Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies von Yeung, Kap-Sun, Beno, Brett R, Parcella, Kyle, Bender, John A, Grant-Young, Katherine A, Nickel, Andrew, Gunaga, Prashantha, Anjanappa, Prakash, Bora, Rajesh Onkardas, Selvakumar, Kumaravel, Rigat, Karen, Wang, Ying-Kai, Liu, Mengping, Lemm, Julie, Mosure, Kathy, Sheriff, Steven, Wan, Changhong, Witmer, Mark, Kish, Kevin, Hanumegowda, Umesh, Zhuo, Xiaoliang, Shu, Yue-Zhong, Parker, Dawn, Haskell, Roy, Ng, Alicia, Gao, Qi, Colston, Elizabeth, Raybon, Joseph, Grasela, Dennis M, Santone, Kenneth, Gao, Min, Meanwell, Nicholas A, Sinz, Michael, Soars, Matthew G, Knipe, Jay O, Roberts, Susan B, Kadow, John F

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Pharmacodynamics of selective inhibition of γ-secretase by avagacestat von Albright, Charles F, Dockens, Randy C, Meredith, Jr, Jere E, Olson, Richard E, Slemmon, Randy, Lentz, Kimberley A, Wang, Jun-Sheng, Denton, R Rex, Pilcher, Gary, Rhyne, Paul W, Raybon, Joseph J, Barten, Donna M, Burton, Catherine, Toyn, Jeremy H, Sankaranarayanan, Sethu, Polson, Craig, Guss, Valerie, White, Randy, Simutis, Frank, Sanderson, Thomas, Gillman, Kevin W, Starrett, Jr, John E, Bronson, Joanne, Sverdlov, Oleksandr, Huang, Shu-Pang, Castaneda, Lorna, Feldman, Howard, Coric, Vlad, Zaczek, Robert, Macor, John E, Houston, John, Berman, Robert M, Tong, Gary

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Preclinical Pharmacokinetic/Pharmacodynamic Modeling and Simulation in the Pharmaceutical Industry: An IQ Consortium Survey Examining the Current Landscape von Schuck, Edgar, Bohnert, Tonika, Chakravarty, Arijit, Damian-Iordache, Valeriu, Gibson, Christopher, Hsu, Cheng-Pang, Heimbach, Tycho, Krishnatry, Anu Shilpa, Liederer, Bianca M, Lin, Jing, Maurer, Tristan, Mettetal, Jerome T, Mudra, Daniel R, Nijsen, Marjoleen JMA, Raybon, Joseph, Schroeder, Patricia, Schuck, Virna, Suryawanshi, Satyendra, Su, Yaming, Trapa, Patrick, Tsai, Alice, Vakilynejad, Majid, Wang, Shining, Wong, Harvey

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Pharmacokinetic-pharmacodynamic modeling of rifampicin-mediated Cyp3a11 induction in steroid and xenobiotic X receptor humanized mice von Raybon, Joseph J, Pray, Devin, Morgan, Daniel G, Zoeckler, Mary, Zheng, Ming, Sinz, Michael, Kim, Sean

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In response to "a gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system" von Raybon, Joseph J., Albright, Charles F.

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Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780 von Toyn, Jeremy H., Thompson, Lorin A., Lentz, Kimberley A., Meredith, Jere E., Burton, Catherine R., Sankaranararyanan, Sethu, Guss, Valerie, Hall, Tracey, Iben, Lawrence G., Krause, Carol M., Krause, Rudy, Lin, Xu-Alan, Pierdomenico, Maria, Polson, Craig, Robertson, Alan S., Denton, R. Rex, Grace, James E., Morrison, John, Raybon, Joseph, Zhuo, Xiaoliang, Snow, Kimberly, Padmanabha, Ramesh, Agler, Michele, Esposito, Kim, Harden, David, Prack, Margaret, Varma, Sam, Wong, Victoria, Zhu, Yingjie, Zvyaga, Tatyana, Gerritz, Samuel, Marcin, Lawrence R., Higgins, Mendi A., Shi, Jianliang, Wei, Cong, Cantone, Joseph L., Drexler, Dieter M., Macor, John E., Olson, Richard E., Ahlijanian, Michael K., Albright, Charles F.

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Alterations in neuronal transport but not blood-brain barrier transport are observed during gamma-hydroxybutyrate (GHB) sedative/hypnotic tolerance von BHATTACHARYA, Indranil, RAYBON, Joseph J, BOJE, Kathleen M. K

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Liquid chromatographic–mass spectrometric determination of endogenous γ-hydroxybutyrate concentrations in rat brain regions and plasma von Fung, Ho-Leung, Haas, Eric, Raybon, Joseph, Xu, Jian, Fung, Sun-Mi

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Discovery of Isonicotinamides as Highly Selective, Brain Penetrable, and Orally Active Glycogen Synthase Kinase‑3 Inhibitors von Luo, Guanglin, Chen, Ling, Burton, Catherine R, Xiao, Hong, Sivaprakasam, Prasanna, Krause, Carol M, Cao, Yang, Liu, Nengyin, Lippy, Jonathan, Clarke, Wendy J, Snow, Kimberly, Raybon, Joseph, Arora, Vinod, Pokross, Matt, Kish, Kevin, Lewis, Hal A, Langley, David R, Macor, John E, Dubowchik, Gene M

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Microtubule stabilizing agents as tools to explore the mechanism of Tau neurotoxicity in Alzheimer's disease and other Tauopathies von Barten, Donna M, Meredith, Jere E, Andorfer, Cathy, Polson, Craig, Hoque, Nina, Fiedler, Tracey, DeCarr, Lynn B, Goldstein, Margi, Raybon, Joseph J, Donegan, Michael, Corradi, John, Yang, Ling, Janus, Chris, Hutton, Mike, Lewis, Jada, Albright, Charles F

