fiona, MCCONNELL, Vivienne Pm, DONNELLY, Deirdre E, BERLAND, Siren, HOUGE, Gunnar, MORTON, Jenny E, OLEY, Christine, REARDON, William, REVENCU, Nicole, PARK, Soo-Mi, DAVIES, Sally J, FRY, Andrew E, ANN LYNCH, Sally, GILL, Harinder, SCHWEIGER, Susann, LAM, Wayne Wk, TOLMIE, John, MOHAMMED, Shehla N, HOWARD, Emma, HOBSON, Emma, SMITH, Audrey, BLYTH, Moira, BENNETT, Christopher, VASUDEVAN, Pradeep C, GARCIA-MINAUR, Sixto, HENDERSON, Alex, GOODSHIP, Judith, WRIGHT, Michael J, FISHER, Richard, BUNSTONE, Sancha, GIBBONS, Richard, PRICE, Susan M, DE SILVA, Deepthi C, KAREN TEMPLE, I, COLLINS, Amanda L, LACHLAN, Katherine, ELMSLIE, Frances, MCENTAGART, Meriel, CASTLE, Bruce, CLAYTON-SMITH, Jill, RAGGE, Nicola, BLACK, Graeme C, DONNAI, Dian, PARKER, Michael J, CROW, Yanick J, KERR, Bronwyn, KINGSTON, Helen

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Opioid analgesia in mechanically ventilated children: results from the multicenter Measuring Opioid Tolerance Induced by Fentanyl study von Anand, Kanwaljeet J S, Clark, Amy E, Willson, Douglas F, Berger, John, Meert, Kathleen L, Zimmerman, Jerry J, Harrison, Rick, Carcillo, Joseph A, Newth, Christopher J L, Bisping, Stephanie, Holubkov, Richard, Dean, J Michael, Nicholson, Carol E

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INNV-33. BARRIERS TO ACCRUAL AND ENROLLMENT IN BRAIN TUMOR TRIALS von Lee, Eudocia, Chukwueke, Ugonma, Hervey-Jumper, Shawn, DeGroot, John, Leone, Pablo, Armstrong, Terri, Chang, Susan, Arons, David, Oliver, Kathy, Verble, Kay, Musella, Al, Willmarth, Nicole, Alexander, Brian, Bates, Amanda, Doherty, Lisa, Galanis, Evanthia, Gaffey, Sarah, Halkin, Thomas, Friday, Bret, Fouladi, Maryam, Lin, Nancy, Macdonald, David, Mehta, Minesh, Penas-Prado, Marta, Vogelbaum, Michael, Sahebjam, Solmaz, Sandak, David, van den Bent, Martin, Weller, Michael, Reardon, David, Wen, Patrick

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