Abstract 3778: MBNL1 regulated alternative splicing of MAP2K7 promotes de-differentiation of cancer cells by activating JNK von Ray, Debleena

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RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia von Koschut, David, Ray, Debleena, Li, Zhenhua, Giarin, Emanuela, Groet, Jürgen, Alić, Ivan, Kham, Shirley Kow-Yin, Chng, Wee Joo, Ariffin, Hany, Weinstock, David M., Yeoh, Allen Eng-Juh, Basso, Giuseppe, Nižetić, Dean

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Acetylation of C/EBPα inhibits its granulopoietic function von Bararia, Deepak, Kwok, Hui Si, Welner, Robert S., Numata, Akihiko, Sárosi, Menyhárt B., Yang, Henry, Wee, Sheena, Tschuri, Sebastian, Ray, Debleena, Weigert, Oliver, Levantini, Elena, Ebralidze, Alexander K., Gunaratne, Jayantha, Tenen, Daniel G.

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Tumorigenic de-differentiation: the alternative splicing way von Ray, Debleena, Epstein, David M.

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Abstract LB-332: Aberrant splicing network delineated from next-gen RNA sequencing analyses identifies activated oncogenes and pathways in gastric cancer von Ray, Debleena

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Dichotomous transactivation domains contribute to growth inhibitory and promotion functions of TAp73 von Li, Dan, Kok, Catherine Yen Li, Wang, Chao, Ray, Debleena, Osterburg, Susanne, Dötsch, Volker, Ghosh, Sujoy, Sabapathy, Kanaga

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A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation von Ray, Debleena, Yun, Yu Chye, Idris, Muhammad, Cheng, Shanshan, Boot, Arnoud, Iain, Tan Bee Huat, Rozen, Steven G., Tan, Patrick, Epstein, David M.

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Gα-13 induces CXC motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB von Lim, Wei Kiang, Chai, Xiaoran, Ghosh, Sujoy, Ray, Debleena, Wang, Mei, Rasheed, Suhail Ahmed Kabeer, Casey, Patrick J.

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Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression von Ray, Debleena, Kwon, So Yeon, Tagoh, Hiromi, Heidenreich, Olaf, Ptasinska, Anetta, Bonifer, Constanze

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532 Anti-VISTA antibody HMBD-002 reprograms tumour associated macrophages and promotes cytotoxic T cell response von Dharmadhikari, Bhushan, Thakkar, Dipti, Zharkova, Olga, Ray, Debleena, Lai, Jason, Paszkiewicz, Konrad, Ingram, Piers, Boyd-Kirkup, Jerome

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Chronic growth factor receptor signaling and lineage inappropriate gene expression in AML: The polycomb connection von Ray, Debleena, Kwon, So Yeon, Ptasinska, Anetta, Bonifer, Constanze

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Abstract 2659: Anti-HER3 antibody, HMBD-001, in combination with an EGFR inhibitor effectively inhibits tumor growth in biomarker-selected pre-clinical models of squamous cell carc... von Toy, Weiyi, Thakkar, Dipti, Luu, Khang, Chi, Bui Ngoc Linh, Lai, Jason, Ray, Debleena, Gandhi, Namita, Mas, Alejandro, Paszkiewicz, Konrad, Ingram, Piers, Boyd-Kirkup, Jerome

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Gα-13 induces C X C motif chemokine ligand 5 expression in prostate cancer cells by transactivating NF-κB von Lim, Wei Kiang, Chai, Xiaoran, Ghosh, Sujoy, Ray, Debleena, Wang, Mei, Rasheed, Suhail Ahmed Kabeer, Casey, Patrick J

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Acetylation of C/EBPα inhibits its granulopoietic function von Bararia, Deepak, Kwok, Hui Si, Welner, Robert S, Numata, Akihiko, Sárosi, Menyhárt B, Yang, Henry, Wee, Sheena, Tschuri, Sebastian, Ray, Debleena, Weigert, Oliver, Levantini, Elena, Ebralidze, Alexander K, Gunaratne, Jayantha, Tenen, Daniel G

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The molecular mechanism of the aberrant expression of the B-cell specific PAX5 gene in t(8;21) AML von Ray, Debleena

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A functional network of gastric-cancer-associated splicing events controlled by dysregulated splicing factors von Cheng, Shanshan, Ray, Debleena, Lee, Raymond Teck Ho, Naripogu, Kishore Babu, Yusoff, Permeen Akhtar Bt Mohamed, Goh, Pamela Bee Leng, Liu, Yujing, Suzuki, Yuka, Das, Kakoli, Chan, Hsiang Sui, Wong, Wai Keong, Chan, Weng Hoong, Chow, Pierce Kah-Hoe, Ong, Hock Soo, Raj, Prema, Soo, Khee Chee, Tan, Patrick, Epstein, David M, Rozen, Steven G

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Acetylation of C/EBP[alpha] inhibits its granulopoietic function von Bararia, Deepak, Kwok, Hui Si, Welner, Robert S, Numata, Akihiko, Sárosi, Menyhárt B, Yang, Henry, Wee, Sheena, Tschuri, Sebastian, Ray, Debleena, Weigert, Oliver, Levantini, Elena, Ebralidze, Alexander K, Gunaratne, Jayantha, Tenen, Daniel G

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TREATMENT AND PREVENTION OF CANCER USING VISTA ANTIGEN-BINDING MOLECULES von DHARMADHIKARI, Bhushan, INGRAM, Piers, ZHARKOVA, Olga, RAY, Debleena, PASZKIEWICZ, Konrad, TIRADO-MAGALLANES, Roberto, THAKKAR, Dipti, BOYD-KIRKUP, Jerome

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Acetylation of C/EBP alpha inhibits its granulopoietic function von Bararia, Deepak, Kwok, Hui Si, Welner, Robert S, Numata, Akihiko, Sárosi, Menyhárt B, Yang, Henry, Wee, Sheena, Tschuri, Sebastian, Ray, Debleena, Weigert, Oliver, Levantini, Elena, Ebralidze, Alexander K, Gunaratne, Jayantha, Tenen, Daniel G

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