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The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers von Soares, Holly D, Gasior, Maciej, Toyn, Jeremy H, Wang, Jun-Sheng, Hong, Quan, Berisha, Flora, Furlong, Michael T, Raybon, Joseph, Lentz, Kimberley A, Sweeney, Francis, Zheng, Naiyu, Akinsanya, Billy, Berman, Robert M, Thompson, Lorin A, Olson, Richard E, Morrison, John, Drexler, Dieter M, Macor, John E, Albright, Charlie F, Ahlijanian, Michael K, AbuTarif, Malaz

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Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects von Toyn, Jeremy H, Boy, Kenneth M, Raybon, Joseph, Meredith, Jr, Jere E, Robertson, Alan S, Guss, Valerie, Hoque, Nina, Sweeney, Francis, Zhuo, Xiaoliang, Clarke, Wendy, Snow, Kimberly, Denton, R Rex, Zuev, Dmitry, Thompson, Lorin A, Morrison, John, Grace, James, Berisha, Flora, Furlong, Michael, Wang, Jun-Sheng, Lentz, Kimberly A, Padmanabha, Ramesh, Cook, Lynda, Wei, Cong, Drexler, Dieter M, Macor, John E, Albright, Charlie F, Gasior, Maciej, Olson, Richard E, Hong, Quan, Soares, Holly D, AbuTarif, Malaz, Ahlijanian, Michael K

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A critical evaluation of the brain efflux index method as applied to the nitric oxide synthase inhibitor, aminoguanidine von Raybon, Joseph J., Boje, Kathleen M.K.

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Discovery of Indazoles as Potent, Orally Active Dual Neurokinin 1 Receptor Antagonists and Serotonin Transporter Inhibitors for the Treatment of Depression von Degnan, Andrew P, Tora, George O, Huang, Hong, Conlon, David A, Davis, Carl D, Hanumegowda, Umesh M, Hou, Xiaoping, Hsiao, Yi, Hu, Joanna, Krause, Rudolph, Li, Yu-Wen, Newton, Amy E, Pieschl, Rick L, Raybon, Joseph, Rosner, Thorsten, Sun, Jung-Hui, Taber, Matthew T, Taylor, Sarah J, Wong, Michael K, Zhang, Huiping, Lodge, Nicholas J, Bronson, Joanne J, Macor, John E, Gillman, Kevin W

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P3‐187: Microtubule stabilizing agents as tools to explore the mechanism of Tau neurotoxicity in Alzheimer's disease and other Tauopathies von Barten, Donna M., Meredith, Jere E., Andorfer, Cathy, Polson, Craig, Hoque, Nina, Fiedler, Tracey, DeCarr, Lynn B., Goldstein, Margi, Raybon, Joseph J., Donegan, Michael, Corradi, John, Yang, Ling, Janus, Chris, Hutton, Mike, Lewis, Jada, Albright, Charles F.

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Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780 von Krause, Carol M., Krause, Rudy, Lin, Xu-Alan, Pierdomenico, Maria, Polson, Craig, Robertson, Alan S., Denton, R. Rex, Iben, Lawrence G., Hall, Tracey, Guss, Valerie, Sankaranararyanan, Sethu, Burton, Catherine R., Meredith, Jere E., Lentz, Kimberley A., Thompson, Lorin A., Toyn, Jeremy H., Grace, James E., Morrison, John, Raybon, Joseph, Zhuo, Xiaoliang, Snow, Kimberly, Padmanabha, Ramesh, Agler, Michele, Esposito, Kim, Harden, David, Prack, Margaret, Varma, Sam, Wong, Victoria, Zhu, Yingjie, Zvyaga, Tatyana, Gerritz, Samuel, Marcin, Lawrence R., Higgins, Mendi A., Shi, Jianliang, Wei, Cong, Cantone, Joseph L., Drexler, Dieter M., Macor, John E., Olson, Richard E., Ahlijanian, Michael K., Albright, Charles F.

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40-Gb/s tandem electroabsorption modulator von Mason, B., Ougazzaden, A., Lentz, C.W., Glogovsky, K.G., Reynolds, C.L., Przybylek, G.J., Leibenguth, R.E., Kercher, T.L., Boardman, J.W., Rader, M.T., Geary, J.M., Walters, F.S., Peticolas, L.J., Freund, J.M., Chu, S.N.G., Sirenko, A., Jurchenko, R.J., Hybertsen, M.S., Ketelsen, L.J.P., Raybon, G.

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InP DHBT circuits: From device physics to 40 Gb/s and 100 Gb/s transmission system experiments von Weimann, Nils, Houtsma, Vincent, Kopf, Rose, Baeyens, Yves, Weiner, Joseph, Tate, Alaric, Frackoviak, John, Chen, Young-Kai, Raybon, Gregory, Godin, Jean, Riet, Muriel, Nodjiadjim, Virginie, Konczykowska, Agnieszka, Dupuy, Jean-Yves, Jorge, Filipe, Scavennec, Andre, Charlet, Gabriel

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InP DHBT circuits: From device physics to 40Gb/s and 100Gb/s transmission system experiments von Weimann, Nils, Houtsma, Vincent, Kopf, Rose, Baeyens, Yves, Weiner, Joseph, Tate, Alaric, Frackoviak, John, Chen, Young-Kai, Raybon, Gregory, Godin, Jean, Riet, Muriel, Nodjiadjim, Virginie, Konczykowska, Agnieszka, Dupuy, Jean-Yves, Jorge, Filipe, Scavennec, André, Charlet, Gabriel

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Distributed Bragg reflector active optical filters von Tessler, N., Nagar, R., Eisenstein, G., Salzman, J., Koren, U., Raybon, G., Burns, C.A.

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